Polarimetric Detection of Enantioselective Adsorption by Chiral Au Nanoparticles – Effects of Temperature, Wavelength and Size

R- and S-propylene oxide (PO) have been shown to interact enantiospecifically with the chiral surfaces of Au nanopar‐ ticles (NPs) modified with D- or L-cysteine (cys). This enantiospecific interaction has been detected using optical polarimetry measurements made on solutions of the D- or L-cys modi...

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Main Authors: Nisha Shukla, Nathaniel Ondeck, Nathan Khosla, Steven Klara, Alexander Petti, Andrew Gellman
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Nanomaterials and Nanotechnology
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Online Access:http://www.intechopen.com/journals/nanomaterials_and_nanotechnology/polarimetric-detection-of-enantioselective-adsorption-by-chiral-au-nanoparticles-ndash-effects-of-te
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author Nisha Shukla
Nathaniel Ondeck
Nathan Khosla
Steven Klara
Alexander Petti
Andrew Gellman
author_facet Nisha Shukla
Nathaniel Ondeck
Nathan Khosla
Steven Klara
Alexander Petti
Andrew Gellman
author_sort Nisha Shukla
collection DOAJ
description R- and S-propylene oxide (PO) have been shown to interact enantiospecifically with the chiral surfaces of Au nanopar‐ ticles (NPs) modified with D- or L-cysteine (cys). This enantiospecific interaction has been detected using optical polarimetry measurements made on solutions of the D- or L-cys modified Au (cys/Au) NPs during addition of racemic PO. The selective adsorption of one enantiomer of the PO onto the cys/Au NP surfaces results in a net rotation of light during addition of the racemic PO to the solution. In order to optimize the conditions used for making these measurements and to quantify enantiospecific adsorption onto chiral NPs, this work has measured the effect of temperature, wavelength and Au NP size on optical rotation by solutions containing D- or L-cys/Au NPs and racemic PO. Increasing temperature, decreasing wave‐ length and decreasing NP size result in larger optical rotations.
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spelling doaj-art-462bed20e7c549e5a313f3b37565f1bf2025-08-20T02:37:49ZengWileyNanomaterials and Nanotechnology1847-98042015-01-0151http://dx.doi.org/10.5772/6010948192Polarimetric Detection of Enantioselective Adsorption by Chiral Au Nanoparticles – Effects of Temperature, Wavelength and SizeNisha ShuklaNathaniel OndeckNathan KhoslaSteven KlaraAlexander PettiAndrew GellmanR- and S-propylene oxide (PO) have been shown to interact enantiospecifically with the chiral surfaces of Au nanopar‐ ticles (NPs) modified with D- or L-cysteine (cys). This enantiospecific interaction has been detected using optical polarimetry measurements made on solutions of the D- or L-cys modified Au (cys/Au) NPs during addition of racemic PO. The selective adsorption of one enantiomer of the PO onto the cys/Au NP surfaces results in a net rotation of light during addition of the racemic PO to the solution. In order to optimize the conditions used for making these measurements and to quantify enantiospecific adsorption onto chiral NPs, this work has measured the effect of temperature, wavelength and Au NP size on optical rotation by solutions containing D- or L-cys/Au NPs and racemic PO. Increasing temperature, decreasing wave‐ length and decreasing NP size result in larger optical rotations.http://www.intechopen.com/journals/nanomaterials_and_nanotechnology/polarimetric-detection-of-enantioselective-adsorption-by-chiral-au-nanoparticles-ndash-effects-of-techiralnanoparticleenantioselectiveadsorp‐ tionseparationAu
spellingShingle Nisha Shukla
Nathaniel Ondeck
Nathan Khosla
Steven Klara
Alexander Petti
Andrew Gellman
Polarimetric Detection of Enantioselective Adsorption by Chiral Au Nanoparticles – Effects of Temperature, Wavelength and Size
Nanomaterials and Nanotechnology
chiral
nanoparticle
enantioselective
adsorp‐ tion
separation
Au
title Polarimetric Detection of Enantioselective Adsorption by Chiral Au Nanoparticles – Effects of Temperature, Wavelength and Size
title_full Polarimetric Detection of Enantioselective Adsorption by Chiral Au Nanoparticles – Effects of Temperature, Wavelength and Size
title_fullStr Polarimetric Detection of Enantioselective Adsorption by Chiral Au Nanoparticles – Effects of Temperature, Wavelength and Size
title_full_unstemmed Polarimetric Detection of Enantioselective Adsorption by Chiral Au Nanoparticles – Effects of Temperature, Wavelength and Size
title_short Polarimetric Detection of Enantioselective Adsorption by Chiral Au Nanoparticles – Effects of Temperature, Wavelength and Size
title_sort polarimetric detection of enantioselective adsorption by chiral au nanoparticles effects of temperature wavelength and size
topic chiral
nanoparticle
enantioselective
adsorp‐ tion
separation
Au
url http://www.intechopen.com/journals/nanomaterials_and_nanotechnology/polarimetric-detection-of-enantioselective-adsorption-by-chiral-au-nanoparticles-ndash-effects-of-te
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AT nathankhosla polarimetricdetectionofenantioselectiveadsorptionbychiralaunanoparticleseffectsoftemperaturewavelengthandsize
AT stevenklara polarimetricdetectionofenantioselectiveadsorptionbychiralaunanoparticleseffectsoftemperaturewavelengthandsize
AT alexanderpetti polarimetricdetectionofenantioselectiveadsorptionbychiralaunanoparticleseffectsoftemperaturewavelengthandsize
AT andrewgellman polarimetricdetectionofenantioselectiveadsorptionbychiralaunanoparticleseffectsoftemperaturewavelengthandsize