Assessment of Leakage Radiation and Radiobiological Impacts in Gamma Knife Radiosurgery
Gamma Knife radiosurgery is a non-invasive radiotherapy technique for brain lesions. However, radiation leakage from collimators and high-dose exposure may alter blood parameters, potentially increasing the risk of secondary cancers and other complications. The purpose of this study is to measure t...
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Koya University
2025-06-01
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| Series: | ARO-The Scientific Journal of Koya University |
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| Online Access: | https://aro.koyauniversity.org/index.php/aro/article/view/2194 |
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| author | Bazhdar N. Mohammed Asaad H. Ismail Edrees M. Tahir |
| author_facet | Bazhdar N. Mohammed Asaad H. Ismail Edrees M. Tahir |
| author_sort | Bazhdar N. Mohammed |
| collection | DOAJ |
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Gamma Knife radiosurgery is a non-invasive radiotherapy technique for brain lesions. However, radiation leakage from collimators and high-dose exposure may alter blood parameters, potentially increasing the risk of secondary cancers and other complications. The purpose of this study is to measure the leakage radiation produced during trigeminal neuralgia and meningiomas lesion treatments and impact on various radiosensitive organs. In addition, the radiobiological impact on patients’ blood parameters is investigated for both short-term and long-term treatment exposure. Scatter radiation was measured using dosimeters placed at various body regions. Blood samples were collected from 20 patients at three different times. Changes in parameters were statistically analyzed using one-way analysis of variance, to assess significant differences across the time points. The highest scatter radiation levels were recorded at the face and neck significantly exceeding other body regions about 110 μSv and 350 μSv, respectively. Statistical analysis revealed that long-term exposure (58.2 min at 80 Gy) in trigeminal neuralgia cases resulted in significantly greater blood parameter changes (p ≤ 0.05) compared to short-term exposure (19.4 min at 20 Gy) in meningiomas. These findings reveal dose-dependent blood changes and highlight the importance of radiation protection measures to enhance patient safety, particularly during high-dose treatments.
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| format | Article |
| id | doaj-art-46b49deb476847c5a6a9c8d7afdb153d |
| institution | Kabale University |
| issn | 2410-9355 2307-549X |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Koya University |
| record_format | Article |
| series | ARO-The Scientific Journal of Koya University |
| spelling | doaj-art-46b49deb476847c5a6a9c8d7afdb153d2025-08-20T03:27:10ZengKoya UniversityARO-The Scientific Journal of Koya University2410-93552307-549X2025-06-0113110.14500/aro.12194Assessment of Leakage Radiation and Radiobiological Impacts in Gamma Knife RadiosurgeryBazhdar N. Mohammed0https://orcid.org/0000-0002-4637-5428Asaad H. Ismail1https://orcid.org/0000-0002-6308-5641Edrees M. Tahir2https://orcid.org/0009-0003-1970-696XDepartment of Physics, College of Education, Salahaddin University-Erbil, Erbil, Kurdistan Region – F.R. IraqDepartment of Physics, College of Education, Salahaddin University-Erbil, Erbil, Kurdistan Region – F.R. IraqDepartment of Medical Technical Radiology, Erbil Technical Health and Medical College, Erbil Polytechnic University, Erbil, Kurdistan Region – F.R. Iraq Gamma Knife radiosurgery is a non-invasive radiotherapy technique for brain lesions. However, radiation leakage from collimators and high-dose exposure may alter blood parameters, potentially increasing the risk of secondary cancers and other complications. The purpose of this study is to measure the leakage radiation produced during trigeminal neuralgia and meningiomas lesion treatments and impact on various radiosensitive organs. In addition, the radiobiological impact on patients’ blood parameters is investigated for both short-term and long-term treatment exposure. Scatter radiation was measured using dosimeters placed at various body regions. Blood samples were collected from 20 patients at three different times. Changes in parameters were statistically analyzed using one-way analysis of variance, to assess significant differences across the time points. The highest scatter radiation levels were recorded at the face and neck significantly exceeding other body regions about 110 μSv and 350 μSv, respectively. Statistical analysis revealed that long-term exposure (58.2 min at 80 Gy) in trigeminal neuralgia cases resulted in significantly greater blood parameter changes (p ≤ 0.05) compared to short-term exposure (19.4 min at 20 Gy) in meningiomas. These findings reveal dose-dependent blood changes and highlight the importance of radiation protection measures to enhance patient safety, particularly during high-dose treatments. https://aro.koyauniversity.org/index.php/aro/article/view/2194Gamma knife radiosurgeryLeakage radiationPatient SafetyRadiation doseRadiobiological impacts |
| spellingShingle | Bazhdar N. Mohammed Asaad H. Ismail Edrees M. Tahir Assessment of Leakage Radiation and Radiobiological Impacts in Gamma Knife Radiosurgery ARO-The Scientific Journal of Koya University Gamma knife radiosurgery Leakage radiation Patient Safety Radiation dose Radiobiological impacts |
| title | Assessment of Leakage Radiation and Radiobiological Impacts in Gamma Knife Radiosurgery |
| title_full | Assessment of Leakage Radiation and Radiobiological Impacts in Gamma Knife Radiosurgery |
| title_fullStr | Assessment of Leakage Radiation and Radiobiological Impacts in Gamma Knife Radiosurgery |
| title_full_unstemmed | Assessment of Leakage Radiation and Radiobiological Impacts in Gamma Knife Radiosurgery |
| title_short | Assessment of Leakage Radiation and Radiobiological Impacts in Gamma Knife Radiosurgery |
| title_sort | assessment of leakage radiation and radiobiological impacts in gamma knife radiosurgery |
| topic | Gamma knife radiosurgery Leakage radiation Patient Safety Radiation dose Radiobiological impacts |
| url | https://aro.koyauniversity.org/index.php/aro/article/view/2194 |
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