Full-Length Sequence Analysis of Chloroquine Resistance Transporter Gene in Plasmodium falciparum Isolates from Sabah, Malaysia

Full-Length Sequence Analysis of Chloroquine Resistance Transporter Gene in Plasmodium falciparum Isolates from Sabah, Malaysia

Chloroquine resistance (CQR) in falciparum malaria was identified to be associated with several mutations in the chloroquine resistance transporter gene (pfcrt) that encodes the transmembrane transporter in digestive vacuole membrane of the parasite. This study aimed to investigate the point mutatio...

Full description

Saved in:

Bibliographic Details
Main Authors:	Lii Lian Tan, Tiek Ying Lau, William Timothy, Dhanaraj Prabakaran
Format:	Article
Language:	English
Published:	Wiley 2014-01-01
Series:	The Scientific World Journal
Online Access:	http://dx.doi.org/10.1155/2014/935846
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Exposure and infection to Plasmodium knowlesi in case study communities in Northern Sabah, Malaysia and Palawan, The Philippines.
by: Kimberly M Fornace, et al.
Published: (2018-06-01)

Household costs associated with zoonotic Plasmodium knowlesi, P. falciparum, P. vivax and P. malariae infections in Sabah, Malaysia.
by: Patrick Abraham, et al.
Published: (2025-04-01)

In vitro antiplasmodial activity of six plants against chloroquine-sensitive and resistant strains of Plasmodium falciparum
by: Samuel Korsah
Published: (2025-01-01)

Combining shells and sequences to untangle taxonomy of abalone in Sabah, Malaysia
by: Nur-Syahirah Mamat, et al.
Published: (2025-06-01)

Prevalence of Plasmodium falciparum parasites harbouring chloroquine-resistant but not artemisinin-resistant alleles in Busia County, Western Kenya
by: Noah Machuki Onchieku, et al.
Published: (2025-07-01)

Comparative Study of Antimalarial Effect of Sambiloto (Andrographis paniculata) Extract, Chloroquine and Artemisinin and Their Combination Against Plasmodium falciparum In-vitro
by: Umar Zein, et al.
Published: (2013-01-01)

Comparative Study of Antimalarial Effect of Sambiloto (Andrographis paniculata) Extract, Chloroquine and Artemisinin and Their Combination Against Plasmodium falciparum In-vitro
by: Umar Zein, et al.
Published: (2013-01-01)

Comparative Study of Antimalarial Effect of Sambiloto (Andrographis paniculata) Extract, Chloroquine and Artemisinin and Their Combination Against Plasmodium falciparum In-vitro
by: Umar Zein, et al.
Published: (2013-01-01)

Treatment of erythrocytes with the 2-cys peroxiredoxin inhibitor, Conoidin A, prevents the growth of Plasmodium falciparum and enhances parasite sensitivity to chloroquine.
by: Mariana Brizuela, et al.
Published: (2014-01-01)

Epidemiology and Clinical Characteristics of Urogenital Tuberculosis in Sabah, Malaysia
by: Karthikayenee Ramasamy, et al.
Published: (2022-03-01)

In Vitro Antimalarial Activity of Chloroquine-Crocus Sativus Conjugated to Chitosan Nanocomposits against 3D7 and K1 Strains of Plasmodium falciparum
by: Aram Khezri, et al.
Published: (2025-06-01)

Rapid and supersensitive allele detection of Plasmodium falciparum chloroquine resistance via a Pyrococcus furiosus argonaute-triggered dual-signal biosensing platform
by: Liying Chen, et al.
Published: (2024-11-01)

Infection length and host environment influence on Plasmodium falciparum dry season reservoir
by: Carolina M Andrade, et al.
Published: (2024-09-01)

The diversity of Orthoptera in the northwestern parts of Mount Kinabalu, Sabah, Malaysia
by: Amira Aqilah Muhammad, et al.
Published: (2025-02-01)

Prevalence of chikungunya virus infection in Sabah, Malaysia during 2017–2020
by: Mya Myat Ngwe Tun, et al.
Published: (2025-04-01)

THE ABU SAYYAF GROUP AND KIDNAPPING FOR RANSOM IN SABAH, MALAYSIA, 2000–2023
by: Ramli Dollah, et al.
Published: (2025-04-01)

