Protocol for the RoboSling Trial: A Randomised Study Assessing Urinary Continence Following Robotic Radical Prostatectomy with or without an Intraoperative Retropubic Vascularised Fascial Sling (RoboSling)

<b>Objectives:</b> To determine if early (three months) and late (one year) post-operative continence is improved by performing a novel retropubic vascularised fascial sling (RoboSling) procedure concurrently with robot-assisted radical prostatectomy in men undergoing treatment for local...

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Main Authors: Amandeep Virk, Patrick-Julien Treacy, Wenjie Zhong, Stuart Robert Jackson, Nariman Ahmadi, Nicola Nadia Jeffery, Lewis Chan, Paul Sved, Arthur Vasilaras, Ruban Thanigasalam, Scott Leslie
Format: Article
Language:English
Published: MDPI AG 2024-04-01
Series:Société Internationale d’Urologie Journal
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Online Access:https://www.mdpi.com/2563-6499/5/2/24
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author Amandeep Virk
Patrick-Julien Treacy
Wenjie Zhong
Stuart Robert Jackson
Nariman Ahmadi
Nicola Nadia Jeffery
Lewis Chan
Paul Sved
Arthur Vasilaras
Ruban Thanigasalam
Scott Leslie
author_facet Amandeep Virk
Patrick-Julien Treacy
Wenjie Zhong
Stuart Robert Jackson
Nariman Ahmadi
Nicola Nadia Jeffery
Lewis Chan
Paul Sved
Arthur Vasilaras
Ruban Thanigasalam
Scott Leslie
author_sort Amandeep Virk
collection DOAJ
description <b>Objectives:</b> To determine if early (three months) and late (one year) post-operative continence is improved by performing a novel retropubic vascularised fascial sling (RoboSling) procedure concurrently with robot-assisted radical prostatectomy in men undergoing treatment for localised prostate cancer. To additionally assess surgical outcomes, quality of life and health economic outcomes in patients undergoing the novel RoboSling technique. <b>Methods:</b> This study aims to recruit 120 consecutive patients with clinically localised prostate cancer who have chosen to undergo robot-assisted radical prostatectomy in the Sydney Local Health District, Australia. A prospective assessment of early and late post-operative continence following robot-assisted radical prostatectomy with and without a RoboSling procedure will be performed in a two-group, 1:1, parallel, randomized controlled trial. Four surgeons will take part in the study, all of whom are beyond their learning curve. Patients will be blinded as to whether the RoboSling procedure is performed for them, as will be the research officers collecting the post-operative data on urinary function. Trial Registration: ACTRN12618002058257. <b>Results:</b> The trial is currently underway. <b>Conclusions:</b> The RoboSling technique is unique in that the sling is vascularised and has a broad surface area compared to previously described slings in the literature. If a clinically significant improvement in post-operative continence is established with the RoboSling, then, we can in turn expect improvements in quality of life for men undergoing this technique with radical prostatectomy.
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spelling doaj-art-465da5d1a51e4551bd9f63c2b2c10eea2025-08-20T01:56:42ZengMDPI AGSociété Internationale d’Urologie Journal2563-64992024-04-015214815910.3390/siuj5020024Protocol for the RoboSling Trial: A Randomised Study Assessing Urinary Continence Following Robotic Radical Prostatectomy with or without an Intraoperative Retropubic Vascularised Fascial Sling (RoboSling)Amandeep Virk0Patrick-Julien Treacy1Wenjie Zhong2Stuart Robert Jackson3Nariman Ahmadi4Nicola Nadia Jeffery5Lewis Chan6Paul Sved7Arthur Vasilaras8Ruban Thanigasalam9Scott Leslie10Department of Uro-Oncology, Chris O’Brien Lifehouse, Camperdown, NSW 2050, AustraliaThe Institute of Academic Surgery at Royal Prince Alfred Hospital, Camperdown, NSW 2050, AustraliaFaculty of Medicine and Health, The University of Sydney, Camperdown, NSW 2050, AustraliaDepartment of Urology, Royal Prince Alfred Hospital, Camperdown, NSW 2050, AustraliaDepartment of Uro-Oncology, Chris O’Brien Lifehouse, Camperdown, NSW 2050, AustraliaDepartment of Urology, Royal Prince Alfred Hospital, Camperdown, NSW 