Synthesis methods impact silver nanoparticle properties and phenolic compound production in grapevine cell cultures

Abstract Silver nanoparticles (AgNPs) are one of nanoparticles with promising applications in various fields due to their unique characteristics. This study was carried out to determine the effects of AgNPs obtained by different green syntheses procedures on their characteristic properties and the a...

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Main Authors: Nilgün GöktürkBaydar, Zehra Babalik, Tunahan Demirci, Alper Cessur
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-85545-7
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author Nilgün GöktürkBaydar
Zehra Babalik
Tunahan Demirci
Alper Cessur
author_facet Nilgün GöktürkBaydar
Zehra Babalik
Tunahan Demirci
Alper Cessur
author_sort Nilgün GöktürkBaydar
collection DOAJ
description Abstract Silver nanoparticles (AgNPs) are one of nanoparticles with promising applications in various fields due to their unique characteristics. This study was carried out to determine the effects of AgNPs obtained by different green syntheses procedures on their characteristic properties and the accumulation of phenolic compounds in cell suspension cultures of Kalecik Karası grape cultivar. AgNPs were obtained by 24 different green synthesis methods including modifications in extraction method, reaction pH and conditions. When the results of the analyses conducted to determine the structural properties of AgNPs are evaluated, it was observed that more spherical and smaller nanoparticles were synthesized under alkaline conditions. The smallest NP size was detected as 8.9 nm in NP11, while the largest NP size (59.6 nm) was found in NP19. AgNPs obtained at room conditions for 4 h and pH 7 significantly increased the total phenolic, trans-resveratrol, catechin and epicatechin contents, while water or methanol extracts used in the synthesis had no significant effect. As a result of the study, it was determined that not only the characteristic properties of AgNPs but also their effectiveness on the secondary metabolite production varied significantly depending on the extraction method, pH and conditions of the reaction solution during synthesis.
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issn 2045-2322
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spelling doaj-art-4644a560bca24c1a959dcd8ba459bafb2025-08-20T02:59:20ZengNature PortfolioScientific Reports2045-23222025-03-0115112110.1038/s41598-025-85545-7Synthesis methods impact silver nanoparticle properties and phenolic compound production in grapevine cell culturesNilgün GöktürkBaydar0Zehra Babalik1Tunahan Demirci2Alper Cessur3Department of Agricultural Biotechnology, Faculty of Agriculture, Isparta University of Applied SciencesDepartment of Plant and Animal Production, Atabey Vocational School, Isparta University of Applied SciencesDepartment of Pharmaceutical Biotechnology, Faculty of Pharmacy, Suleyman Demirel UniversityDepartment of Agricultural Biotechnology, Faculty of Agriculture, Isparta University of Applied SciencesAbstract Silver nanoparticles (AgNPs) are one of nanoparticles with promising applications in various fields due to their unique characteristics. This study was carried out to determine the effects of AgNPs obtained by different green syntheses procedures on their characteristic properties and the accumulation of phenolic compounds in cell suspension cultures of Kalecik Karası grape cultivar. AgNPs were obtained by 24 different green synthesis methods including modifications in extraction method, reaction pH and conditions. When the results of the analyses conducted to determine the structural properties of AgNPs are evaluated, it was observed that more spherical and smaller nanoparticles were synthesized under alkaline conditions. The smallest NP size was detected as 8.9 nm in NP11, while the largest NP size (59.6 nm) was found in NP19. AgNPs obtained at room conditions for 4 h and pH 7 significantly increased the total phenolic, trans-resveratrol, catechin and epicatechin contents, while water or methanol extracts used in the synthesis had no significant effect. As a result of the study, it was determined that not only the characteristic properties of AgNPs but also their effectiveness on the secondary metabolite production varied significantly depending on the extraction method, pH and conditions of the reaction solution during synthesis.https://doi.org/10.1038/s41598-025-85545-7Silver nanoparticlesGreen synthesisKalecik KarasıCell suspension culturesPhenolic compounds
spellingShingle Nilgün GöktürkBaydar
Zehra Babalik
Tunahan Demirci
Alper Cessur
Synthesis methods impact silver nanoparticle properties and phenolic compound production in grapevine cell cultures
Scientific Reports
Silver nanoparticles
Green synthesis
Kalecik Karası
Cell suspension cultures
Phenolic compounds
title Synthesis methods impact silver nanoparticle properties and phenolic compound production in grapevine cell cultures
title_full Synthesis methods impact silver nanoparticle properties and phenolic compound production in grapevine cell cultures
title_fullStr Synthesis methods impact silver nanoparticle properties and phenolic compound production in grapevine cell cultures
title_full_unstemmed Synthesis methods impact silver nanoparticle properties and phenolic compound production in grapevine cell cultures
title_short Synthesis methods impact silver nanoparticle properties and phenolic compound production in grapevine cell cultures
title_sort synthesis methods impact silver nanoparticle properties and phenolic compound production in grapevine cell cultures
topic Silver nanoparticles
Green synthesis
Kalecik Karası
Cell suspension cultures
Phenolic compounds
url https://doi.org/10.1038/s41598-025-85545-7
work_keys_str_mv AT nilgungokturkbaydar synthesismethodsimpactsilvernanoparticlepropertiesandphenoliccompoundproductioningrapevinecellcultures
AT zehrababalik synthesismethodsimpactsilvernanoparticlepropertiesandphenoliccompoundproductioningrapevinecellcultures
AT tunahandemirci synthesismethodsimpactsilvernanoparticlepropertiesandphenoliccompoundproductioningrapevinecellcultures
AT alpercessur synthesismethodsimpactsilvernanoparticlepropertiesandphenoliccompoundproductioningrapevinecellcultures