Is self-report sleepiness associated with cognitive performance in temporal lobe epilepsy?

ABSTRACT Sleepiness and cognitive impairment are common symptoms observed in patients with epilepsy. We investigate whether self-reported sleepiness is associated with cognitive performance in patients with refractory mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS). Seventy-one co...

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Main Authors: Helena Dresch Vascouto, Maria Emília Rodrigues de Oliveira Thais, Camila Moreira Osório, Juliana Ben, Lucia Sukys Claudino, Alexandre Ademar Hoeller, Hans J. Markowitsch, Peter Wolf, Katia Lin, Roger Walz
Format: Article
Language:English
Published: Thieme Revinter Publicações
Series:Arquivos de Neuro-Psiquiatria
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2018000900575&lng=en&tlng=en
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author Helena Dresch Vascouto
Maria Emília Rodrigues de Oliveira Thais
Camila Moreira Osório
Juliana Ben
Lucia Sukys Claudino
Alexandre Ademar Hoeller
Hans J. Markowitsch
Peter Wolf
Katia Lin
Roger Walz
author_facet Helena Dresch Vascouto
Maria Emília Rodrigues de Oliveira Thais
Camila Moreira Osório
Juliana Ben
Lucia Sukys Claudino
Alexandre Ademar Hoeller
Hans J. Markowitsch
Peter Wolf
Katia Lin
Roger Walz
author_sort Helena Dresch Vascouto
collection DOAJ
description ABSTRACT Sleepiness and cognitive impairment are common symptoms observed in patients with epilepsy. We investigate whether self-reported sleepiness is associated with cognitive performance in patients with refractory mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS). Seventy-one consecutive patients with MTLE-HS were evaluated with the Stanford Sleepiness Scale (SSS) before neuropsychological evaluation. Their mean SSS scores were compared with controls. Each cognitive test was compared between patients with (SSS ≥ 3) or without sleepiness (SSS < 3). Imbalances were controlled by regression analysis. Patients reported a significantly higher degree of sleepiness than controls (p < 0.0001). After multiple linear regression analysis, only one test (RAVLT total) remained associated with self-reported sleepiness. Conclusion: Self-reported sleepiness was significantly higher in MTLE-HS patients than controls, but did not affect their cognitive performance. If confirmed in other populations, our results may have implications for decision making about sleepiness screening in neuropsychological settings.
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institution OA Journals
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publisher Thieme Revinter Publicações
record_format Article
series Arquivos de Neuro-Psiquiatria
spelling doaj-art-46ccbe25d4a94679a2a8e5bf5d5f2af12025-08-20T01:56:34ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-422776957558110.1590/0004-282x20180089S0004-282X2018000900575Is self-report sleepiness associated with cognitive performance in temporal lobe epilepsy?Helena Dresch VascoutoMaria Emília Rodrigues de Oliveira ThaisCamila Moreira OsórioJuliana BenLucia Sukys ClaudinoAlexandre Ademar HoellerHans J. MarkowitschPeter WolfKatia LinRoger WalzABSTRACT Sleepiness and cognitive impairment are common symptoms observed in patients with epilepsy. We investigate whether self-reported sleepiness is associated with cognitive performance in patients with refractory mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS). Seventy-one consecutive patients with MTLE-HS were evaluated with the Stanford Sleepiness Scale (SSS) before neuropsychological evaluation. Their mean SSS scores were compared with controls. Each cognitive test was compared between patients with (SSS ≥ 3) or without sleepiness (SSS < 3). Imbalances were controlled by regression analysis. Patients reported a significantly higher degree of sleepiness than controls (p < 0.0001). After multiple linear regression analysis, only one test (RAVLT total) remained associated with self-reported sleepiness. Conclusion: Self-reported sleepiness was significantly higher in MTLE-HS patients than controls, but did not affect their cognitive performance. If confirmed in other populations, our results may have implications for decision making about sleepiness screening in neuropsychological settings.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2018000900575&lng=en&tlng=enneuropsychological testsdrug resistant epilepsyclinical decision-making
spellingShingle Helena Dresch Vascouto
Maria Emília Rodrigues de Oliveira Thais
Camila Moreira Osório
Juliana Ben
Lucia Sukys Claudino
Alexandre Ademar Hoeller
Hans J. Markowitsch
Peter Wolf
Katia Lin
Roger Walz
Is self-report sleepiness associated with cognitive performance in temporal lobe epilepsy?
Arquivos de Neuro-Psiquiatria
neuropsychological tests
drug resistant epilepsy
clinical decision-making
title Is self-report sleepiness associated with cognitive performance in temporal lobe epilepsy?
title_full Is self-report sleepiness associated with cognitive performance in temporal lobe epilepsy?
title_fullStr Is self-report sleepiness associated with cognitive performance in temporal lobe epilepsy?
title_full_unstemmed Is self-report sleepiness associated with cognitive performance in temporal lobe epilepsy?
title_short Is self-report sleepiness associated with cognitive performance in temporal lobe epilepsy?
title_sort is self report sleepiness associated with cognitive performance in temporal lobe epilepsy
topic neuropsychological tests
drug resistant epilepsy
clinical decision-making
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2018000900575&lng=en&tlng=en
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