Ethanolic extract of Dayak onion (Eleutherine palmifolia) prevented sperm membran damage in mice exposed to monosodium glutamate
Monosodium glutamate (MSG) could cause increased production of reactive oxygen species (ROS), causing oxidative stress in the testicles, which adversely affected sperm quality. Dayak onion extract which is known for its high antioxidant content, could help alleviate oxidative stress caused by MSG. T...
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| Format: | Article |
| Language: | English |
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Universitas Airlangga
2024-11-01
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| Series: | Ovozoa: Journal of Animal Reproduction |
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| Online Access: | https://e-journal.unair.ac.id/OVZ/article/view/58289 |
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| author | Syahraini Adhiya Lathifah Aldin Akbar Rahmatullah Boedi Setiawan Chairul Anwar Nidom Nove Hidajati Sri Mulyati Tri Wahyu Suprayogi |
| author_facet | Syahraini Adhiya Lathifah Aldin Akbar Rahmatullah Boedi Setiawan Chairul Anwar Nidom Nove Hidajati Sri Mulyati Tri Wahyu Suprayogi |
| author_sort | Syahraini Adhiya Lathifah |
| collection | DOAJ |
| description | Monosodium glutamate (MSG) could cause increased production of reactive oxygen species (ROS), causing oxidative stress in the testicles, which adversely affected sperm quality. Dayak onion extract which is known for its high antioxidant content, could help alleviate oxidative stress caused by MSG. This research examined the effect of Dayak onion (Eleutherine palmifolia) on sperm abnormalities and plasma membrane integrity in mice (Mus musculus) exposed to MSG. Twenty-five male mice, 8 weeks old with a body weight approximately 20g, were divided into five groups, C– (received 0.5% Na-CMC), C+ (received 4 mg/g bw MSG), and three treatment groups (T1, T2, T3) which were given 4 mg/g bw MSG accompanied by Dayak onion extract at doses of 30, 60, and 120 mg/kg bw respectively. All treatments lasted for 52 days. Significant differences (p <0.05) in sperm abnormalities and plasma membrane integrity were observed among the groups. Sperm abnormalities found were (12.3 ± 1.92), (61.1 ± 3.10), (41.6 ± 2.87), (30.4± 1.91), and (18.2 ± 2.10) % respectively for C–, C+, T1, T2 and T3. Meanwhile, sperm plasma membrane integrity found were (33.0 ± 3.24), (69.3 ± 2.32), (41.8 ± 2.42), (55.4 ± 3.11), and (64.2 ± 1.27) % respectively for C–, C+, T1, T2 and T3. These results indicate that Dayak onion extract could help reduce sperm abnormalities and maintain plasma membrane integrity in mice exposed to MSG. |
| format | Article |
| id | doaj-art-46e610131d3a4553a6dad46490fc1a45 |
| institution | Kabale University |
| issn | 2302-6464 2722-967X |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Universitas Airlangga |
| record_format | Article |
| series | Ovozoa: Journal of Animal Reproduction |
| spelling | doaj-art-46e610131d3a4553a6dad46490fc1a452025-02-06T01:12:29ZengUniversitas AirlanggaOvozoa: Journal of Animal Reproduction2302-64642722-967X2024-11-0113315316010.20473/ovz.v13i3.2024.153-16056455Ethanolic extract of Dayak onion (Eleutherine palmifolia) prevented sperm membran damage in mice exposed to monosodium glutamateSyahraini Adhiya Lathifah0https://orcid.org/0009-0008-5117-2941Aldin Akbar Rahmatullah1https://orcid.org/0009-0004-2777-4177Boedi Setiawan2https://orcid.org/0000-0003-3721-4240Chairul Anwar Nidom3https://orcid.org/0000-0002-1513-7400Nove Hidajati4https://orcid.org/0000-0002-8769-5655Sri Mulyati5https://orcid.org/0000-0002-0193-4898Tri Wahyu Suprayogi6https://orcid.org/0000-0002-2366-5027Internship