Assessment of Long-Term Pulmonary Function and Quality of Life in Patients with Chronic Obstructive Pulmonary Disease (COPD)

Background: Chronic obstructive pulmonary disease (COPD) is a prevalent respiratory condition portrayed by persistent airflow limitation and correlated symptoms. Despite advances in treatment, COPD remains a significant global health burden, necessitating ongoing research to understand its long-stan...

Full description

Saved in:
Bibliographic Details
Main Authors: Sanjay D. Gabhale, Mahavir Satishchand Bagrecha, Mitali Dash, Zeeshan Sheikh, S. Bhuvaneshwari, Rangraze Imran, Tharini Satheesh
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-08-01
Series:Journal of Pharmacy and Bioallied Sciences
Subjects:
Online Access:https://journals.lww.com/10.4103/jpbs.jpbs_252_24
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850281804622200832
author Sanjay D. Gabhale
Mahavir Satishchand Bagrecha
Mitali Dash
Zeeshan Sheikh
S. Bhuvaneshwari
Rangraze Imran
Tharini Satheesh
author_facet Sanjay D. Gabhale
Mahavir Satishchand Bagrecha
Mitali Dash
Zeeshan Sheikh
S. Bhuvaneshwari
Rangraze Imran
Tharini Satheesh
author_sort Sanjay D. Gabhale
collection DOAJ
description Background: Chronic obstructive pulmonary disease (COPD) is a prevalent respiratory condition portrayed by persistent airflow limitation and correlated symptoms. Despite advances in treatment, COPD remains a significant global health burden, necessitating ongoing research to understand its long-standing impact on pulmonary function and quality of life (QoL). Methods: This longitudinal research enrolled 200 COPD and followed them over a 5-year period. Baseline assessments included spirometry to measure forced expiratory volume in one second (FEV1) and forced vital capacity (FVC), along with standardized questionnaires assessing QoL. Follow-up assessments were conducted annually, and statistical analysis was performed to examine changes in pulmonary function and QoL over time. Results: Significant declines in FEV1 and FVC were observed at each follow-up time point compared to the baseline, indicating progressive deterioration in lung function. QoL scores, as assessed by the St. George’s Respiratory Questionnaire and the COPD Assessment Test, also worsened progressively over the research period. Conclusion: Current conclusions underscore the progressive nature of COPD, highlighting the importance of proactive management strategies aimed at preserving lung function and improving QoL. Early intervention and ongoing monitoring are essential in optimizing outcomes for COPD subjects and reducing the disease burden on individuals and healthcare systems.
format Article
id doaj-art-463d52a4b6ed410a9dedf4f08edc8a52
institution OA Journals
issn 0976-4879
0975-7406
language English
publishDate 2024-08-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Journal of Pharmacy and Bioallied Sciences
spelling doaj-art-463d52a4b6ed410a9dedf4f08edc8a522025-08-20T01:48:10ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0976-48790975-74062024-08-0116Suppl 3S2737S273910.4103/jpbs.jpbs_252_24Assessment of Long-Term Pulmonary Function and Quality of Life in Patients with Chronic Obstructive Pulmonary Disease (COPD)Sanjay D. GabhaleMahavir Satishchand BagrechaMitali DashZeeshan SheikhS. BhuvaneshwariRangraze ImranTharini SatheeshBackground: Chronic obstructive pulmonary disease (COPD) is a prevalent respiratory condition portrayed by persistent airflow limitation and correlated symptoms. Despite advances in treatment, COPD remains a significant global health burden, necessitating ongoing research to understand its long-standing impact on pulmonary function and quality of life (QoL). Methods: This longitudinal research enrolled 200 COPD and followed them over a 5-year period. Baseline assessments included spirometry to measure forced expiratory volume in one second (FEV1) and forced vital capacity (FVC), along with standardized questionnaires assessing QoL. Follow-up assessments were conducted annually, and statistical analysis was performed to examine changes in pulmonary function and QoL over time. Results: Significant declines in FEV1 and FVC were observed at each follow-up time point compared to the baseline, indicating progressive deterioration in lung function. QoL scores, as assessed by the St. George’s Respiratory Questionnaire and the COPD Assessment Test, also worsened progressively over the research period. Conclusion: Current conclusions underscore the progressive nature of COPD, highlighting the importance of proactive management strategies aimed at preserving lung function and improving QoL. Early intervention and ongoing monitoring are essential in optimizing outcomes for COPD subjects and reducing the disease burden on individuals and healthcare systems.https://journals.lww.com/10.4103/jpbs.jpbs_252_24chronic obstructive pulmonary diseasecopdlongitudinal researchpulmonary functionqol
spellingShingle Sanjay D. Gabhale
Mahavir Satishchand Bagrecha
Mitali Dash
Zeeshan Sheikh
S. Bhuvaneshwari
Rangraze Imran
Tharini Satheesh
Assessment of Long-Term Pulmonary Function and Quality of Life in Patients with Chronic Obstructive Pulmonary Disease (COPD)
Journal of Pharmacy and Bioallied Sciences
chronic obstructive pulmonary disease
copd
longitudinal research
pulmonary function
qol
title Assessment of Long-Term Pulmonary Function and Quality of Life in Patients with Chronic Obstructive Pulmonary Disease (COPD)
title_full Assessment of Long-Term Pulmonary Function and Quality of Life in Patients with Chronic Obstructive Pulmonary Disease (COPD)
title_fullStr Assessment of Long-Term Pulmonary Function and Quality of Life in Patients with Chronic Obstructive Pulmonary Disease (COPD)
title_full_unstemmed Assessment of Long-Term Pulmonary Function and Quality of Life in Patients with Chronic Obstructive Pulmonary Disease (COPD)
title_short Assessment of Long-Term Pulmonary Function and Quality of Life in Patients with Chronic Obstructive Pulmonary Disease (COPD)
title_sort assessment of long term pulmonary function and quality of life in patients with chronic obstructive pulmonary disease copd
topic chronic obstructive pulmonary disease
copd
longitudinal research
pulmonary function
qol
url https://journals.lww.com/10.4103/jpbs.jpbs_252_24
work_keys_str_mv AT sanjaydgabhale assessmentoflongtermpulmonaryfunctionandqualityoflifeinpatientswithchronicobstructivepulmonarydiseasecopd
AT mahavirsatishchandbagrecha assessmentoflongtermpulmonaryfunctionandqualityoflifeinpatientswithchronicobstructivepulmonarydiseasecopd
AT mitalidash assessmentoflongtermpulmonaryfunctionandqualityoflifeinpatientswithchronicobstructivepulmonarydiseasecopd
AT zeeshansheikh assessmentoflongtermpulmonaryfunctionandqualityoflifeinpatientswithchronicobstructivepulmonarydiseasecopd
AT sbhuvaneshwari assessmentoflongtermpulmonaryfunctionandqualityoflifeinpatientswithchronicobstructivepulmonarydiseasecopd
AT rangrazeimran assessmentoflongtermpulmonaryfunctionandqualityoflifeinpatientswithchronicobstructivepulmonarydiseasecopd
AT tharinisatheesh assessmentoflongtermpulmonaryfunctionandqualityoflifeinpatientswithchronicobstructivepulmonarydiseasecopd