Integrating Immunotherapy With Targeted Therapy: Evaluating Efficacy in NSCLC Treatment Through Computational Analysis of Gene Regulatory Networks

Non-Small Cell Lung Cancer (NSCLC) remains a leading cause of cancer-related deaths, often characterized by complex mutational landscapes and resistance to monotherapies. To address this, we developed a novel Boolean network (BN) model that integrates oncogenic and immunotherapy signaling pathways t...

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Bibliographic Details
Main Authors: Pranabesh Bhattacharjee, Aditya Lahiri, Tanmay Sindhwani, Norman Peter Reeves, Aniruddha Datta
Format: Article
Language:English
Published: IEEE 2025-01-01
Series:IEEE Access
Subjects:
Online Access:https://ieeexplore.ieee.org/document/11072162/
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