Does mass chloroquine treatment have any role in the elimination of Plasmodium vivax ?
by: Nicholas J. White, et al.
Published: (2025-05-01)

Molecular basis of the functional conflict between chloroquine and peptide transport in the Malaria parasite chloroquine resistance transporter PfCRT
by: John D. Tanner, et al.
Published: (2025-03-01)

Heavy metal pollution assessment in marine sediments in the Northwest coast of Sabah, Malaysia
by: Sin-Yi Ling, et al.
Published: (2023-10-01)

Factors associated with incomplete latent tuberculosis infection preventive treatment in Sabah, Malaysia
by: Ahmad Firdaus Mohamed, et al.
Published: (2025-07-01)

Mating Sumatran rhinoceros at Sepilok Rhino Breeding Centre, Sandakan, Sabah, Malaysia
by: E.J. Bosi
Published: (1996-06-01)

Manajemen Pendidikan Karakter di Sekolah Indonesia Kota Kinabalu, Sabah-Malaysia
by: Edi Purwanto, et al.
Published: (2024-12-01)

Inhibitors of Protein Targets of Plasmodium falciparum
by: Solomon Uche Oranusi, et al.
Published: (2024-12-01)

Sensitive and modular amplicon sequencing of Plasmodium falciparum diversity and resistance for research and public health
by: Andrés Aranda-Díaz, et al.
Published: (2025-03-01)

Characterization of within-host Plasmodium falciparum diversity using next-generation sequence data.
by: Sarah Auburn, et al.
Published: (2012-01-01)

Risk factor for gametocyte carriage and gametocytemia in Plasmodium vivax and Plasmodium falciparum
by: Minxi Li, et al.
Published: (2025-08-01)

Advances in transmission-blocking vaccines against Plasmodium falciparum and Plasmodium vivax
by: Mayumi Tachibana, et al.
Published: (2025-12-01)

Treatment outcomes of drug-resistant tuberculosis in Sabah, Malaysia – a retrospective cohort study
by: Y.L. Lew, et al.
Published: (2025-06-01)

Trend and Awareness of E-Cigarettes Among Students in a Private College in Sabah Malaysia
by: Vitalis Ronald Eden, et al.
Published: (2024-11-01)

The Tongkungon: A Traditional KadazanDusun Plucked Musical Instrument from Sabah, Malaysia
by: Sinin Hamdan, et al.
Published: (2024-11-01)

Effects of life history strategy on the diversity and composition of the coral holobiont communities of Sabah, Malaysia
by: Golam Rabbani, et al.
Published: (2025-02-01)

Impact of COVID-19 on dengue: a twofold challenge to public health in Sabah, Malaysia
by: Krishnan Nair Balakrishnan, et al.
Published: (2024-09-01)

One-Pot Synthesis and <i>In Vitro</i> Studies of Calix[4]-2-methylresorcinarene Derivatives as Antimalarial Agents Against <i>Plasmodium falciparum</i> Chloroquine-Resistant Strain FCR-3
by: Baiq Ike Nursofia, et al.
Published: (2024-12-01)

Inferring Strain Mixture within Clinical Plasmodium falciparum Isolates from Genomic Sequence Data.
by: John D O'Brien, et al.
Published: (2016-06-01)

Plasmodium falciparum malaria endemicity in Indonesia in 2010.
by: Iqbal R F Elyazar, et al.
Published: (2011-01-01)

The plasmepsin-piperaquine paradox persists in Plasmodium falciparum.
by: Breanna Walsh, et al.
Published: (2025-07-01)

Targeting the Plasmodium falciparum IspE Enzyme
by: Eleonora Diamanti, et al.
Published: (2024-10-01)

Therapeutic efficacy of Chloroquine for the treatment of uncomplicated Plasmodium vivax infection in Shewa Robit, Northeast Ethiopia.
by: Habtamu Belay, et al.
Published: (2023-01-01)

Modelling the incidence of Plasmodium vivax and Plasmodium falciparum malaria in Afghanistan 2006-2009.
by: Victor A Alegana, et al.
Published: (2014-01-01)

Short report: unmanned aerial vehicle for wide area larvicide spraying (WALS) using Vectobac® WG at Kota Kinabalu, Sabah
by: Michal Christina Steven, et al.
Published: (2024-02-01)