Antidiabetic Activity of Benzopyrone Analogues in Nicotinamide-Streptozotocin Induced Type 2 Diabetes in Rats

Antidiabetic Activity of Benzopyrone Analogues in Nicotinamide-Streptozotocin Induced Type 2 Diabetes in Rats

Benzopyrones are proven antidiabetic drug candidate in diabetic drug discovery. In this view novel synthetic benzopyrone analogues were selected for testing in experimental diabetes. Type 2 diabetes (T2D) was induced in Wistar rats by streptozotocin (60 mg/kg, i.p.) followed by nicotinamide (120 mg/...

Full description

Saved in:

Bibliographic Details
Main Authors:	Yogendra Nayak, Venkatachalam Hillemane, Vijay Kumar Daroji, B. S. Jayashree, M. K. Unnikrishnan
Format:	Article
Language:	English
Published:	Wiley 2014-01-01
Series:	The Scientific World Journal
Online Access:	http://dx.doi.org/10.1155/2014/854267
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Antidiabetic and Antioxidant Properties of Triticum aestivum in Streptozotocin-Induced Diabetic Rats
by: Yogesha Mohan, et al.
Published: (2013-01-01)

Pharmacological Studies on the Antidiabetic, Antioxidant, and Antimicrobial Efficacies of Commiphora myrrha Resin in Streptozotocin-Induced Diabetes in Rats: A Preclinical Study
by: Rasha A. Mansouri, et al.
Published: (2023-01-01)

Characterisation of Pain Responses in the High Fat Diet/Streptozotocin Model of Diabetes and the Analgesic Effects of Antidiabetic Treatments
by: Frederika Maria Byrne, et al.
Published: (2015-01-01)

Morphological Changes of Gingiva in Streptozotocin Diabetic Rats
by: C. Tesseromatis, et al.
Published: (2009-01-01)

Cardiopulmonary Profile in Streptozotocin-Induced Type 1 Diabetic Rats during Systemic Endotoxemia
by: Ching-Hsia Hung, et al.
Published: (2013-01-01)

Combined Administration of Streptozotocin and Sucrose Accelerates the Appearance of Type 2 Diabetes Symptoms in Rats
by: Martha Isela Barragán-Bonilla, et al.
Published: (2019-01-01)

Antihyperglycemic Activity of Houttuynia cordata Thunb. in Streptozotocin-Induced Diabetic Rats
by: Manish Kumar, et al.
Published: (2014-01-01)

Evaluation of Antidiabetic Properties of the Leaves Extract of Ficus vallis-choudae Delile in a Model of Type 2 Diabetes Induced by High-Fat Diet and Streptozotocin
by: Kilenma Kolefer, et al.
Published: (2021-01-01)

Spironolactone Protects against Diabetic Cardiomyopathy in Streptozotocin-Induced Diabetic Rats
by: Wenjuan Liu, et al.
Published: (2018-01-01)

An in-vivo herb-drug interaction study of IME-9 and glimepiride in nicotinamide-STZ-induced diabetic rats
by: Archana K. Thikekar, et al.
Published: (2025-05-01)

Anti-hyperglycemic effects of dihydromyricetin in streptozotocin-induced diabetic rats
by: Maojun Yao, et al.
Published: (2021-03-01)

Intermittent Fasting Modulation of the Diabetic Syndrome in Streptozotocin-Injected Rats
by: Louiza Belkacemi, et al.
Published: (2012-01-01)

Beneficial Effect of Cissus quadrangularis Linn. on Osteopenia Associated with Streptozotocin-Induced Type 1 Diabetes Mellitus in Male Wistar Rats
by: Srinivasa Rao Sirasanagandla, et al.
Published: (2014-01-01)

BF3·Et2O Catalysed 4-Aryl-3-phenyl-benzopyrones, Pro-SERMs, and Their Characterization
by: Ambika Srivastava, et al.
Published: (2015-01-01)

Hypoglychemic activity of Moringa oleifera extract in streptozotocin-induced diabetic rats
by: Rabiatul Adawiyah, et al.
Published: (2024-08-01)

Evaluation of antihyperlipidemic effect of rosemary oil in streptozotocin-induced diabetic rats
by: Deniz Uluisik, et al.
Published: (2024-03-01)

Hematological effects of coenzyme q10 in streptozotocin-induced diabetic rats
by: Ercan Keskin, et al.

