Mania following ketamine abuse

Yuan-Yuan Lu,1 Chieh-Hsin Lin,2,3 Hsien-Yuan Lane1,2,4 1Department of Psychiatry, China Medical University Hospital, 2Graduate Institute of Clinical Medical Science, China Medical University, Taichung, 3Department of Psychiatry, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College...

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Main Authors: Lu Y, Lin C, Lane H
Format: Article
Language:English
Published: Dove Medical Press 2016-01-01
Series:Neuropsychiatric Disease and Treatment
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Online Access:https://www.dovepress.com/mania-following-ketamine-abuse-peer-reviewed-fulltext-article-NDT
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author Lu Y
Lin C
Lane H
author_facet Lu Y
Lin C
Lane H
author_sort Lu Y
collection DOAJ
description Yuan-Yuan Lu,1 Chieh-Hsin Lin,2,3 Hsien-Yuan Lane1,2,4 1Department of Psychiatry, China Medical University Hospital, 2Graduate Institute of Clinical Medical Science, China Medical University, Taichung, 3Department of Psychiatry, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, 4Center for Drug Abuse and Addiction, China Medical University Hospital, Taichung, Taiwan Abstract: Ketamine, a noncompetitive antagonist of the N-methyl-d-aspartate (NMDA) receptor, has multiple clinical uses. On the other hand, ketamine abuse or recreational use has been gaining increasing attention. Induction of mania and psychotic symptoms has been reported in a patient receiving IV ketamine therapy for reflex sympathetic dystrophy. We here report a 26 year-old man who abused ketamine by inhalation for 12 months and developed manic-like symptoms after ketamine use. This case suggests a possible relationship between manic symptoms and ketamine abuse. To the best of our knowledge, this may be the first report regarding mania after recreational use of ketamine. Keywords: ketamine, mania, antidepressant, bipolar
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publishDate 2016-01-01
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series Neuropsychiatric Disease and Treatment
spelling doaj-art-463980b8104f48a790b1fb0497d4d7b02025-08-20T03:32:40ZengDove Medical PressNeuropsychiatric Disease and Treatment1178-20212016-01-01Volume 12Issue 123723925392Mania following ketamine abuseLu YLin CLane H0Department of PsychiatryYuan-Yuan Lu,1 Chieh-Hsin Lin,2,3 Hsien-Yuan Lane1,2,4 1Department of Psychiatry, China Medical University Hospital, 2Graduate Institute of Clinical Medical Science, China Medical University, Taichung, 3Department of Psychiatry, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, 4Center for Drug Abuse and Addiction, China Medical University Hospital, Taichung, Taiwan Abstract: Ketamine, a noncompetitive antagonist of the N-methyl-d-aspartate (NMDA) receptor, has multiple clinical uses. On the other hand, ketamine abuse or recreational use has been gaining increasing attention. Induction of mania and psychotic symptoms has been reported in a patient receiving IV ketamine therapy for reflex sympathetic dystrophy. We here report a 26 year-old man who abused ketamine by inhalation for 12 months and developed manic-like symptoms after ketamine use. This case suggests a possible relationship between manic symptoms and ketamine abuse. To the best of our knowledge, this may be the first report regarding mania after recreational use of ketamine. Keywords: ketamine, mania, antidepressant, bipolarhttps://www.dovepress.com/mania-following-ketamine-abuse-peer-reviewed-fulltext-article-NDTketaminemaniaantidepressantbipolarabuse
spellingShingle Lu Y
Lin C
Lane H
Mania following ketamine abuse
Neuropsychiatric Disease and Treatment
ketamine
mania
antidepressant
bipolar
abuse
title Mania following ketamine abuse
title_full Mania following ketamine abuse
title_fullStr Mania following ketamine abuse
title_full_unstemmed Mania following ketamine abuse
title_short Mania following ketamine abuse
title_sort mania following ketamine abuse
topic ketamine
mania
antidepressant
bipolar
abuse
url https://www.dovepress.com/mania-following-ketamine-abuse-peer-reviewed-fulltext-article-NDT
work_keys_str_mv AT luy maniafollowingketamineabuse
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AT laneh maniafollowingketamineabuse