AKR1B10 as a novel prognostic biomarker linking methylation and immune escape in hepatocellular carcinoma

AKR1B10 as a novel prognostic biomarker linking methylation and immune escape in hepatocellular carcinoma

Abstract Objective Liver cancer continues to be a significant challenge among malignancies today. Hepatocellular carcinoma is one of the cancers that exhibits a marked upregulation of AKR1B10, an enzyme involved in cellular metabolism. The advancement of HCC treatment indicates that immunotherapy an...

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Bibliographic Details
Main Authors: Muhammad Naveed Khan, Mao Binli, Hu Juan, Shi Mengjia, Wang Shunyao, Xiaosong Li
Format: Article
Language:English
Published: Springer 2025-08-01
Series:Discover Oncology
Subjects:
AKR1B10
Biomarker
Epigenomics
Immune escape
liver cancer
Online Access:https://doi.org/10.1007/s12672-025-03017-w
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