Validity of the International HIV Dementia Scale in Brazil

HIV-associated neurocognitive disorders (HAND) remain prevalent in highly active antiretroviral therapy (HAART) era. Tests to detect HAND are needed for early diagnosis and treatment. Validity of International HIV Dementia Scale (IHDS) has been determined in different countries. The aims of this stu...

Full description

Saved in:
Bibliographic Details
Main Authors: Roiza Almeida Rodrigues, Raquel Lisboa Oliveira, Beatriz Grinsztejn, Marcus Tulius T. Silva
Format: Article
Language:English
Published: Thieme Revinter Publicações 2013-06-01
Series:Arquivos de Neuro-Psiquiatria
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2013000600376&lng=en&tlng=en
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850182065249583104
author Roiza Almeida Rodrigues
Raquel Lisboa Oliveira
Beatriz Grinsztejn
Marcus Tulius T. Silva
author_facet Roiza Almeida Rodrigues
Raquel Lisboa Oliveira
Beatriz Grinsztejn
Marcus Tulius T. Silva
author_sort Roiza Almeida Rodrigues
collection DOAJ
description HIV-associated neurocognitive disorders (HAND) remain prevalent in highly active antiretroviral therapy (HAART) era. Tests to detect HAND are needed for early diagnosis and treatment. Validity of International HIV Dementia Scale (IHDS) has been determined in different countries. The aims of this study were validate IHDS in a Brazilian cohort of HIV-patients and verify if IHDS can be reliably administered by a non-clinician health professional. One hundred and eighty-seven (187) patients were submitted to a full neuropsychological assessment. IHDS was administered twice to each patient (by a non-clinician and by a neurologist). HAND was diagnosed in 98 individuals (68 on HAART). IHDS had sensitivity of 55% and specificity of 80%. IHDS had fair agreement with neuropsychological tests (k 0.355) and moderate-to-strong agreement between different evaluators (interclass correlation coefficient (ICC) 0.684). HAND is prevalent nowadays. IHDS is quick and easy to administer, but has marginal sensitivity for the detection of HIV cognitive impairment other than dementia.
format Article
id doaj-art-464ab2548cab4a348d3caa70cdff1724
institution OA Journals
issn 1678-4227
language English
publishDate 2013-06-01
publisher Thieme Revinter Publicações
record_format Article
series Arquivos de Neuro-Psiquiatria
spelling doaj-art-464ab2548cab4a348d3caa70cdff17242025-08-20T02:17:45ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42272013-06-0171637637910.1590/0004-282X20130042S0004-282X2013000600376Validity of the International HIV Dementia Scale in BrazilRoiza Almeida RodriguesRaquel Lisboa OliveiraBeatriz GrinsztejnMarcus Tulius T. SilvaHIV-associated neurocognitive disorders (HAND) remain prevalent in highly active antiretroviral therapy (HAART) era. Tests to detect HAND are needed for early diagnosis and treatment. Validity of International HIV Dementia Scale (IHDS) has been determined in different countries. The aims of this study were validate IHDS in a Brazilian cohort of HIV-patients and verify if IHDS can be reliably administered by a non-clinician health professional. One hundred and eighty-seven (187) patients were submitted to a full neuropsychological assessment. IHDS was administered twice to each patient (by a non-clinician and by a neurologist). HAND was diagnosed in 98 individuals (68 on HAART). IHDS had sensitivity of 55% and specificity of 80%. IHDS had fair agreement with neuropsychological tests (k 0.355) and moderate-to-strong agreement between different evaluators (interclass correlation coefficient (ICC) 0.684). HAND is prevalent nowadays. IHDS is quick and easy to administer, but has marginal sensitivity for the detection of HIV cognitive impairment other than dementia.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2013000600376&lng=en&tlng=enAcquired Immunodeficiency SyndromeHIVdementiaSindrome de Imunodeficiencia AdquiridaHIVdemencia
spellingShingle Roiza Almeida Rodrigues
Raquel Lisboa Oliveira
Beatriz Grinsztejn
Marcus Tulius T. Silva
Validity of the International HIV Dementia Scale in Brazil
Arquivos de Neuro-Psiquiatria
Acquired Immunodeficiency Syndrome
HIV
dementia
Sindrome de Imunodeficiencia Adquirida
HIV
demencia
title Validity of the International HIV Dementia Scale in Brazil
title_full Validity of the International HIV Dementia Scale in Brazil
title_fullStr Validity of the International HIV Dementia Scale in Brazil
title_full_unstemmed Validity of the International HIV Dementia Scale in Brazil
title_short Validity of the International HIV Dementia Scale in Brazil
title_sort validity of the international hiv dementia scale in brazil
topic Acquired Immunodeficiency Syndrome
HIV
dementia
Sindrome de Imunodeficiencia Adquirida
HIV
demencia
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2013000600376&lng=en&tlng=en
work_keys_str_mv AT roizaalmeidarodrigues validityoftheinternationalhivdementiascaleinbrazil
AT raquellisboaoliveira validityoftheinternationalhivdementiascaleinbrazil
AT beatrizgrinsztejn validityoftheinternationalhivdementiascaleinbrazil
AT marcustuliustsilva validityoftheinternationalhivdementiascaleinbrazil