Class-Specific Histone Deacetylase Inhibitors Promote 11-Beta Hydroxysteroid Dehydrogenase Type 2 Expression in JEG-3 Cells

Class-Specific Histone Deacetylase Inhibitors Promote 11-Beta Hydroxysteroid Dehydrogenase Type 2 Expression in JEG-3 Cells

Exposure to maternal cortisol plays a crucial role in fetal organogenesis. However, fetal overexposure to cortisol has been linked to a range of short- and long-term adverse outcomes. Normally, this is prevented by the expression of an enzyme in the placenta called 11-beta hydroxysteroid dehydrogena...

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Bibliographic Details
Main Authors: Katie L. Togher, Louise C. Kenny, Gerard W. O’Keeffe
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:International Journal of Cell Biology
Online Access:http://dx.doi.org/10.1155/2017/6169310
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