Effects of pH on the Shape of Alginate Particles and Its Release Behavior

A vast majority of alginate particles exist as spheres in most practical uses, and both the particle shape and size are the key factors dominating the applications and performance of alginate gels. Therefore, it becomes an issue of great interest to investigate the aspheric alginate particles. As th...

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Main Authors: Jui-Jung Chuang, Yu-Ya Huang, Szu-Hsuan Lo, Tzu-Fang Hsu, Wen-Ying Huang, Shu-Ling Huang, Yung-Sheng Lin
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:International Journal of Polymer Science
Online Access:http://dx.doi.org/10.1155/2017/3902704
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author Jui-Jung Chuang
Yu-Ya Huang
Szu-Hsuan Lo
Tzu-Fang Hsu
Wen-Ying Huang
Shu-Ling Huang
Yung-Sheng Lin
author_facet Jui-Jung Chuang
Yu-Ya Huang
Szu-Hsuan Lo
Tzu-Fang Hsu
Wen-Ying Huang
Shu-Ling Huang
Yung-Sheng Lin
author_sort Jui-Jung Chuang
collection DOAJ
description A vast majority of alginate particles exist as spheres in most practical uses, and both the particle shape and size are the key factors dominating the applications and performance of alginate gels. Therefore, it becomes an issue of great interest to investigate the aspheric alginate particles. As the first step, various shaped alginate particles were formed due to various pH values in gelation solutions. It was experimentally demonstrated that a low pH brought about an oblate shape, and particularly lower concentrations of both alginate and divalent cations resulted in a flattened oblate shape. Ba2+ acting as a cross-linker had a less impact on the particle shape than Ca2+ due to a higher affinity in alginate intermolecular cross-linking. With a larger surface area, an oblate particle offered a higher release rate than a spheric one.
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publishDate 2017-01-01
publisher Wiley
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series International Journal of Polymer Science
spelling doaj-art-46d12798787d42e3a717d9d5dc7062522025-02-03T06:11:04ZengWileyInternational Journal of Polymer Science1687-94221687-94302017-01-01201710.1155/2017/39027043902704Effects of pH on the Shape of Alginate Particles and Its Release BehaviorJui-Jung Chuang0Yu-Ya Huang1Szu-Hsuan Lo2Tzu-Fang Hsu3Wen-Ying Huang4Shu-Ling Huang5Yung-Sheng Lin6Department of Pharmacy, Cheng Ching Hospital, Taichung, TaiwanDepartment of Applied Cosmetology and Master Program of Cosmetic Science, Hungkuang University, Taichung, TaiwanDepartment of Applied Cosmetology and Master Program of Cosmetic Science, Hungkuang University, Taichung, TaiwanDepartment of Applied Cosmetology and Master Program of Cosmetic Science, Hungkuang University, Taichung, TaiwanDepartment of Applied Cosmetology and Master Program of Cosmetic Science, Hungkuang University, Taichung, TaiwanDepartment of Chemical Engineering, National United University, Miaoli, TaiwanDepartment of Chemical Engineering, National United University, Miaoli, TaiwanA vast majority of alginate particles exist as spheres in most practical uses, and both the particle shape and size are the key factors dominating the applications and performance of alginate gels. Therefore, it becomes an issue of great interest to investigate the aspheric alginate particles. As the first step, various shaped alginate particles were formed due to various pH values in gelation solutions. It was experimentally demonstrated that a low pH brought about an oblate shape, and particularly lower concentrations of both alginate and divalent cations resulted in a flattened oblate shape. Ba2+ acting as a cross-linker had a less impact on the particle shape than Ca2+ due to a higher affinity in alginate intermolecular cross-linking. With a larger surface area, an oblate particle offered a higher release rate than a spheric one.http://dx.doi.org/10.1155/2017/3902704
spellingShingle Jui-Jung Chuang
Yu-Ya Huang
Szu-Hsuan Lo
Tzu-Fang Hsu
Wen-Ying Huang
Shu-Ling Huang
Yung-Sheng Lin
Effects of pH on the Shape of Alginate Particles and Its Release Behavior
International Journal of Polymer Science
title Effects of pH on the Shape of Alginate Particles and Its Release Behavior
title_full Effects of pH on the Shape of Alginate Particles and Its Release Behavior
title_fullStr Effects of pH on the Shape of Alginate Particles and Its Release Behavior
title_full_unstemmed Effects of pH on the Shape of Alginate Particles and Its Release Behavior
title_short Effects of pH on the Shape of Alginate Particles and Its Release Behavior
title_sort effects of ph on the shape of alginate particles and its release behavior
url http://dx.doi.org/10.1155/2017/3902704
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