Vetrinarian at Department of Food Security, Agriculture and Fisheries of Cirebon Jl. Kalijaga No.173, Pegambiran, Kec. Lemahwungkuk, Cirebon City, West Java 45113, Indonesia Veterinarian in Aar Vet Clinic, Banjarbaru, South Kalimantan, IndonesiaDivision of Veterinary Clinic, Faculty of Veterinary Medicine, Universitas Airlangga, IndonesiaDivision of Basic Veterinary Medicine, Faculty of Veterinary Medicine Universitas Airlangga, IndonesiaDivision of Basic Veterinary Medicine, Faculty of Veterinary Medicine Universitas Airlangga, IndonesiaDivision of Veterinary Reproduction, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, IndonesiaDivision of Veterinary Reproduction, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, IndonesiaMonosodium glutamate (MSG) could cause increased production of reactive oxygen species (ROS), causing oxidative stress in the testicles, which adversely affected sperm quality. Dayak onion extract which is known for its high antioxidant content, could help alleviate oxidative stress caused by MSG. This research examined the effect of Dayak onion (Eleutherine palmifolia) on sperm abnormalities and plasma membrane integrity in mice (Mus musculus) exposed to MSG. Twenty-five male mice, 8 weeks old with a body weight approximately 20g, were divided into five groups, C– (received 0.5% Na-CMC), C+ (received 4 mg/g bw MSG), and three treatment groups (T1, T2, T3) which were given 4 mg/g bw MSG accompanied by Dayak onion extract at doses of 30, 60, and 120 mg/kg bw respectively. All treatments lasted for 52 days. Significant differences (p <0.05) in sperm abnormalities and plasma membrane integrity were observed among the groups. Sperm abnormalities found were (12.3 ± 1.92), (61.1 ± 3.10), (41.6 ± 2.87), (30.4± 1.91), and (18.2 ± 2.10) % respectively for C–, C+, T1, T2 and T3. Meanwhile, sperm plasma membrane integrity found were (33.0 ± 3.24), (69.3 ± 2.32), (41.8 ± 2.42), (55.4 ± 3.11), and (64.2 ± 1.27) % respectively for C–, C+, T1, T2 and T3. These results indicate that Dayak onion extract could help reduce sperm abnormalities and maintain plasma membrane integrity in mice exposed to MSG.https://e-journal.unair.ac.id/OVZ/article/view/58289dayak onionmicemsgreproductive healthsperm quality |
| spellingShingle | Syahraini Adhiya Lathifah Aldin Akbar Rahmatullah Boedi Setiawan Chairul Anwar Nidom Nove Hidajati Sri Mulyati Tri Wahyu Suprayogi Ethanolic extract of Dayak onion (Eleutherine palmifolia) prevented sperm membran damage in mice exposed to monosodium glutamate Ovozoa: Journal of Animal Reproduction dayak onion mice msg reproductive health sperm quality |
| title | Ethanolic extract of Dayak onion (Eleutherine palmifolia) prevented sperm membran damage in mice exposed to monosodium glutamate |
| title_full | Ethanolic extract of Dayak onion (Eleutherine palmifolia) prevented sperm membran damage in mice exposed to monosodium glutamate |
| title_fullStr | Ethanolic extract of Dayak onion (Eleutherine palmifolia) prevented sperm membran damage in mice exposed to monosodium glutamate |
| title_full_unstemmed | Ethanolic extract of Dayak onion (Eleutherine palmifolia) prevented sperm membran damage in mice exposed to monosodium glutamate |
| title_short | Ethanolic extract of Dayak onion (Eleutherine palmifolia) prevented sperm membran damage in mice exposed to monosodium glutamate |
| title_sort | ethanolic extract of dayak onion eleutherine palmifolia prevented sperm membran damage in mice exposed to monosodium glutamate |
| topic | dayak onion mice msg reproductive health sperm quality |
| url | https://e-journal.unair.ac.id/OVZ/article/view/58289 |
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