Fibrodysplasia ossificans progressiva - can we diagnose it right at the outset?

Fibrodysplasia ossificans progressiva (FOP) is a rare autosomal dominant disorder with no definitive treatment options available yet, except for physiotherapy and bisphosphonates. Due to its initial presentation with multiple lumps in the body, it is often misdiagnosed as a benign tumour most commo...

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Main Authors: Amit Sharma, Dhruv Maini, Gaurang Agarwal, Parul Sharma, Lalit Maini
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 2019-12-01
Series:The Turkish Journal of Pediatrics
Subjects:
Online Access:https://turkjpediatr.org/article/view/799
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author Amit Sharma
Dhruv Maini
Gaurang Agarwal
Parul Sharma
Lalit Maini
author_facet Amit Sharma
Dhruv Maini
Gaurang Agarwal
Parul Sharma
Lalit Maini
author_sort Amit Sharma
collection DOAJ
description Fibrodysplasia ossificans progressiva (FOP) is a rare autosomal dominant disorder with no definitive treatment options available yet, except for physiotherapy and bisphosphonates. Due to its initial presentation with multiple lumps in the body, it is often misdiagnosed as a benign tumour most commonly being an osteochondroma or Olliers syndrome. Delay in diagnosis not only delays the management but can also expose the patient to unnecessary interventions. Moreover, earlier diagnosis can also make the patient aware of the precautions to be taken. So our remark is `can we diagnose this disease right at the outset`? We present a case of a 10 year old boy, who had all the classical features of FOP yet was misdiagnosed. Therefore, classical hallmark features of this disease are highlighted in this case report which can be picked up easily by any clinician to reach to a definitive diagnosis as early as possible avoiding unnecessary iatrogenic insult.
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id doaj-art-463ec4b477b64f10b27ac35479738b2f
institution DOAJ
issn 0041-4301
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language English
publishDate 2019-12-01
publisher Hacettepe University Institute of Child Health
record_format Article
series The Turkish Journal of Pediatrics
spelling doaj-art-463ec4b477b64f10b27ac35479738b2f2025-08-20T02:55:38ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212019-12-0161610.24953/turkjped.2019.06.021Fibrodysplasia ossificans progressiva - can we diagnose it right at the outset?Amit Sharma0Dhruv Maini1Gaurang Agarwal2Parul Sharma3Lalit Maini4Department of Orthopaedics, Maulana Azad Medical College, Delhi.Gajra Raja Medical College, Gwalior, India.Department of Orthopaedics, Maulana Azad Medical College, Delhi.Department of Physiotherapy, Jamia Milia Islamia, Delhi.Department of Orthopaedics, Maulana Azad Medical College, Delhi. Fibrodysplasia ossificans progressiva (FOP) is a rare autosomal dominant disorder with no definitive treatment options available yet, except for physiotherapy and bisphosphonates. Due to its initial presentation with multiple lumps in the body, it is often misdiagnosed as a benign tumour most commonly being an osteochondroma or Olliers syndrome. Delay in diagnosis not only delays the management but can also expose the patient to unnecessary interventions. Moreover, earlier diagnosis can also make the patient aware of the precautions to be taken. So our remark is `can we diagnose this disease right at the outset`? We present a case of a 10 year old boy, who had all the classical features of FOP yet was misdiagnosed. Therefore, classical hallmark features of this disease are highlighted in this case report which can be picked up easily by any clinician to reach to a definitive diagnosis as early as possible avoiding unnecessary iatrogenic insult. https://turkjpediatr.org/article/view/799bisphosphonatesfibrodysplasia ossificans progressivaheterotopicossificationosteochondroma
spellingShingle Amit Sharma
Dhruv Maini
Gaurang Agarwal
Parul Sharma
Lalit Maini
Fibrodysplasia ossificans progressiva - can we diagnose it right at the outset?
The Turkish Journal of Pediatrics
bisphosphonates
fibrodysplasia ossificans progressiva
heterotopic
ossification
osteochondroma
title Fibrodysplasia ossificans progressiva - can we diagnose it right at the outset?
title_full Fibrodysplasia ossificans progressiva - can we diagnose it right at the outset?
title_fullStr Fibrodysplasia ossificans progressiva - can we diagnose it right at the outset?
title_full_unstemmed Fibrodysplasia ossificans progressiva - can we diagnose it right at the outset?
title_short Fibrodysplasia ossificans progressiva - can we diagnose it right at the outset?
title_sort fibrodysplasia ossificans progressiva can we diagnose it right at the outset
topic bisphosphonates
fibrodysplasia ossificans progressiva
heterotopic
ossification
osteochondroma
url https://turkjpediatr.org/article/view/799
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AT parulsharma fibrodysplasiaossificansprogressivacanwediagnoseitrightattheoutset
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