Synchronization of autonomic control loops of blood circulation in patients with COVID-19

This study aims to investigate the strength of synchronization between the autonomic control loops of the cardiovascular system (CVS) in patients with COronaVIrus Disease 2019 (COVID-19). Methods — We calculated the total percent of phase synchronization index (S index) between the loops of autonom...

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Main Authors: Viktoriia V. Skazkina, Natalia S. Krasikova, Ekaterina I. Borovkova, Yurii M. Ishbulatov, Alexander Yu. Gorshkov, Andrei I. Korolev, Valida A. Dadaeva, Andrei A. Fedorovich, Alexander V. Kuligin, Oxana M. Drapkina, Anatoly S. Karavaev, Anton R. Kiselev
Format: Article
Language:English
Published: Limited liability company «Science and Innovations» (Saratov) 2021-09-01
Series:Russian Open Medical Journal
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Online Access:https://romj.org/node/397
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author Viktoriia V. Skazkina
Natalia S. Krasikova
Ekaterina I. Borovkova
Yurii M. Ishbulatov
Alexander Yu. Gorshkov
Andrei I. Korolev
Valida A. Dadaeva
Andrei A. Fedorovich
Alexander V. Kuligin
Oxana M. Drapkina
Anatoly S. Karavaev
Anton R. Kiselev
author_facet Viktoriia V. Skazkina
Natalia S. Krasikova
Ekaterina I. Borovkova
Yurii M. Ishbulatov
Alexander Yu. Gorshkov
Andrei I. Korolev
Valida A. Dadaeva
Andrei A. Fedorovich
Alexander V. Kuligin
Oxana M. Drapkina
Anatoly S. Karavaev
Anton R. Kiselev
author_sort Viktoriia V. Skazkina
collection DOAJ
description This study aims to investigate the strength of synchronization between the autonomic control loops of the cardiovascular system (CVS) in patients with COronaVIrus Disease 2019 (COVID-19). Methods — We calculated the total percent of phase synchronization index (S index) between the loops of autonomic control of heart rate and vascular tone in two sample groups: healthy individuals and COVID-19 patients. Results — The group-average value of the S index in COVID-19 patients is lower comparing to healthy individuals, the Mann-Whitney U-test confirmed that the differences are statistically significant. Conclusion — Obtained results suggest that the decreased value of the S index reflects the presence of a viral disease, and the S index is a promising basis for non-invasive screening diagnostics of viral diseases, particularly of COVID-19.
format Article
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institution DOAJ
issn 2304-3415
language English
publishDate 2021-09-01
publisher Limited liability company «Science and Innovations» (Saratov)
record_format Article
series Russian Open Medical Journal
spelling doaj-art-4640e423620848098f951d5d6043ef762025-08-20T03:19:17ZengLimited liability company «Science and Innovations» (Saratov)Russian Open Medical Journal2304-34152021-09-01103e030710.15275/rusomj.2021.0307Synchronization of autonomic control loops of blood circulation in patients with COVID-19Viktoriia V. SkazkinaNatalia S. KrasikovaEkaterina I. BorovkovaYurii M. IshbulatovAlexander Yu. GorshkovAndrei I. KorolevValida A. DadaevaAndrei A. FedorovichAlexander V. KuliginOxana M. DrapkinaAnatoly S. KaravaevAnton R. KiselevThis study aims to investigate the strength of synchronization between the autonomic control loops of the cardiovascular system (CVS) in patients with COronaVIrus Disease 2019 (COVID-19). Methods — We calculated the total percent of phase synchronization index (S index) between the loops of autonomic control of heart rate and vascular tone in two sample groups: healthy individuals and COVID-19 patients. Results — The group-average value of the S index in COVID-19 patients is lower comparing to healthy individuals, the Mann-Whitney U-test confirmed that the differences are statistically significant. Conclusion — Obtained results suggest that the decreased value of the S index reflects the presence of a viral disease, and the S index is a promising basis for non-invasive screening diagnostics of viral diseases, particularly of COVID-19.https://romj.org/node/397low-frequency oscillationsheart rate variabilityphotoplethysmogramphase synchronizationautonomic controlcovid-19
spellingShingle Viktoriia V. Skazkina
Natalia S. Krasikova
Ekaterina I. Borovkova
Yurii M. Ishbulatov
Alexander Yu. Gorshkov
Andrei I. Korolev
Valida A. Dadaeva
Andrei A. Fedorovich
Alexander V. Kuligin
Oxana M. Drapkina
Anatoly S. Karavaev
Anton R. Kiselev
Synchronization of autonomic control loops of blood circulation in patients with COVID-19
Russian Open Medical Journal
low-frequency oscillations
heart rate variability
photoplethysmogram
phase synchronization
autonomic control
covid-19
title Synchronization of autonomic control loops of blood circulation in patients with COVID-19
title_full Synchronization of autonomic control loops of blood circulation in patients with COVID-19
title_fullStr Synchronization of autonomic control loops of blood circulation in patients with COVID-19
title_full_unstemmed Synchronization of autonomic control loops of blood circulation in patients with COVID-19
title_short Synchronization of autonomic control loops of blood circulation in patients with COVID-19
title_sort synchronization of autonomic control loops of blood circulation in patients with covid 19
topic low-frequency oscillations
heart rate variability
photoplethysmogram
phase synchronization
autonomic control
covid-19
url https://romj.org/node/397
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