Alaninaminotransferase and specific viral hepatitis markers in the blood of donors

Aim of investigation. To study the dynamics of viral hepatitis detection rate after implementation of donors preliminary testing for alanine aminotransferase (ALT) activity. Material and methods. Viral hepatitis markers detection rate by immuno-chemiluminescence assay at testing for ALT activity in...

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Main Authors: Zh. K. Burkitbayev, G. A. Yesenbayeva, S. A. Abdrakhmanova, Zh. Zh. Bibekov, Ye. B. Zhiburt
Format: Article
Language:Russian
Published: Gastro LLC 2018-08-01
Series:Российский журнал гастроэнтерологии, гепатологии, колопроктологии
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Online Access:https://www.gastro-j.ru/jour/article/view/217
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author Zh. K. Burkitbayev
G. A. Yesenbayeva
S. A. Abdrakhmanova
Zh. Zh. Bibekov
Ye. B. Zhiburt
author_facet Zh. K. Burkitbayev
G. A. Yesenbayeva
S. A. Abdrakhmanova
Zh. Zh. Bibekov
Ye. B. Zhiburt
author_sort Zh. K. Burkitbayev
collection DOAJ
description Aim of investigation. To study the dynamics of viral hepatitis detection rate after implementation of donors preliminary testing for alanine aminotransferase (ALT) activity. Material and methods. Viral hepatitis markers detection rate by immuno-chemiluminescence assay at testing for ALT activity in venous (n=47080) and capillary (n=22530) blood of donors was studied. Results. Males had higher ALT activity in comparison to that in females, both in venous (for 54.1%), and in capillary (for 27.2%) blood. ALT capillary blood activity was higher on the average, than in venous, for 10.1% in men and 33.3% in women. Conclusions. ALT activity elevation is associated by twofold increase in the rate of lacteous serum and more frequent detection of hepatitis serological markers. In the samples received after capillary blood culling the anti-hepatitis C virus antibodies positivity rate was decreased. No relation of ALT activity to results of parenteral virus genomes screen was revealed.
format Article
id doaj-art-46c2d3845c754849acdca54944b8c56d
institution Kabale University
issn 1382-4376
2658-6673
language Russian
publishDate 2018-08-01
publisher Gastro LLC
record_format Article
series Российский журнал гастроэнтерологии, гепатологии, колопроктологии
spelling doaj-art-46c2d3845c754849acdca54944b8c56d2025-02-10T16:14:29ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732018-08-01281505410.22416/1382-4376-2018-28-1-50-54217Alaninaminotransferase and specific viral hepatitis markers in the blood of donorsZh. K. Burkitbayev0G. A. Yesenbayeva1S. A. Abdrakhmanova2Zh. Zh. Bibekov3Ye. B. Zhiburt4Republican state enterprise with the right of economic management «Scientific-Production Center of Transfusiology»Republican state enterprise with the right of economic management «Scientific-Production Center of Transfusiology»Republican state enterprise with the right of economic management «Scientific-Production Center of Transfusiology»Republican state enterprise with the right of economic management «Scientific-Production Center of Transfusiology»Federal state government-financed institution «Pirogov National Medical and Surgical Center»Aim of investigation. To study the dynamics of viral hepatitis detection rate after implementation of donors preliminary testing for alanine aminotransferase (ALT) activity. Material and methods. Viral hepatitis markers detection rate by immuno-chemiluminescence assay at testing for ALT activity in venous (n=47080) and capillary (n=22530) blood of donors was studied. Results. Males had higher ALT activity in comparison to that in females, both in venous (for 54.1%), and in capillary (for 27.2%) blood. ALT capillary blood activity was higher on the average, than in venous, for 10.1% in men and 33.3% in women. Conclusions. ALT activity elevation is associated by twofold increase in the rate of lacteous serum and more frequent detection of hepatitis serological markers. In the samples received after capillary blood culling the anti-hepatitis C virus antibodies positivity rate was decreased. No relation of ALT activity to results of parenteral virus genomes screen was revealed.https://www.gastro-j.ru/jour/article/view/217маркеры вирусных гепатитовактивность аланинаминотрансферазыхилез
spellingShingle Zh. K. Burkitbayev
G. A. Yesenbayeva
S. A. Abdrakhmanova
Zh. Zh. Bibekov
Ye. B. Zhiburt
Alaninaminotransferase and specific viral hepatitis markers in the blood of donors
Российский журнал гастроэнтерологии, гепатологии, колопроктологии
маркеры вирусных гепатитов
активность аланинаминотрансферазы
хилез
title Alaninaminotransferase and specific viral hepatitis markers in the blood of donors
title_full Alaninaminotransferase and specific viral hepatitis markers in the blood of donors
title_fullStr Alaninaminotransferase and specific viral hepatitis markers in the blood of donors
title_full_unstemmed Alaninaminotransferase and specific viral hepatitis markers in the blood of donors
title_short Alaninaminotransferase and specific viral hepatitis markers in the blood of donors
title_sort alaninaminotransferase and specific viral hepatitis markers in the blood of donors
topic маркеры вирусных гепатитов
активность аланинаминотрансферазы
хилез
url https://www.gastro-j.ru/jour/article/view/217
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AT gayesenbayeva alaninaminotransferaseandspecificviralhepatitismarkersinthebloodofdonors
AT saabdrakhmanova alaninaminotransferaseandspecificviralhepatitismarkersinthebloodofdonors
AT zhzhbibekov alaninaminotransferaseandspecificviralhepatitismarkersinthebloodofdonors
AT yebzhiburt alaninaminotransferaseandspecificviralhepatitismarkersinthebloodofdonors