Trends in Life Expectancy of Cystic Fibrosis Patients in Moscow and their Connection with the Treatment Received: Retrospective Analysis for 1993–2013
Cystic fibrosis is multiple organ pathology that requires a complex treatment. Its standardization and pharmacoeconomic analysis are absolutely necessary. We performed a retrospective analysis of the trends in life expectancy of cystic fibrosis patients who lived inMoscow in 1993, 1998, 2003, 2008,...
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"Paediatrician" Publishers LLC
2015-09-01
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| author | N. Yu. Kashirskaya S. A. Krasovsky A. V. Chernyak V. D. Sherman A. Yu. Voronkova L. A. Shabalova V. S. Nikonova Yu. V. Gorinova O. I. Simonova E. L. Amelina E. I. Kondrat’eva N. I. Kapranov N. V. Petrova R. A. Zinchenko |
| author_facet | N. Yu. Kashirskaya S. A. Krasovsky A. V. Chernyak V. D. Sherman A. Yu. Voronkova L. A. Shabalova V. S. Nikonova Yu. V. Gorinova O. I. Simonova E. L. Amelina E. I. Kondrat’eva N. I. Kapranov N. V. Petrova R. A. Zinchenko |
| author_sort | N. Yu. Kashirskaya |
| collection | DOAJ |
| description | Cystic fibrosis is multiple organ pathology that requires a complex treatment. Its standardization and pharmacoeconomic analysis are absolutely necessary. We performed a retrospective analysis of the trends in life expectancy of cystic fibrosis patients who lived inMoscow in 1993, 1998, 2003, 2008, and 2013. It was found that the survival rate of these patients depended on the choice of drug therapy (pancreatic enzymes, dornase alfa, intravenous and inhaled antipseudomonal antibiotics), changes in diet, active dispensary observation at a specialized center for cystic fibrosis, and neonatal screening. We determined the cost of drug therapy per patient. From 1993 to 2013, the survival rate of patients who lived in Moscow increased by more than 20 years (from 16 to 39 years, respectively). The average cost of therapy increased more than 10 times (from USD 1.8 to 21.9 thousand, respectively). |
| format | Article |
| id | doaj-art-469ac005c5ab44a3b76219cbd0d47e2f |
| institution | Kabale University |
| issn | 1682-5527 1682-5535 |
| language | English |
| publishDate | 2015-09-01 |
| publisher | "Paediatrician" Publishers LLC |
| record_format | Article |
| series | Вопросы современной педиатрии |
| spelling | doaj-art-469ac005c5ab44a3b76219cbd0d47e2f2025-08-20T03:59:52Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352015-09-0114450350810.15690/vsp.v14.i4.13901084Trends in Life Expectancy of Cystic Fibrosis Patients in Moscow and their Connection with the Treatment Received: Retrospective Analysis for 1993–2013N. Yu. Kashirskaya0S. A. Krasovsky1A. V. Chernyak2V. D. Sherman3A. Yu. Voronkova4L. A. Shabalova5V. S. Nikonova6Yu. V. Gorinova7O. I. Simonova8E. L. Amelina9E. I. Kondrat’eva10N. I. Kapranov11N. V. Petrova12R. A. Zinchenko13Research Centre of Medical Genetics, Moscow, Russian FederationResearch Institute of Pulmonology, Moscow, Russian FederationResearch Institute of Pulmonology, Moscow, Russian FederationResearch Centre of Medical Genetics, Moscow, Russian FederationResearch Centre of Medical Genetics, Moscow, Russian FederationResearch Centre of Medical Genetics, Moscow, Russian FederationResearch Centre of Medical Genetics, Moscow, Russian FederationScientific Center of Children’s Health, Moscow, Russian FederationScientific Center of Children’s Health, Moscow, Russian FederationResearch Institute of Pulmonology, Moscow, Russian FederationResearch Centre of Medical Genetics, Moscow, Russian FederationResearch Centre of Medical Genetics, Moscow, Russian FederationResearch Centre of Medical Genetics, Moscow, Russian FederationResearch Centre of Medical Genetics, Moscow, Russian Federation Moscow State University of Medicine and Dentistry n.a. A.I. Evdokimov, Moscow, Russian FederationCystic fibrosis is multiple organ pathology that requires a complex treatment. Its standardization and pharmacoeconomic analysis are absolutely necessary. We performed a retrospective analysis of the trends in life expectancy of cystic fibrosis patients who lived inMoscow in 1993, 1998, 2003, 2008, and 2013. It was found that the survival rate of these patients depended on the choice of drug therapy (pancreatic enzymes, dornase alfa, intravenous and inhaled antipseudomonal antibiotics), changes in diet, active dispensary observation at a specialized center for cystic fibrosis, and neonatal screening. We determined the cost of drug therapy per patient. From 1993 to 2013, the survival rate of patients who lived in Moscow increased by more than 20 years (from 16 to 39 years, respectively). The average cost of therapy increased more than 10 times (from USD 1.8 to 21.9 thousand, respectively).https://vsp.spr-journal.ru/jour/article/view/1083cystic fibrosissurvival ratetreatmentcostdornase alfa. |
| spellingShingle | N. Yu. Kashirskaya S. A. Krasovsky A. V. Chernyak V. D. Sherman A. Yu. Voronkova L. A. Shabalova V. S. Nikonova Yu. V. Gorinova O. I. Simonova E. L. Amelina E. I. Kondrat’eva N. I. Kapranov N. V. Petrova R. A. Zinchenko Trends in Life Expectancy of Cystic Fibrosis Patients in Moscow and their Connection with the Treatment Received: Retrospective Analysis for 1993–2013 Вопросы современной педиатрии cystic fibrosis survival rate treatment cost dornase alfa. |
| title | Trends in Life Expectancy of Cystic Fibrosis Patients in Moscow and their Connection with the Treatment Received: Retrospective Analysis for 1993–2013 |
| title_full | Trends in Life Expectancy of Cystic Fibrosis Patients in Moscow and their Connection with the Treatment Received: Retrospective Analysis for 1993–2013 |
| title_fullStr | Trends in Life Expectancy of Cystic Fibrosis Patients in Moscow and their Connection with the Treatment Received: Retrospective Analysis for 1993–2013 |
| title_full_unstemmed | Trends in Life Expectancy of Cystic Fibrosis Patients in Moscow and their Connection with the Treatment Received: Retrospective Analysis for 1993–2013 |
| title_short | Trends in Life Expectancy of Cystic Fibrosis Patients in Moscow and their Connection with the Treatment Received: Retrospective Analysis for 1993–2013 |
| title_sort | trends in life expectancy of cystic fibrosis patients in moscow and their connection with the treatment received retrospective analysis for 1993 2013 |
| topic | cystic fibrosis survival rate treatment cost dornase alfa. |
| url | https://vsp.spr-journal.ru/jour/article/view/1083 |
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