Electroacupuncture combined with HDAC1 inhibitor suppress tumor growth via improving the recruitment of intratumor CD8+ T cells for triple-negative breast cancer in mice

Electroacupuncture combined with HDAC1 inhibitor suppress tumor growth via improving the recruitment of intratumor CD8+ T cells for triple-negative breast cancer in mice

Triple-negative breast cancer (TNBC) is known for its aggressive nature and poor prognosis, primarily due to limited treatment options stemming from immune evasion mechanisms. This study aimed to explore the therapeutic potential of peritumoral electroacupuncture (EA) in inhibiting tumor growth in T...

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Bibliographic Details
Main Authors: Yehong Tian, Yinjie Ma, Xue Li, Gang Lu, Shixin Wang, Xiaowei Qiu, Xu Du
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Oncology
Subjects:
electroacupuncture
triple-negative breast cancer
histone deacetylase 1
CCL5
CD8+ T cells
tumor microenvironment
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1584722/full
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