Medical treatment of acquired uterine arteriovenous fistulae related to pregnancy: 2 case reports and literature review

Uterine arteriovenous fistula (UAVF) is a rare form of uterine arteriovenous malformation, the most characteristic clinical symptom of which is intermittent vaginal bleeding. Currently, reports on the treatment of UAVF mainly focus on uterine artery embolization (UAE), high-intensity focused ultraso...

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Main Authors: Lingna Huang, Lini Qiu, Jinwen Zhang, Hui Ye, Xiumei Xiong
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1584099/full
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author Lingna Huang
Lini Qiu
Jinwen Zhang
Hui Ye
Xiumei Xiong
author_facet Lingna Huang
Lini Qiu
Jinwen Zhang
Hui Ye
Xiumei Xiong
author_sort Lingna Huang
collection DOAJ
description Uterine arteriovenous fistula (UAVF) is a rare form of uterine arteriovenous malformation, the most characteristic clinical symptom of which is intermittent vaginal bleeding. Currently, reports on the treatment of UAVF mainly focus on uterine artery embolization (UAE), high-intensity focused ultrasound (HIFU), and surgical treatment, with relatively few reports on medical conservative therapy. This article reports the process and outcomes of medical treatment for two cases of pregnancy-related acquired UAVF and summarizes and analyzes the indications and drug selection for UAVF medical conservative treatment based on the relevant literature.
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institution Kabale University
issn 2296-858X
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publishDate 2025-08-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Medicine
spelling doaj-art-46ba17a76b234b19bbffb64518e4009b2025-08-20T03:39:10ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-08-011210.3389/fmed.2025.15840991584099Medical treatment of acquired uterine arteriovenous fistulae related to pregnancy: 2 case reports and literature reviewLingna Huang0Lini Qiu1Jinwen Zhang2Hui Ye3Xiumei Xiong4Department of Gynecology and Onbstetrics, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, Fujian, ChinaDepartment of Gynecology and Onbstetrics, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, Fujian, ChinaSchool of Basic Medicine Sciences, Fujian Medical University, Fuzhou, Fujian, ChinaDepartment of Gynecology and Onbstetrics, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, Fujian, ChinaDepartment of Gynecology and Onbstetrics, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, Fujian, ChinaUterine arteriovenous fistula (UAVF) is a rare form of uterine arteriovenous malformation, the most characteristic clinical symptom of which is intermittent vaginal bleeding. Currently, reports on the treatment of UAVF mainly focus on uterine artery embolization (UAE), high-intensity focused ultrasound (HIFU), and surgical treatment, with relatively few reports on medical conservative therapy. This article reports the process and outcomes of medical treatment for two cases of pregnancy-related acquired UAVF and summarizes and analyzes the indications and drug selection for UAVF medical conservative treatment based on the relevant literature.https://www.frontiersin.org/articles/10.3389/fmed.2025.1584099/fulluterine arteriovenous fistulapregnancy-relatedmedical treatmentPSVprogesteroneGnRH-a
spellingShingle Lingna Huang
Lini Qiu
Jinwen Zhang
Hui Ye
Xiumei Xiong
Medical treatment of acquired uterine arteriovenous fistulae related to pregnancy: 2 case reports and literature review
Frontiers in Medicine
uterine arteriovenous fistula
pregnancy-related
medical treatment
PSV
progesterone
GnRH-a
title Medical treatment of acquired uterine arteriovenous fistulae related to pregnancy: 2 case reports and literature review
title_full Medical treatment of acquired uterine arteriovenous fistulae related to pregnancy: 2 case reports and literature review
title_fullStr Medical treatment of acquired uterine arteriovenous fistulae related to pregnancy: 2 case reports and literature review
title_full_unstemmed Medical treatment of acquired uterine arteriovenous fistulae related to pregnancy: 2 case reports and literature review
title_short Medical treatment of acquired uterine arteriovenous fistulae related to pregnancy: 2 case reports and literature review
title_sort medical treatment of acquired uterine arteriovenous fistulae related to pregnancy 2 case reports and literature review
topic uterine arteriovenous fistula
pregnancy-related
medical treatment
PSV
progesterone
GnRH-a
url https://www.frontiersin.org/articles/10.3389/fmed.2025.1584099/full
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AT jinwenzhang medicaltreatmentofacquireduterinearteriovenousfistulaerelatedtopregnancy2casereportsandliteraturereview
AT huiye medicaltreatmentofacquireduterinearteriovenousfistulaerelatedtopregnancy2casereportsandliteraturereview
AT xiumeixiong medicaltreatmentofacquireduterinearteriovenousfistulaerelatedtopregnancy2casereportsandliteraturereview