Gastrodin inhibits reactive astrocyte-mediated inflammation in hypoxic-ischemic brain damage through S100B/RAGE-Smad3 signaling

Activated astrocytes and their associated inflammatory responses play critical roles in the pathogenesis of hypoxic-ischemic brain damage (HIBD). Gastrodin (GAS), an anti-inflammatory herbal agent, is known to suppress microglial activation. Here, we investigate whether it exerts a similar effect on...

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Bibliographic Details
Main Authors: Wang Pengxiang, Zuo Hanjun, Shi Haolong, Wang Zhao, Ren Xueqi, Shi Jinsha, Guo Tao, Kuang Xianfeng, Zhao Min, Li Jinghui, Li Juanjuan
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2025-03-01
Series:Acta Biochimica et Biophysica Sinica
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Online Access:https://www.sciengine.com/doi/10.3724/abbs.2024235
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