Network-based investigation of petroleum hydrocarbons-induced ecotoxicological effects and their risk assessment
Petroleum hydrocarbons (PHs) are compounds composed mostly of carbon and hydrogen, originating from crude oil and its derivatives. PHs are primarily released into the environment through the diffusion of oils, resulting from anthropogenic activities like transportation and offshore drilling, and acc...
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| Language: | English |
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Elsevier
2024-12-01
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| Series: | Environment International |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0160412024007499 |
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| author | Ajaya Kumar Sahoo Shreyes Rajan Madgaonkar Nikhil Chivukula Panneerselvam Karthikeyan Kundhanathan Ramesh Shambanagouda Rudragouda Marigoudar Krishna Venkatarama Sharma Areejit Samal |
| author_facet | Ajaya Kumar Sahoo Shreyes Rajan Madgaonkar Nikhil Chivukula Panneerselvam Karthikeyan Kundhanathan Ramesh Shambanagouda Rudragouda Marigoudar Krishna Venkatarama Sharma Areejit Samal |
| author_sort | Ajaya Kumar Sahoo |
| collection | DOAJ |
| description | Petroleum hydrocarbons (PHs) are compounds composed mostly of carbon and hydrogen, originating from crude oil and its derivatives. PHs are primarily released into the environment through the diffusion of oils, resulting from anthropogenic activities like transportation and offshore drilling, and accidental incidents such as oil spills. Once released, these PHs can persist in different ecosystems and cause long-term detrimental ecological impacts. While the hazards associated with such PH contaminations are often assessed by the concentrations of total petroleum hydrocarbons in the environment, studies focusing on the risks associated with individual PHs are limited. In this study, different network-based frameworks were utilized to explore and understand the adverse ecological effects associated with PH exposure. First, a list of 320 PHs was systematically curated from published reports. Next, biological endpoint data from toxicological databases was systematically integrated, and a stressor-centric adverse outcome pathway (AOP) network, linking 75 PHs with 177 ecotoxicologically-relevant high confidence AOPs within AOP-Wiki, was constructed. Further, stressor-species networks, based on reported toxicity concentrations and bioconcentration factors data within ECOTOX, were constructed for 80 PHs and 28 PHs, respectively. It was found that crustaceans are documented to be affected by many of these PHs. Finally, the aquatic toxicity data within ECOTOX was used to construct species sensitivity distributions for PHs, and their corresponding hazard concentrations (HC05), that are harmful to 5% of species in the aquatic ecosystem, were derived. Further, the predicted no-effect concentrations (PNECs) and risk quotients for the US EPA priority polycyclic aromatic hydrocarbons (PAHs) were computed by using their environmental concentration data for Indian coastal and river waters. Overall, this study highlights the importance of using network-based approaches and risk assessment methods to understand the PH-induced toxicities effectively. |
| format | Article |
| id | doaj-art-46b784dfc35245e093bbeb32add6f834 |
| institution | DOAJ |
| issn | 0160-4120 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Environment International |
| spelling | doaj-art-46b784dfc35245e093bbeb32add6f8342025-08-20T02:52:26ZengElsevierEnvironment International0160-41202024-12-0119410916310.1016/j.envint.2024.109163Network-based investigation of petroleum hydrocarbons-induced ecotoxicological effects and their risk assessmentAjaya Kumar Sahoo0Shreyes Rajan Madgaonkar1Nikhil Chivukula2Panneerselvam Karthikeyan3Kundhanathan Ramesh4Shambanagouda Rudragouda Marigoudar5Krishna Venkatarama Sharma6Areejit Samal7The Institute of Mathematical Sciences (IMSc), Chennai, India; Homi Bhabha National Institute (HBNI), Mumbai, IndiaThe Institute of Mathematical Sciences (IMSc), Chennai, India; Homi Bhabha National Institute (HBNI), Mumbai, IndiaThe Institute of Mathematical Sciences (IMSc), Chennai, India; Homi Bhabha National Institute (HBNI), Mumbai, IndiaNational Centre for Coastal Research, Ministry of Earth Sciences, Government of India, Pallikaranai, Chennai, IndiaThe