Multiple revision surgeries after total hip arthroplasty in a patient with osteopetrosis: a case report with 24 years of follow-up

Abstract Osteopetrosis, also recognized as marble bone disease, denotes a rare hereditary skeletal condition. It is distinguished by faulty osteoclast resorption, resulting in universally rigid and brittle bones. Secondary osteoarthritis often occurs in young and middle-aged patients with osteopetro...

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Main Authors: Wenkang Ling, Wei He, Leilei Chen
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Musculoskeletal Disorders
Subjects:
Online Access:https://doi.org/10.1186/s12891-025-08590-3
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author Wenkang Ling
Wei He
Leilei Chen
author_facet Wenkang Ling
Wei He
Leilei Chen
author_sort Wenkang Ling
collection DOAJ
description Abstract Osteopetrosis, also recognized as marble bone disease, denotes a rare hereditary skeletal condition. It is distinguished by faulty osteoclast resorption, resulting in universally rigid and brittle bones. Secondary osteoarthritis often occurs in young and middle-aged patients with osteopetrosis. They often have to have joint replacement surgery at a young age, which means they will likely face multiple revision surgeries. To draw attention to revision surgery, we present the case of an osteopetrosis patient who underwent multiple revision surgeries after total hip arthroplasty. Additionally, we suggest that this may be the first reported case of revision surgery utilizing a custom triflange acetabular component (CTAC) in a patient with osteopetrosis. These findings will offer valuable insights for selecting appropriate techniques and instruments for multiple revision surgeries of total hip arthroplasty in patients with osteopetrosis. Presently, total hip arthroplasty remains a valuable treatment option in osteopetrosis patients when executed with precision.
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spelling doaj-art-467dc05fef9649a18c7d121ccefccdda2025-08-20T02:55:28ZengBMCBMC Musculoskeletal Disorders1471-24742025-04-012611710.1186/s12891-025-08590-3Multiple revision surgeries after total hip arthroplasty in a patient with osteopetrosis: a case report with 24 years of follow-upWenkang Ling0Wei He1Leilei Chen2Third Clinical Medical College, Guangzhou University of Chinese MedicineDepartment of Orthopaedics, The Third Affiliated Hospital of Guangzhou University of Chinese MedicineDepartment of Orthopaedics, The Third Affiliated Hospital of Guangzhou University of Chinese MedicineAbstract Osteopetrosis, also recognized as marble bone disease, denotes a rare hereditary skeletal condition. It is distinguished by faulty osteoclast resorption, resulting in universally rigid and brittle bones. Secondary osteoarthritis often occurs in young and middle-aged patients with osteopetrosis. They often have to have joint replacement surgery at a young age, which means they will likely face multiple revision surgeries. To draw attention to revision surgery, we present the case of an osteopetrosis patient who underwent multiple revision surgeries after total hip arthroplasty. Additionally, we suggest that this may be the first reported case of revision surgery utilizing a custom triflange acetabular component (CTAC) in a patient with osteopetrosis. These findings will offer valuable insights for selecting appropriate techniques and instruments for multiple revision surgeries of total hip arthroplasty in patients with osteopetrosis. Presently, total hip arthroplasty remains a valuable treatment option in osteopetrosis patients when executed with precision.https://doi.org/10.1186/s12891-025-08590-3Total hip arthroplastyOsteopetrosisRevision surgeryCustom triflange acetabular component (CTAC)Case report
spellingShingle Wenkang Ling
Wei He
Leilei Chen
Multiple revision surgeries after total hip arthroplasty in a patient with osteopetrosis: a case report with 24 years of follow-up
BMC Musculoskeletal Disorders
Total hip arthroplasty
Osteopetrosis
Revision surgery
Custom triflange acetabular component (CTAC)
Case report
title Multiple revision surgeries after total hip arthroplasty in a patient with osteopetrosis: a case report with 24 years of follow-up
title_full Multiple revision surgeries after total hip arthroplasty in a patient with osteopetrosis: a case report with 24 years of follow-up
title_fullStr Multiple revision surgeries after total hip arthroplasty in a patient with osteopetrosis: a case report with 24 years of follow-up
title_full_unstemmed Multiple revision surgeries after total hip arthroplasty in a patient with osteopetrosis: a case report with 24 years of follow-up
title_short Multiple revision surgeries after total hip arthroplasty in a patient with osteopetrosis: a case report with 24 years of follow-up
title_sort multiple revision surgeries after total hip arthroplasty in a patient with osteopetrosis a case report with 24 years of follow up
topic Total hip arthroplasty
Osteopetrosis
Revision surgery
Custom triflange acetabular component (CTAC)
Case report
url https://doi.org/10.1186/s12891-025-08590-3
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AT leileichen multiplerevisionsurgeriesaftertotalhiparthroplastyinapatientwithosteopetrosisacasereportwith24yearsoffollowup