Lymphatic uptake and pharmacokinetics of lipid conjugated brush PEG polymers is altered by interactions with albumin and lipoproteins

Lymphatic uptake and pharmacokinetics of lipid conjugated brush PEG polymers is altered by interactions with albumin and lipoproteins

IntroductionIncreased recognition of the role of lymphatics in disease has brought increased focus on the design of lymph-directed delivery systems for imaging agents and therapeutics. Previously, we developed novel brush polyethylene glycol (PEG) polymers functionalized with different lipids and in...

Full description

Saved in:
Bibliographic Details
Main Authors: Mohammad Abdallah, Ian K. Styles, Alexander Mörsdorf, James L. Grace, John F. Quinn, Michael R. Whittaker, Natalie L. Trevaskis
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Physiology
Subjects:
lymphatic transport
lymphatic delivery
lipid
polymer
albumin
lipoprotein
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2025.1610791/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items