2050, AustraliaFaculty of Medicine and Health, The University of Sydney, Camperdown, NSW 2050, AustraliaDepartment of Urology, Royal Prince Alfred Hospital, Camperdown, NSW 2050, AustraliaDepartment of Urology, Royal Prince Alfred Hospital, Camperdown, NSW 2050, AustraliaDepartment of Uro-Oncology, Chris O’Brien Lifehouse, Camperdown, NSW 2050, AustraliaDepartment of Uro-Oncology, Chris O’Brien Lifehouse, Camperdown, NSW 2050, Australia<b>Objectives:</b> To determine if early (three months) and late (one year) post-operative continence is improved by performing a novel retropubic vascularised fascial sling (RoboSling) procedure concurrently with robot-assisted radical prostatectomy in men undergoing treatment for localised prostate cancer. To additionally assess surgical outcomes, quality of life and health economic outcomes in patients undergoing the novel RoboSling technique. <b>Methods:</b> This study aims to recruit 120 consecutive patients with clinically localised prostate cancer who have chosen to undergo robot-assisted radical prostatectomy in the Sydney Local Health District, Australia. A prospective assessment of early and late post-operative continence following robot-assisted radical prostatectomy with and without a RoboSling procedure will be performed in a two-group, 1:1, parallel, randomized controlled trial. Four surgeons will take part in the study, all of whom are beyond their learning curve. Patients will be blinded as to whether the RoboSling procedure is performed for them, as will be the research officers collecting the post-operative data on urinary function. Trial Registration: ACTRN12618002058257. <b>Results:</b> The trial is currently underway. <b>Conclusions:</b> The RoboSling technique is unique in that the sling is vascularised and has a broad surface area compared to previously described slings in the literature. If a clinically significant improvement in post-operative continence is established with the RoboSling, then, we can in turn expect improvements in quality of life for men undergoing this technique with radical prostatectomy.https://www.mdpi.com/2563-6499/5/2/24incontinenceintraoperative slingprostate cancerprostatectomyrobotic surgery
spellingShingle Amandeep Virk
Patrick-Julien Treacy
Wenjie Zhong
Stuart Robert Jackson
Nariman Ahmadi
Nicola Nadia Jeffery
Lewis Chan
Paul Sved
Arthur Vasilaras
Ruban Thanigasalam
Scott Leslie
Protocol for the RoboSling Trial: A Randomised Study Assessing Urinary Continence Following Robotic Radical Prostatectomy with or without an Intraoperative Retropubic Vascularised Fascial Sling (RoboSling)
Société Internationale d’Urologie Journal
incontinence
intraoperative sling
prostate cancer
prostatectomy
robotic surgery
title Protocol for the RoboSling Trial: A Randomised Study Assessing Urinary Continence Following Robotic Radical Prostatectomy with or without an Intraoperative Retropubic Vascularised Fascial Sling (RoboSling)
title_full Protocol for the RoboSling Trial: A Randomised Study Assessing Urinary Continence Following Robotic Radical Prostatectomy with or without an Intraoperative Retropubic Vascularised Fascial Sling (RoboSling)
title_fullStr Protocol for the RoboSling Trial: A Randomised Study Assessing Urinary Continence Following Robotic Radical Prostatectomy with or without an Intraoperative Retropubic Vascularised Fascial Sling (RoboSling)
title_full_unstemmed Protocol for the RoboSling Trial: A Randomised Study Assessing Urinary Continence Following Robotic Radical Prostatectomy with or without an Intraoperative Retropubic Vascularised Fascial Sling (RoboSling)
title_short Protocol for the RoboSling Trial: A Randomised Study Assessing Urinary Continence Following Robotic Radical Prostatectomy with or without an Intraoperative Retropubic Vascularised Fascial Sling (RoboSling)
title_sort protocol for the robosling trial a randomised study assessing urinary continence following robotic radical prostatectomy with or without an intraoperative retropubic vascularised fascial sling robosling
topic incontinence
intraoperative sling
prostate cancer
prostatectomy
robotic surgery
url https://www.mdpi.com/2563-6499/5/2/24
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