Effect of artificial intelligence driven therapeutic lifestyle changes (AI-TLC) intervention on health behavior and health among obesity pregnant women in China: a randomized controlled trial protocol

IntroductionObesity has reached epidemic proportions globally, posing significant challenges to public health and economic stability. In China, the prevalence of obesity is increasing rapidly, particularly among pregnant women, who face unique risks due to the complex interplay between obesity and p...

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Main Authors: Xiaoyun Wang, Yang Bai, Wenzhuo Li, Chenxin Yang, Linjing Zhang, Hongyi Zhu, Rantong Bao, Yang Jiang, Fei Wang, Huanfang Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Public Health
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Online Access:https://www.frontiersin.org/articles/10.3389/fpubh.2025.1580060/full
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author Xiaoyun Wang
Yang Bai
Wenzhuo Li
Chenxin Yang
Linjing Zhang
Hongyi Zhu
Rantong Bao
Yang Jiang
Fei Wang
Fei Wang
Huanfang Wang
author_facet Xiaoyun Wang
Yang Bai
Wenzhuo Li
Chenxin Yang
Linjing Zhang
Hongyi Zhu
Rantong Bao
Yang Jiang
Fei Wang
Fei Wang
Huanfang Wang
author_sort Xiaoyun Wang
collection DOAJ
description IntroductionObesity has reached epidemic proportions globally, posing significant challenges to public health and economic stability. In China, the prevalence of obesity is increasing rapidly, particularly among pregnant women, who face unique risks due to the complex interplay between obesity and pregnancy outcomes. This study aims to evaluate the effectiveness of an Artificial Intelligence-driven Therapeutic Lifestyle Change (AI-TLC) intervention in improving health behaviors and outcomes among obese pregnant women in China.Methods and analysisThis randomized controlled trial will recruit pregnant women aged 18 years or older with a singleton pregnancy between 8 and 12 weeks of gestation and a pre-pregnancy BMI of ≥30.0 kg/m2. Participants will be randomly assigned to one of three groups: a manual intervention group, an AI intervention group, and a combined AI and manual intervention group. The intervention will focus on therapeutic lifestyle changes, including behavioral modifications, dietary adjustments, and physical activity promotion, supported by a multidisciplinary team. Primary outcomes will include maternal BMI, weight, and adverse pregnancy outcomes, while secondary outcomes will assess physiological indicators, quality of life, mental health, and lifestyle factors.ResultsThe study will evaluate the effects of health interventions on obese pregnant women through primary outcomes (e.g., BMI, weight, adverse pregnancy outcomes) and secondary outcomes (e.g., physiological indicators, quality of life, mental health) using various statistical methods. The results will provide insights into the intervention's effectiveness and cost-effectiveness across different socioeconomic groups.DiscussionThe anticipated findings are expected to demonstrate the efficacy of AI-TLC interventions in managing obesity during pregnancy. This study will contribute valuable evidence to the limited research on AI-based interventions for obese pregnant women, offering potential implications for the development of personalized, efficient, and innovative health strategies. The findings may also inform public health initiatives aimed at improving maternal and child health outcomes in the context of obesity.