Chrysoeriol ameliorates hyperglycemia by regulating the carbohydrate metabolic enzymes in streptozotocin-induced diabetic rats
by: Baskaran Krishnan, et al.
Published: (2020-12-01)

Inhibitory Effect of r-Hirudin Variant III on Streptozotocin-Induced Diabetic Cataracts in Rats
by: Xiaojian Gong, et al.
Published: (2013-01-01)

Gene Expression Profiling of the Sciatic Nerve in Streptozotocin-Induced Diabetic Rats with Peripheral Neuropathy
by: Yiji Tu, et al.
Published: (2020-01-01)

Exogenous Angiotensin I Metabolism in Aorta Isolated from Streptozotocin Treated Diabetic Rats
by: P. P. Wołkow, et al.
Published: (2016-01-01)

The Haematological Effects of Oleanolic Acid in Streptozotocin-Induced Diabetic Rats: Effects on Selected Markers
by: Charity M. Baloyi, et al.
Published: (2019-01-01)

The Effects of MicroRNAs on Cardiomyopathy in a Rat Model of Streptozotocin-induced Diabetes Mellitus
by: Aslıhan Şeyda DOĞAN, et al.
Published: (2025-01-01)

Dietary Choline Deprivation Exacerbates Kidney Injury in Streptozotocin-Induced Diabetes in Adult Rats
by: Ahmed W. Al-Humadi, et al.
Published: (2025-01-01)

Molecular Findings Before Vision Loss in the Streptozotocin-Induced Rat Model of Diabetic Retinopathy
by: Mădălina Moldovan, et al.
Published: (2025-01-01)

Determination of NAD+ precursors nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR) in plant foods: exploring dietary sources
by: Gabriela Fabiana Soares Alegre, et al.
Published: (2025-12-01)

Evaluation of the antidiabetic and antinephritic effects of Pueraria tuberosa and Pterocarpus santalinus extracts co-encapsulated in nanostructured lipid carriers in streptozotocin-induced mouse model
by: Gyamcho Tshering Bhutia, et al.
Published: (2025-02-01)

Danhong Huayu Koufuye Prevents Diabetic Retinopathy in Streptozotocin-Induced Diabetic Rats via Antioxidation and Anti-Inflammation
by: Wenpei Chen, et al.
Published: (2017-01-01)

Quercetin improves diabetic kidney disease by inhibiting ferroptosis and regulating the Nrf2 in streptozotocin-induced diabetic rats
by: Lei Zhang, et al.
Published: (2024-12-01)

The Impact of Antidiabetic Agents on Sarcopenia in Type 2 Diabetes: A Literature Review
by: Chen-Ning Wu, et al.
Published: (2020-01-01)

Febuxostat Attenuates Renal Damage besides Exerting Hypouricemic Effect in Streptozotocin-Induced Diabetic Rats
by: Jianmin Ran, et al.
Published: (2017-01-01)

Study on effects and relevant mechanisms of Mudan granules on renal fibrosis in streptozotocin-induced diabetes rats
by: Mushuang Qi, et al.
Published: (2024-12-01)

Partial Replacement with Menhaden Oil Improves Peripheral Neuropathy in High-Fat-Fed Low-Dose Streptozotocin Type 2 Diabetic Rat
by: Lawrence J. Coppey, et al.
Published: (2012-01-01)

Noninsulin Antidiabetic Drugs for Patients with Type 2 Diabetes Mellitus: Are We Respecting Their Contraindications?
by: Irene Ruiz-Tamayo, et al.
Published: (2016-01-01)

The effects of the urotensin-II receptor antagonist palosuran treatment on the corpora cavernosa of streptozotocin-induced diabetic rats
by: Murat Olukman, et al.
Published: (2025-01-01)

Pharmacoeconomics and Utilisation of Antidiabetic Medications among Type 2 Diabetes Mellitus Patients: A Longitudinal Study
by: Bikash Chandra Das, et al.
Published: (2025-01-01)

Pinitol Improves Diabetic Foot Ulcers in Streptozotocin-Induced Diabetes Rats Through Upregulation of Nrf2/HO-1 Signaling
by: Jinsick Kim, et al.
Published: (2024-12-01)

Safety and efficacy of long-term nicotinamide mononucleotide supplementation on metabolism, sleep, and nicotinamide adenine dinucleotide biosynthesis in healthy, middle-aged Japanese men
by: Shintaro Yamaguchi, et al.
Published: (2024-02-01)

Combined Inositol Hexakisphosphate and Inositol Supplement Consumption Improves Serum Alpha-Amylase Activity and Hematological Parameters in Streptozotocin-Induced Type 2 Diabetic Rats
by: Shadae R. Foster, et al.
Published: (2019-01-01)

Effect of Aloe vera gel on the parotid glands of streptozotocin-induced diabetic albino rats: histological and immunohistochemical study.
by: Shukria Mohammed Hussein
Published: (2022-07-01)