Institute of Mathematical Sciences (IMSc), Chennai, IndiaNational Centre for Coastal Research, Ministry of Earth Sciences, Government of India, Pallikaranai, Chennai, IndiaNational Centre for Coastal Research, Ministry of Earth Sciences, Government of India, Pallikaranai, Chennai, IndiaThe Institute of Mathematical Sciences (IMSc), Chennai, India; Homi Bhabha National Institute (HBNI), Mumbai, India; Corresponding author at: Computational Biology Group, The Institute of Mathematical Sciences (IMSc), CIT Campus, Taramani, Chennai 600113 India.Petroleum hydrocarbons (PHs) are compounds composed mostly of carbon and hydrogen, originating from crude oil and its derivatives. PHs are primarily released into the environment through the diffusion of oils, resulting from anthropogenic activities like transportation and offshore drilling, and accidental incidents such as oil spills. Once released, these PHs can persist in different ecosystems and cause long-term detrimental ecological impacts. While the hazards associated with such PH contaminations are often assessed by the concentrations of total petroleum hydrocarbons in the environment, studies focusing on the risks associated with individual PHs are limited. In this study, different network-based frameworks were utilized to explore and understand the adverse ecological effects associated with PH exposure. First, a list of 320 PHs was systematically curated from published reports. Next, biological endpoint data from toxicological databases was systematically integrated, and a stressor-centric adverse outcome pathway (AOP) network, linking 75 PHs with 177 ecotoxicologically-relevant high confidence AOPs within AOP-Wiki, was constructed. Further, stressor-species networks, based on reported toxicity concentrations and bioconcentration factors data within ECOTOX, were constructed for 80 PHs and 28 PHs, respectively. It was found that crustaceans are documented to be affected by many of these PHs. Finally, the aquatic toxicity data within ECOTOX was used to construct species sensitivity distributions for PHs, and their corresponding hazard concentrations (HC05), that are harmful to 5% of species in the aquatic ecosystem, were derived. Further, the predicted no-effect concentrations (PNECs) and risk quotients for the US EPA priority polycyclic aromatic hydrocarbons (PAHs) were computed by using their environmental concentration data for Indian coastal and river waters. Overall, this study highlights the importance of using network-based approaches and risk assessment methods to understand the PH-induced toxicities effectively.http://www.sciencedirect.com/science/article/pii/S0160412024007499Petroleum hydrocarbonsAdverse outcome pathwayStressor-AOP networkStressor-species networkEcological risk assessmentSpecies sensitivity distribution |
| spellingShingle | Ajaya Kumar Sahoo Shreyes Rajan Madgaonkar Nikhil Chivukula Panneerselvam Karthikeyan Kundhanathan Ramesh Shambanagouda Rudragouda Marigoudar Krishna Venkatarama Sharma Areejit Samal Network-based investigation of petroleum hydrocarbons-induced ecotoxicological effects and their risk assessment Environment International Petroleum hydrocarbons Adverse outcome pathway Stressor-AOP network Stressor-species network Ecological risk assessment Species sensitivity distribution |
| title | Network-based investigation of petroleum hydrocarbons-induced ecotoxicological effects and their risk assessment |
| title_full | Network-based investigation of petroleum hydrocarbons-induced ecotoxicological effects and their risk assessment |
| title_fullStr | Network-based investigation of petroleum hydrocarbons-induced ecotoxicological effects and their risk assessment |
| title_full_unstemmed | Network-based investigation of petroleum hydrocarbons-induced ecotoxicological effects and their risk assessment |
| title_short | Network-based investigation of petroleum hydrocarbons-induced ecotoxicological effects and their risk assessment |
| title_sort | network based investigation of petroleum hydrocarbons induced ecotoxicological effects and their risk assessment |
| topic | Petroleum hydrocarbons Adverse outcome pathway Stressor-AOP network Stressor-species network Ecological risk assessment Species sensitivity distribution |
| url | http://www.sciencedirect.com/science/article/pii/S0160412024007499 |
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