Reactive thrombocytosis in children

The aim of this study was to evaluate the causes of thrombocytosis, which was defined as a platelet count greater than 500 x 10(9)/L, and to compare the groups with mild and severe thrombocytosis. A total of 484 patients were evaluated for the etiology of thrombocytosis. Patients with a plate...

Full description

Saved in:
Bibliographic Details
Main Authors: Celal Özcan, Tülin Revide Şaylı, Vildan Koşan-Çulha
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 2013-08-01
Series:The Turkish Journal of Pediatrics
Online Access:https://turkjpediatr.org/article/view/1523
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850042900432289792
author Celal Özcan
Tülin Revide Şaylı
Vildan Koşan-Çulha
author_facet Celal Özcan
Tülin Revide Şaylı
Vildan Koşan-Çulha
author_sort Celal Özcan
collection DOAJ
description The aim of this study was to evaluate the causes of thrombocytosis, which was defined as a platelet count greater than 500 x 10(9)/L, and to compare the groups with mild and severe thrombocytosis. A total of 484 patients were evaluated for the etiology of thrombocytosis. Patients with a platelet count between 500-800 x 10(9)/L were considered to have mild thrombocytosis, while those with a count of ≥800 x 10(9)/L were considered as having severe thrombocytosis. Of 484 patients included, 63% had thrombocytosis due to an infectious disease, 11.4% had a chronic inflammatory condition, 8.5% had anemia, and 5.2% had tissue injury. The frequency of chronic inflammation was higher in the severe thrombocytosis group compared to the mild thrombocytosis group (p=0.006). In conclusion, severe infections and chronic inflammatory conditions should be considered in the differential diagnosis of a patient with severe thrombocytosis.
format Article
id doaj-art-46bde23f78004ca1a3dff45c8013ea56
institution DOAJ
issn 0041-4301
2791-6421
language English
publishDate 2013-08-01
publisher Hacettepe University Institute of Child Health
record_format Article
series The Turkish Journal of Pediatrics
spelling doaj-art-46bde23f78004ca1a3dff45c8013ea562025-08-20T02:55:23ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212013-08-01554Reactive thrombocytosis in childrenCelal Özcan0Tülin Revide ŞaylıVildan Koşan-ÇulhaDepartment of Pediatrics, Ankara Children's Hematology Oncology Training and Research Hospital, Ankara, Turkey. celalozcan01@yahoo.com.tr. The aim of this study was to evaluate the causes of thrombocytosis, which was defined as a platelet count greater than 500 x 10(9)/L, and to compare the groups with mild and severe thrombocytosis. A total of 484 patients were evaluated for the etiology of thrombocytosis. Patients with a platelet count between 500-800 x 10(9)/L were considered to have mild thrombocytosis, while those with a count of ≥800 x 10(9)/L were considered as having severe thrombocytosis. Of 484 patients included, 63% had thrombocytosis due to an infectious disease, 11.4% had a chronic inflammatory condition, 8.5% had anemia, and 5.2% had tissue injury. The frequency of chronic inflammation was higher in the severe thrombocytosis group compared to the mild thrombocytosis group (p=0.006). In conclusion, severe infections and chronic inflammatory conditions should be considered in the differential diagnosis of a patient with severe thrombocytosis. https://turkjpediatr.org/article/view/1523
spellingShingle Celal Özcan
Tülin Revide Şaylı
Vildan Koşan-Çulha
Reactive thrombocytosis in children
The Turkish Journal of Pediatrics
title Reactive thrombocytosis in children
title_full Reactive thrombocytosis in children
title_fullStr Reactive thrombocytosis in children
title_full_unstemmed Reactive thrombocytosis in children
title_short Reactive thrombocytosis in children
title_sort reactive thrombocytosis in children
url https://turkjpediatr.org/article/view/1523
work_keys_str_mv AT celalozcan reactivethrombocytosisinchildren
AT tulinrevidesaylı reactivethrombocytosisinchildren
AT vildankosanculha reactivethrombocytosisinchildren