Micro-RNA Expression and Function in Lymphomas
The recent discovery of microRNAs (miRNAs) has introduced a new layer of complexity to the process of gene regulation. MiRNAs are essential for cellular function, and their dysregulation often results in disease. Study of miRNA expression and function in animal models and human lymphomas has improve...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2011-01-01
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| Series: | Advances in Hematology |
| Online Access: | http://dx.doi.org/10.1155/2011/347137 |
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| _version_ | 1832556330249879552 |
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| author | Sukhinder K. Sandhu Carlo M. Croce Ramiro Garzon |
| author_facet | Sukhinder K. Sandhu Carlo M. Croce Ramiro Garzon |
| author_sort | Sukhinder K. Sandhu |
| collection | DOAJ |
| description | The recent discovery of microRNAs (miRNAs) has introduced a new layer of complexity to the process of gene regulation. MiRNAs are essential for cellular function, and their dysregulation often results in disease. Study of miRNA expression and function in animal models and human lymphomas has improved our knowledge of the pathogenesis of this heterogeneous disease. In this paper, we attempt to describe the expression of miRNAs and their function in lymphomas and discuss potential miRNA-based therapies in the diagnosis and treatment of lymphomas. |
| format | Article |
| id | doaj-art-4677ba25a5da47db86c7acbd1579ac59 |
| institution | Kabale University |
| issn | 1687-9104 1687-9112 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advances in Hematology |
| spelling | doaj-art-4677ba25a5da47db86c7acbd1579ac592025-02-03T05:45:44ZengWileyAdvances in Hematology1687-91041687-91122011-01-01201110.1155/2011/347137347137Micro-RNA Expression and Function in LymphomasSukhinder K. Sandhu0Carlo M. Croce1Ramiro Garzon2Department of Molecular Virology, Immunology and Medical Genetics, Molecular and Cellular Developmental Biology Program, The Ohio State University Medical Center, Columbus, OH 43210, USADepartment of Molecular Virology, Immunology and Medical Genetics, Molecular and Cellular Developmental Biology Program, The Ohio State University Medical Center, Columbus, OH 43210, USADivision of Hematology, Department of Internal Medicine and Comprehensive Cancer Center, The Ohio State University Medical Center, Biomedical Research Tower, Room 1084, 460 West 12th Avenue, Columbus, OH 43210, USAThe recent discovery of microRNAs (miRNAs) has introduced a new layer of complexity to the process of gene regulation. MiRNAs are essential for cellular function, and their dysregulation often results in disease. Study of miRNA expression and function in animal models and human lymphomas has improved our knowledge of the pathogenesis of this heterogeneous disease. In this paper, we attempt to describe the expression of miRNAs and their function in lymphomas and discuss potential miRNA-based therapies in the diagnosis and treatment of lymphomas.http://dx.doi.org/10.1155/2011/347137 |
| spellingShingle | Sukhinder K. Sandhu Carlo M. Croce Ramiro Garzon Micro-RNA Expression and Function in Lymphomas Advances in Hematology |
| title | Micro-RNA Expression and Function in Lymphomas |
| title_full | Micro-RNA Expression and Function in Lymphomas |
| title_fullStr | Micro-RNA Expression and Function in Lymphomas |
| title_full_unstemmed | Micro-RNA Expression and Function in Lymphomas |
| title_short | Micro-RNA Expression and Function in Lymphomas |
| title_sort | micro rna expression and function in lymphomas |
| url | http://dx.doi.org/10.1155/2011/347137 |
| work_keys_str_mv | AT sukhinderksandhu micrornaexpressionandfunctioninlymphomas AT carlomcroce micrornaexpressionandfunctioninlymphomas AT ramirogarzon micrornaexpressionandfunctioninlymphomas |