Antiepileptic Drug Nonadherence and Its Predictors among People with Epilepsy
Introduction. Antiepileptic drugs are effective in the treatment of epilepsy to the extent that about 70% of people with epilepsy can be seizure-free, but poor adherence to medication is major problem to sustained remission and functional restoration. The aim of this study was to assess the prevalen...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Behavioural Neurology |
| Online Access: | http://dx.doi.org/10.1155/2016/3189108 |
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| author | Asmamaw Getnet Solomon Meseret Woldeyohannes Lulu Bekana Tesfa Mekonen Wubalem Fekadu Melak Menberu Solomon Yimer Adisu Assaye Amsalu Belete Habte Belete |
| author_facet | Asmamaw Getnet Solomon Meseret Woldeyohannes Lulu Bekana Tesfa Mekonen Wubalem Fekadu Melak Menberu Solomon Yimer Adisu Assaye Amsalu Belete Habte Belete |
| author_sort | Asmamaw Getnet |
| collection | DOAJ |
| description | Introduction. Antiepileptic drugs are effective in the treatment of epilepsy to the extent that about 70% of people with epilepsy can be seizure-free, but poor adherence to medication is major problem to sustained remission and functional restoration. The aim of this study was to assess the prevalence and associated factors of antiepileptic drug nonadherence. Methods. Cross-sectional study was conducted on 450 individuals who were selected by systematic random sampling method. Antiepileptic drug nonadherence was measured by Morisky Medication Adherence Scale (MMAS) and logistic regression was used to look for significant associations. Result. The prevalence of AEDs nonadherence was 37.8%. Being on treatment for 6 years and above [AOR = 3.47, 95% CI: 1.88, 6.40], payment for AEDs [AOR = 2.76, 95% CI: 1.73, 4.42], lack of health information [AOR = 2.20, 95% CI: 1.41,3.43], poor social support [AOR = 1.88, 95%, CI: 1.01, 3.50], perceived stigma [AOR = 2.27, 95% CI: 1.45, 3.56], and experience side effect [AOR = 1.70, 95% CI: 1.06, 2.72] were significantly associated with antiepileptic drug nonadherence. Conclusion. More than one-third of people with epilepsy were not compliant with their AEDs. Giving health information about epilepsy and its management and consequent reduction in stigma will help for medication adherence. |
| format | Article |
| id | doaj-art-475c3bbe77e04d638d8659392b5fcd32 |
| institution | Kabale University |
| issn | 0953-4180 1875-8584 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Behavioural Neurology |
| spelling | doaj-art-475c3bbe77e04d638d8659392b5fcd322025-08-20T03:36:46ZengWileyBehavioural Neurology0953-41801875-85842016-01-01201610.1155/2016/31891083189108Antiepileptic Drug Nonadherence and Its Predictors among People with EpilepsyAsmamaw Getnet0Solomon Meseret Woldeyohannes1Lulu Bekana2Tesfa Mekonen3Wubalem Fekadu4Melak Menberu5Solomon Yimer6Adisu Assaye7Amsalu Belete8Habte Belete9Finote Selam Hospital, Finote Selam, EthiopiaDiseases Prevention and Control, School of Public Health, University of Queensland, Brisbane, QLD, AustraliaAmanuel Mental Specialized Hospital, Addis Ababa, EthiopiaCollege of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, EthiopiaCollege of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, EthiopiaCollege of Health Sciences, Mizan Tepi University, Mizan, EthiopiaPsychiatry Department, College of Health Sciences and Medicine, Dilla University, Dilla, EthiopiaDebre Markos University, Debre Markos, EthiopiaCollege of Medicine and Health Sciences, Debre Tabor University, Debre Tabor, EthiopiaCollege of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, EthiopiaIntroduction. Antiepileptic drugs are effective in the treatment of epilepsy to the extent that about 70% of people with epilepsy can be seizure-free, but poor adherence to medication is major problem to sustained remission and functional restoration. The aim of this study was to assess the prevalence and associated factors of antiepileptic drug nonadherence. Methods. Cross-sectional study was conducted on 450 individuals who were selected by systematic random sampling method. Antiepileptic drug nonadherence was measured by Morisky Medication Adherence Scale (MMAS) and logistic regression was used to look for significant associations. Result. The prevalence of AEDs nonadherence was 37.8%. Being on treatment for 6 years and above [AOR = 3.47, 95% CI: 1.88, 6.40], payment for AEDs [AOR = 2.76, 95% CI: 1.73, 4.42], lack of health information [AOR = 2.20, 95% CI: 1.41,3.43], poor social support [AOR = 1.88, 95%, CI: 1.01, 3.50], perceived stigma [AOR = 2.27, 95% CI: 1.45, 3.56], and experience side effect [AOR = 1.70, 95% CI: 1.06, 2.72] were significantly associated with antiepileptic drug nonadherence. Conclusion. More than one-third of people with epilepsy were not compliant with their AEDs. Giving health information about epilepsy and its management and consequent reduction in stigma will help for medication adherence.http://dx.doi.org/10.1155/2016/3189108 |
| spellingShingle | Asmamaw Getnet Solomon Meseret Woldeyohannes Lulu Bekana Tesfa Mekonen Wubalem Fekadu Melak Menberu Solomon Yimer Adisu Assaye Amsalu Belete Habte Belete Antiepileptic Drug Nonadherence and Its Predictors among People with Epilepsy Behavioural Neurology |
| title | Antiepileptic Drug Nonadherence and Its Predictors among People with Epilepsy |
| title_full | Antiepileptic Drug Nonadherence and Its Predictors among People with Epilepsy |
| title_fullStr | Antiepileptic Drug Nonadherence and Its Predictors among People with Epilepsy |
| title_full_unstemmed | Antiepileptic Drug Nonadherence and Its Predictors among People with Epilepsy |
| title_short | Antiepileptic Drug Nonadherence and Its Predictors among People with Epilepsy |
| title_sort | antiepileptic drug nonadherence and its predictors among people with epilepsy |
| url | http://dx.doi.org/10.1155/2016/3189108 |
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