Distinct white matter alteration patterns in post-infectious and gradual onset chronic fatigue syndrome revealed by diffusion MRI

Distinct white matter alteration patterns in post-infectious and gradual onset chronic fatigue syndrome revealed by diffusion MRI

Abstract While post-infectious (PI-ME/CFS) and gradual onset (GO-ME/CFS) myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) manifest similar symptoms, it has long been suspected that different disease processes underlie them. However, the lack of biological evidence has left this question u...

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Bibliographic Details
Main Authors: Qiang Yu, Richard A. Kwiatek, Peter Del Fante, Anya Bonner, Vince D. Calhoun, Grant A. Bateman, Takashi Yamamura, Zack Y. Shan
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Myalgic encephalomyelitis/Chronic fatigue syndrome
Post-infectious
Gradual onset
Diffusion tensor imaging
Axial diffusivity
White matter microstructure
Online Access:https://doi.org/10.1038/s41598-025-09379-z
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