Training-induced plasma miR-29a-3p is secreted by skeletal muscle and contributes to metabolic adaptations to resistance exercise in mice

Training-induced plasma miR-29a-3p is secreted by skeletal muscle and contributes to metabolic adaptations to resistance exercise in mice

Objective: The adaptive response to different models of regular exercise involves complex tissue crosstalk. Our aim was to explore the involvement of extracellular vesicle (EV) microRNAs (miRNAs) in this process, the secretory role of skeletal muscle and its functional metabolic interaction with the...

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Main Authors: Paola Pinto-Hernandez, Manuel Fernandez-Sanjurjo, Daan Paget, Xurde M. Caravia, David Roiz-Valle, Juan Castilla-Silgado, Sergio Diez-Robles, Almudena Coto-Vilcapoma, David Fernandez-Vivero, Pau Gama-Perez, Pablo M. Garcia-Roves, Carlos Lopez-Otin, Juleen R. Zierath, Anna Krook, Benjamin Fernandez-Garcia, Cristina Tomas-Zapico, Eduardo Iglesias-Gutierrez
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Molecular Metabolism
Subjects:
microRNAs
Exercise training
miR-29 family
Extracellular vesicles
Energy metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877825000808
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