What can be observed in intervertebral cartilage endplate with aging? An animal model study of excessive axial mechanical loading

IntroductionThe cartilage endplate (CEP) plays a crucial role as both a mechanical barrier and nutrient channel for the intervertebral disc, but it is vulnerable to excessive axial loading. We modified the Ilizarov external fixator and applied it to the CEP of the rat tail to impose diurnal, control...

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Bibliographic Details
Main Authors: Zhouyang Hu, Fan He, Xinhua Li, Bei Jiang, Shuaifeng Yan, Jun Tan, Lijun Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2024.1429208/full
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