Inhibition of Synovial Macrophage Pyroptosis Alleviates Synovitis and Fibrosis in Knee Osteoarthritis
Increasing evidence has shown that macrophage pyroptosis in different tissues participates in chronic aseptic inflammation and is related to tissue fibrosis. Our last studies also revealed the vital role of synovial fibroblast pyroptosis in the onset and development of knee osteoarthritis (KOA). In...
Saved in:
Main Authors: | Li Zhang, Runlin Xing, Zhengquan Huang, Nongshan Zhang, Xiaochen Li, Peimin Wang |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2019-01-01
|
Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/2019/2165918 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Targeting NLRP3 Inflammasome Alleviates Synovitis by Reducing Pyroptosis in Rats with Experimental Temporomandibular Joint Osteoarthritis
by: Yinzi Xin, et al.
Published: (2022-01-01) -
4-Octyl itaconate inhibits synovitis in the mouse model of post-traumatic osteoarthritis and alleviates pain
by: Yu-Zhen Tang, et al.
Published: (2025-01-01) -
Synovitis scoring in hand osteoarthritis with ultrasonography: the performance of the Global OMERACT/EULAR Ultrasound Synovitis Score (GLOESS) is comparable to synovial thickening alone
by: Féline P B Kroon, et al.
Published: (2024-12-01) -
Effects of Tongluo Zhitong formula on synovial fibroblast proliferation in human knee osteoarthritis
by: Li-Li Yang, et al.
Published: (2025-01-01) -
Suberosin attenuates rheumatoid arthritis by repolarizing macrophages and inhibiting synovitis via the JAK/STAT signaling pathway
by: Huan Liu, et al.
Published: (2025-01-01)