Oxidized phospholipid and transcriptomic signatures of THC-related vaping associated lung injury

Oxidized phospholipid and transcriptomic signatures of THC-related vaping associated lung injury

Abstract E-cigarette/vaping-associated lung injury (EVALI) is strongly associated with vitamin E acetate and often occurs with concomitant tetrahydrocannabinol (THC) use. To uncover pathways associated with EVALI, we examined cytokines, transcriptomic signatures, and lipidomic profiles in bronchoalv...

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Main Authors: Tomeka L. Suber, Mohammadreza Tabary, William Bain, Tolani Olonisakin, Karina Lockwood, Zeyu Xiong, Yingze Zhang, Naina Kohli, Lauren Furguiele, Hernán Peñaloza, Bryan J. McVerry, Jason J. Rose, Faraaz Shah, Barbara Methé, Kelvin Li, Rama K. Mallampalli, Kong Chen, Li Fan, Alison Morris, Vladimir A. Tyurin, Svetlana N. Samovich, Hülya Bayir, Yulia Y. Tyurina, Valerian Kagan, Janet S. Lee
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Subjects:
Lipidomics
Vaping
Acute lung injury
Phospholipids
Online Access:https://doi.org/10.1038/s41598-024-79585-8
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