LncRNA NEAT1-206 regulates autophagy of human umbilical cord mesenchymal stem cells through the WNT5A/Ca2+ signaling pathway under senescence stress

LncRNA NEAT1-206 regulates autophagy of human umbilical cord mesenchymal stem cells through the WNT5A/Ca2+ signaling pathway under senescence stress

Stem cells are crucial for maintaining bodily stability, but their regenerative abilities decline with age. This decline is marked by reduced proliferation and differentiation capacities of stem cells, as well as exhaustion of the stem cell pool. The accumulation of aged mesenchymal stem cells (MSCs...

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Bibliographic Details
Main Authors: Weili Wang, Yongyu Wang, Chunchun Duan, Wenjing Tian, Liyang Gao
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-04-01
Series:Non-coding RNA Research
Subjects:
LncRNA NEAT1-206
Cell senescence
Autophagy
WNT5A/Ca2+ signaling pathway
Mesenchymal stem cells
Online Access:http://www.sciencedirect.com/science/article/pii/S246805402400177X
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