Early toxicity of high-dose methotrexate in the treatment of non-hodgkin lymphomas in children

Early toxicity of high-dose methotrexate in the treatment of non-hodgkin lymphomas in children

Background. Methotrexate (MTX), used in high doses (1000–5000 mg / m2), has proven to be one of the key components of successful therapy for non‑Hodgkin’s lymphomas. However, the flip side of high efficacy is its toxicity. Even adherence to modern guidelines for supportive care, including therapeuti...

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Bibliographic Details
Main Authors: Z. K. Simavonyan, T. T. Valiev, Yu. E. Ryabukhina, P. A. Zeynalova
Format: Article
Language:Russian
Published: ABV-press 2025-03-01
Series:Онкогематология
Subjects:
methotrexate
non‑hodgkin’s lymphomas
toxicity
Online Access:https://oncohematology.abvpress.ru/ongm/article/view/1002
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