Mixed germ cell tumor on an ectopic ovary with in a 9-year-old girl: A rare and complex case

Malignant ovarian germ cell tumors are rare in the pediatric population, particularly in children under ten years of age. We report a unique case of a mixed germ cell tumor, comprising dysgerminoma, mature and immature teratomas, and yolk sac tumor, located on an ectopic ovary, which was discovered...

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Main Authors: Chaimae ABOURAK, Siham Oukassem, Wadie Zouita, Imade Bougrine, Jaouad Bouljrouf, Lina Belkouchi, Nazik Allali, Mounir Kisra, Latifa Chat, Siham El Haddad
Format: Article
Language:English
Published: Elsevier 2025-11-01
Series:Radiology Case Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S1930043325007150
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Summary:Malignant ovarian germ cell tumors are rare in the pediatric population, particularly in children under ten years of age. We report a unique case of a mixed germ cell tumor, comprising dysgerminoma, mature and immature teratomas, and yolk sac tumor, located on an ectopic ovary, which was discovered following adnexal torsion in a 9-year-old girl with a family history of gynecological cancers. Mixed germ cell tumors present significant diagnostic challenges due to their heterogeneous histological composition and complex biological behavior. The patient's family history of gynecological cancers raises the possibility of an underlying genetic predisposition. This case underscores the importance of a comprehensive approach to pediatric pelvic masses, particularly in patients with a significant family history of cancer. Long-term follow-up is crucial for the early detection of recurrence in complex germ cell tumors.
ISSN:1930-0433