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spelling doaj-art-4632143552f549e5bda02e808ed36fb62025-08-20T03:09:40ZengFrontiers Media S.A.Frontiers in Public Health2296-25652025-05-011310.3389/fpubh.2025.15800601580060Effect of artificial intelligence driven therapeutic lifestyle changes (AI-TLC) intervention on health behavior and health among obesity pregnant women in China: a randomized controlled trial protocolXiaoyun Wang0Yang Bai1Wenzhuo Li2Chenxin Yang3Linjing Zhang4Hongyi Zhu5Rantong Bao6Yang Jiang7Fei Wang8Fei Wang9Huanfang Wang10Pediatric Department, Inner Mongolia Maternal and Child Health Care Hospital, Hohhot, ChinaSchool of School of Public Administration and Policy, Renmin University of China, Beijing, ChinaMedical College, Qingdao University, Qingdao, Shandong, ChinaSchool of Health Management, China Medical University, Shenyang, ChinaXiang Ya Nursing School, Central South University, Changsha, Hunan, ChinaSchool of Nursing, Tianjin Medical University, Tianjin, ChinaDepartment of Quality Management, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, ChinaJitang College, North China University of Science and Technology, Tangshan, Hebei, ChinaShandong Key Laboratory of Reproductive Research and Birth Defect Prevention, Department of Gynecology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China0Department of Gynecology, Inner Mongolia Maternity and Child Health Care Hospital, Hohhot, ChinaPediatric Department, Inner Mongolia Maternal and Child Health Care Hospital, Hohhot, ChinaIntroductionObesity has reached epidemic proportions globally, posing significant challenges to public health and economic stability. In China, the prevalence of obesity is increasing rapidly, particularly among pregnant women, who face unique risks due to the complex interplay between obesity and pregnancy outcomes. This study aims to evaluate the effectiveness of an Artificial Intelligence-driven Therapeutic Lifestyle Change (AI-TLC) intervention in improving health behaviors and outcomes among obese pregnant women in China.Methods and analysisThis randomized controlled trial will recruit pregnant women aged 18 years or older with a singleton pregnancy between 8 and 12 weeks of gestation and a pre-pregnancy BMI of ≥30.0 kg/m2. Participants will be randomly assigned to one of three groups: a manual intervention group, an AI intervention group, and a combined AI and manual intervention group. The intervention will focus on therapeutic lifestyle changes, including behavioral modifications, dietary adjustments, and physical activity promotion, supported by a multidisciplinary team. Primary outcomes will include maternal BMI, weight, and adverse pregnancy outcomes, while secondary outcomes will assess physiological indicators, quality of life, mental health, and lifestyle factors.ResultsThe study will evaluate the effects of health interventions on obese pregnant women through primary outcomes (e.g., BMI, weight, adverse pregnancy outcomes) and secondary outcomes (e.g., physiological indicators, quality of life, mental health) using various statistical methods. The results will provide insights into the intervention's effectiveness and cost-effectiveness across different socioeconomic groups.DiscussionThe anticipated findings are expected to demonstrate the efficacy of AI-TLC interventions in managing obesity during pregnancy. This study will contribute valuable evidence to the limited research on AI-based interventions for obese pregnant women, offering potential implications for the development of personalized, efficient, and innovative health strategies. The findings may also inform public health initiatives aimed at improving maternal and child health outcomes in the context of obesity.https://www.frontiersin.org/articles/10.3389/fpubh.2025.1580060/fullobesitypregnant womenartificial intelligencetherapeutic lifestyle changerandomized controlled trial
spellingShingle Xiaoyun Wang
Yang Bai
Wenzhuo Li
Chenxin Yang
Linjing Zhang
Hongyi Zhu
Rantong Bao
Yang Jiang
Fei Wang
Fei Wang
Huanfang Wang
Effect of artificial intelligence driven therapeutic lifestyle changes (AI-TLC) intervention on health behavior and health among obesity pregnant women in China: a randomized controlled trial protocol
Frontiers in Public Health
obesity
pregnant women
artificial intelligence
therapeutic lifestyle change
randomized controlled trial
title Effect of artificial intelligence driven therapeutic lifestyle changes (AI-TLC) intervention on health behavior and health among obesity pregnant women in China: a randomized controlled trial protocol
title_full Effect of artificial intelligence driven therapeutic lifestyle changes (AI-TLC) intervention on health behavior and health among obesity pregnant women in China: a randomized controlled trial protocol
title_fullStr Effect of artificial intelligence driven therapeutic lifestyle changes (AI-TLC) intervention on health behavior and health among obesity pregnant women in China: a randomized controlled trial protocol
title_full_unstemmed Effect of artificial intelligence driven therapeutic lifestyle changes (AI-TLC) intervention on health behavior and health among obesity pregnant women in China: a randomized controlled trial protocol
title_short Effect of artificial intelligence driven therapeutic lifestyle changes (AI-TLC) intervention on health behavior and health among obesity pregnant women in China: a randomized controlled trial protocol
title_sort effect of artificial intelligence driven therapeutic lifestyle changes ai tlc intervention on health behavior and health among obesity pregnant women in china a randomized controlled trial protocol
topic obesity
pregnant women
artificial intelligence
therapeutic lifestyle change
randomized controlled trial
url https://www.frontiersin.org/articles/10.3389/fpubh.2025.1580060/full
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