In-vitro effect of aflibercept and dexamethasone on the expression level of genes associated with epithelial-mesenchymal transition in retinal pigment epithelial cells

In-vitro effect of aflibercept and dexamethasone on the expression level of genes associated with epithelial-mesenchymal transition in retinal pigment epithelial cells

Purpose: Proliferative vitreoretinopathy (PVR) is the primary cause of surgical failure in retinal detachment repair, and the epithelial-mesenchymal transition (EMT) of retinal pigment epithelial (RPE) cells plays a crucial role in the pathophysiology of PVR. The purpose of this study was to investi...

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Main Authors: M. Hossein Nowroozzadeh, Hajar Farvardin, Seyed Ali Nabavizadeh, Fatemeh Sanie-Jahromi
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Heliyon
Subjects:
Aflibercept bevacizumab
Dexamethasone
Epithelial-mesenchymal transition
Proliferative vitreoretinopathy
Retinal pigment epithelium
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844025018523
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