Effects of pH on the Shape of Alginate Particles and Its Release Behavior
A vast majority of alginate particles exist as spheres in most practical uses, and both the particle shape and size are the key factors dominating the applications and performance of alginate gels. Therefore, it becomes an issue of great interest to investigate the aspheric alginate particles. As th...
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Format: | Article |
Language: | English |
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Wiley
2017-01-01
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Series: | International Journal of Polymer Science |
Online Access: | http://dx.doi.org/10.1155/2017/3902704 |
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author | Jui-Jung Chuang Yu-Ya Huang Szu-Hsuan Lo Tzu-Fang Hsu Wen-Ying Huang Shu-Ling Huang Yung-Sheng Lin |
author_facet | Jui-Jung Chuang Yu-Ya Huang Szu-Hsuan Lo Tzu-Fang Hsu Wen-Ying Huang Shu-Ling Huang Yung-Sheng Lin |
author_sort | Jui-Jung Chuang |
collection | DOAJ |
description | A vast majority of alginate particles exist as spheres in most practical uses, and both the particle shape and size are the key factors dominating the applications and performance of alginate gels. Therefore, it becomes an issue of great interest to investigate the aspheric alginate particles. As the first step, various shaped alginate particles were formed due to various pH values in gelation solutions. It was experimentally demonstrated that a low pH brought about an oblate shape, and particularly lower concentrations of both alginate and divalent cations resulted in a flattened oblate shape. Ba2+ acting as a cross-linker had a less impact on the particle shape than Ca2+ due to a higher affinity in alginate intermolecular cross-linking. With a larger surface area, an oblate particle offered a higher release rate than a spheric one. |
format | Article |
id | doaj-art-46d12798787d42e3a717d9d5dc706252 |
institution | Kabale University |
issn | 1687-9422 1687-9430 |
language | English |
publishDate | 2017-01-01 |
publisher | Wiley |
record_format | Article |
series | International Journal of Polymer Science |
spelling | doaj-art-46d12798787d42e3a717d9d5dc7062522025-02-03T06:11:04ZengWileyInternational Journal of Polymer Science1687-94221687-94302017-01-01201710.1155/2017/39027043902704Effects of pH on the Shape of Alginate Particles and Its Release BehaviorJui-Jung Chuang0Yu-Ya Huang1Szu-Hsuan Lo2Tzu-Fang Hsu3Wen-Ying Huang4Shu-Ling Huang5Yung-Sheng Lin6Department of Pharmacy, Cheng Ching Hospital, Taichung, TaiwanDepartment of Applied Cosmetology and Master Program of Cosmetic Science, Hungkuang University, Taichung, TaiwanDepartment of Applied Cosmetology and Master Program of Cosmetic Science, Hungkuang University, Taichung, TaiwanDepartment of Applied Cosmetology and Master Program of Cosmetic Science, Hungkuang University, Taichung, TaiwanDepartment of Applied Cosmetology and Master Program of Cosmetic Science, Hungkuang University, Taichung, TaiwanDepartment of Chemical Engineering, National United University, Miaoli, TaiwanDepartment of Chemical Engineering, National United University, Miaoli, TaiwanA vast majority of alginate particles exist as spheres in most practical uses, and both the particle shape and size are the key factors dominating the applications and performance of alginate gels. Therefore, it becomes an issue of great interest to investigate the aspheric alginate particles. As the first step, various shaped alginate particles were formed due to various pH values in gelation solutions. It was experimentally demonstrated that a low pH brought about an oblate shape, and particularly lower concentrations of both alginate and divalent cations resulted in a flattened oblate shape. Ba2+ acting as a cross-linker had a less impact on the particle shape than Ca2+ due to a higher affinity in alginate intermolecular cross-linking. With a larger surface area, an oblate particle offered a higher release rate than a spheric one.http://dx.doi.org/10.1155/2017/3902704 |
spellingShingle | Jui-Jung Chuang Yu-Ya Huang Szu-Hsuan Lo Tzu-Fang Hsu Wen-Ying Huang Shu-Ling Huang Yung-Sheng Lin Effects of pH on the Shape of Alginate Particles and Its Release Behavior International Journal of Polymer Science |
title | Effects of pH on the Shape of Alginate Particles and Its Release Behavior |
title_full | Effects of pH on the Shape of Alginate Particles and Its Release Behavior |
title_fullStr | Effects of pH on the Shape of Alginate Particles and Its Release Behavior |
title_full_unstemmed | Effects of pH on the Shape of Alginate Particles and Its Release Behavior |
title_short | Effects of pH on the Shape of Alginate Particles and Its Release Behavior |
title_sort | effects of ph on the shape of alginate particles and its release behavior |
url | http://dx.doi.org/10.1155/2017/3902704 |
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