Bidirectional two-sample Mendelian randomization reveals causal link between genetic blood metabolites and tuberculosis

Bidirectional two-sample Mendelian randomization reveals causal link between genetic blood metabolites and tuberculosis

Abstract Tuberculosis (TB), caused by infectious agent Mycobacterium tuberculosis (Mtb) seriously poses a great threat to health. An array of metabolites generated by metabolic pathways are essential for Mtb pathophysiology. However, a specific causal relationship between TB and human metabolites re...

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Bibliographic Details
Main Authors: Zhenyu Shi, Chenyi Zhao, Xiaowen Yu, Dingding Zhao, Yongqiang Li
Format: Article
Language:English
Published: SpringerOpen 2025-06-01
Series:AMB Express
Subjects:
Mendelian randomization
TB
Metabolites
Casual effect
Online Access:https://doi.org/10.1186/s13568-025-01901-w
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