Features of lipid metabolism and hemostasis in patients with arterial hypertension underwent a new coronavirus infection COVID-19
An increase in the frequency of patients with arterial hypertension (AH) seeking medical care and its more severe course after a novel coronavirus infection (NCI), COVID-19, determines the need to study possible pathogenetic mechanisms of disease progression. Aim of the study was to investigate some...
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| Language: | Russian |
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Russian Academy of Sciences, Siberian Branch Publishing House
2024-11-01
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| Series: | Сибирский научный медицинский журнал |
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| Online Access: | https://sibmed.elpub.ru/jour/article/view/1720 |
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| author | E. V. Sevostyanova Yu. A. Nikolaev V. Ya. Polyakov I. L. Emelyanova |
| author_facet | E. V. Sevostyanova Yu. A. Nikolaev V. Ya. Polyakov I. L. Emelyanova |
| author_sort | E. V. Sevostyanova |
| collection | DOAJ |
| description | An increase in the frequency of patients with arterial hypertension (AH) seeking medical care and its more severe course after a novel coronavirus infection (NCI), COVID-19, determines the need to study possible pathogenetic mechanisms of disease progression. Aim of the study was to investigate some features of lipid metabolism and changes in hemostasis in patients with AH after NCI COVID-19. Material and methods. An analysis of the most informative indicators of lipid metabolism and hemostasis was carried out in 104 patients with AH underwent (more than 2 months ago) NCI, in comparison with 117 patients with AH, with no history of COVID-19. The study included men and women aged from 30 to 75 years. Determination of the concentration of lipids in blood serum was carried out using the photometric method on a biochemical analyzer AU 480 (Beckman Coulter, США). Hemostatic parameters were determined by the chromogenic method using an automatic hemostasis analyzer Technology Solution 190 (USA). Results and discussion. It was found that patients with AH underwent NCI had significantly higher serum levels of total cholesterol, LDL cho- lesterol, triglycerides, D-dimers, platelets and lower activated partial thromboplastin and thrombin time compared with patients without COVID-19. Conclusions. The data obtained indicate a tendency to atherogenic changes in the blood lipid profile and increased coagulation processes in patients with AH in the long-term period (more than 2 months) after suffering a NCI COVID-19. |
| format | Article |
| id | doaj-art-4715ac7efd684900a5a81eee3abd67e6 |
| institution | Kabale University |
| issn | 2410-2512 2410-2520 |
| language | Russian |
| publishDate | 2024-11-01 |
| publisher | Russian Academy of Sciences, Siberian Branch Publishing House |
| record_format | Article |
| series | Сибирский научный медицинский журнал |
| spelling | doaj-art-4715ac7efd684900a5a81eee3abd67e62025-08-20T03:50:44ZrusRussian Academy of Sciences, Siberian Branch Publishing HouseСибирский научный медицинский журнал2410-25122410-25202024-11-0144518118610.18699/SSMJ20240521696Features of lipid metabolism and hemostasis in patients with arterial hypertension underwent a new coronavirus infection COVID-19E. V. Sevostyanova0Yu. A. Nikolaev1V. Ya. Polyakov2I. L. Emelyanova3Federal Research Center of Fundamental and Translational MedicineFederal Research Center of Fundamental and Translational MedicineFederal Research Center of Fundamental and Translational MedicineFederal Research Center of Fundamental and Translational MedicineAn increase in the frequency of patients with arterial hypertension (AH) seeking medical care and its more severe course after a novel coronavirus infection (NCI), COVID-19, determines the need to study possible pathogenetic mechanisms of disease progression. Aim of the study was to investigate some features of lipid metabolism and changes in hemostasis in patients with AH after NCI COVID-19. Material and methods. An analysis of the most informative indicators of lipid metabolism and hemostasis was carried out in 104 patients with AH underwent (more than 2 months ago) NCI, in comparison with 117 patients with AH, with no history of COVID-19. The study included men and women aged from 30 to 75 years. Determination of the concentration of lipids in blood serum was carried out using the photometric method on a biochemical analyzer AU 480 (Beckman Coulter, США). Hemostatic parameters were determined by the chromogenic method using an automatic hemostasis analyzer Technology Solution 190 (USA). Results and discussion. It was found that patients with AH underwent NCI had significantly higher serum levels of total cholesterol, LDL cho- lesterol, triglycerides, D-dimers, platelets and lower activated partial thromboplastin and thrombin time compared with patients without COVID-19. Conclusions. The data obtained indicate a tendency to atherogenic changes in the blood lipid profile and increased coagulation processes in patients with AH in the long-term period (more than 2 months) after suffering a NCI COVID-19.https://sibmed.elpub.ru/jour/article/view/1720covid-19lipid metabolismhemostasiscomorbidity |
| spellingShingle | E. V. Sevostyanova Yu. A. Nikolaev V. Ya. Polyakov I. L. Emelyanova Features of lipid metabolism and hemostasis in patients with arterial hypertension underwent a new coronavirus infection COVID-19 Сибирский научный медицинский журнал covid-19 lipid metabolism hemostasis comorbidity |
| title | Features of lipid metabolism and hemostasis in patients with arterial hypertension underwent a new coronavirus infection COVID-19 |
| title_full | Features of lipid metabolism and hemostasis in patients with arterial hypertension underwent a new coronavirus infection COVID-19 |
| title_fullStr | Features of lipid metabolism and hemostasis in patients with arterial hypertension underwent a new coronavirus infection COVID-19 |
| title_full_unstemmed | Features of lipid metabolism and hemostasis in patients with arterial hypertension underwent a new coronavirus infection COVID-19 |
| title_short | Features of lipid metabolism and hemostasis in patients with arterial hypertension underwent a new coronavirus infection COVID-19 |
| title_sort | features of lipid metabolism and hemostasis in patients with arterial hypertension underwent a new coronavirus infection covid 19 |
| topic | covid-19 lipid metabolism hemostasis comorbidity |
| url | https://sibmed.elpub.ru/jour/article/view/1720 |
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