Oral acitretin treatment in severe congenital ichthyosis of the neonate
Two newborn infants with ichthyosis, one with lamellar ichthyosis and one with nonbullous ichthyosis form erythroderma, who presented at birth with a collodion baby appearance, were treated with acitretin (1 mg/kg/day). Clinical improvement was achieved shortly after treatment. The second cas...
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| Format: | Article |
| Language: | English |
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Hacettepe University Institute of Child Health
2002-01-01
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| Series: | The Turkish Journal of Pediatrics |
| Online Access: | https://turkjpediatr.org/article/view/2940 |
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| _version_ | 1850028846783397888 |
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| author | Z Nurhan Saraçoğlu Neslihan Tekin Selim M Urer Ilham Sabuncu Arif Akşit |
| author_facet | Z Nurhan Saraçoğlu Neslihan Tekin Selim M Urer Ilham Sabuncu Arif Akşit |
| author_sort | Z Nurhan Saraçoğlu |
| collection | DOAJ |
| description |
Two newborn infants with ichthyosis, one with lamellar ichthyosis and one with nonbullous ichthyosis form erythroderma, who presented at birth with a collodion baby appearance, were treated with acitretin (1 mg/kg/day). Clinical improvement was achieved shortly after treatment. The second case received oral retinoid for 3.5 months and was followed for nine months. The result was excellent. The treatment resulted in a satisfactory improvement in the skin condition of the first case. The tolerance to the drug was good. Side effects were not observed. It was concluded that early management of severe ichthyosis cases could prevent life-threatening events such as hyperthermia, disturbance in electrolyte and fluid balance, and infection.
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| format | Article |
| id | doaj-art-46e05edb56d44fb785d76896f4f4190e |
| institution | DOAJ |
| issn | 0041-4301 2791-6421 |
| language | English |
| publishDate | 2002-01-01 |
| publisher | Hacettepe University Institute of Child Health |
| record_format | Article |
| series | The Turkish Journal of Pediatrics |
| spelling | doaj-art-46e05edb56d44fb785d76896f4f4190e2025-08-20T02:59:42ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212002-01-01441Oral acitretin treatment in severe congenital ichthyosis of the neonateZ Nurhan Saraçoğlu0Neslihan TekinSelim M UrerIlham SabuncuArif AkşitDepartment of Dermatology, Osmangazi University Faculty of Medicine, Eskişehir, Turkey. Two newborn infants with ichthyosis, one with lamellar ichthyosis and one with nonbullous ichthyosis form erythroderma, who presented at birth with a collodion baby appearance, were treated with acitretin (1 mg/kg/day). Clinical improvement was achieved shortly after treatment. The second case received oral retinoid for 3.5 months and was followed for nine months. The result was excellent. The treatment resulted in a satisfactory improvement in the skin condition of the first case. The tolerance to the drug was good. Side effects were not observed. It was concluded that early management of severe ichthyosis cases could prevent life-threatening events such as hyperthermia, disturbance in electrolyte and fluid balance, and infection. https://turkjpediatr.org/article/view/2940 |
| spellingShingle | Z Nurhan Saraçoğlu Neslihan Tekin Selim M Urer Ilham Sabuncu Arif Akşit Oral acitretin treatment in severe congenital ichthyosis of the neonate The Turkish Journal of Pediatrics |
| title | Oral acitretin treatment in severe congenital ichthyosis of the neonate |
| title_full | Oral acitretin treatment in severe congenital ichthyosis of the neonate |
| title_fullStr | Oral acitretin treatment in severe congenital ichthyosis of the neonate |
| title_full_unstemmed | Oral acitretin treatment in severe congenital ichthyosis of the neonate |
| title_short | Oral acitretin treatment in severe congenital ichthyosis of the neonate |
| title_sort | oral acitretin treatment in severe congenital ichthyosis of the neonate |
| url | https://turkjpediatr.org/article/view/2940 |
| work_keys_str_mv | AT znurhansaracoglu oralacitretintreatmentinseverecongenitalichthyosisoftheneonate AT neslihantekin oralacitretintreatmentinseverecongenitalichthyosisoftheneonate AT selimmurer oralacitretintreatmentinseverecongenitalichthyosisoftheneonate AT ilhamsabuncu oralacitretintreatmentinseverecongenitalichthyosisoftheneonate AT arifaksit oralacitretintreatmentinseverecongenitalichthyosisoftheneonate |