Intrapleural Tenecteplase for Complicated Parapneumonic Pleural Effusion
Intrapleural thrombolytics have shown promising results in complicated parapneumonic pleural effusions reducing the need for surgical interventions. Until now, studies have evaluated primarily streptokinase, urokinase, and recently, alteplase. In this case series, we share our experience with tenect...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Pulmonology |
| Online Access: | http://dx.doi.org/10.1155/2021/2206692 |
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| _version_ | 1849407038223810560 |
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| author | Husain Kadhem Kannan Sridharan Naser Naser |
| author_facet | Husain Kadhem Kannan Sridharan Naser Naser |
| author_sort | Husain Kadhem |
| collection | DOAJ |
| description | Intrapleural thrombolytics have shown promising results in complicated parapneumonic pleural effusions reducing the need for surgical interventions. Until now, studies have evaluated primarily streptokinase, urokinase, and recently, alteplase. In this case series, we share our experience with tenecteplase—a tissue-specific plasminogen activator in 15 patients. We observed that tenecteplase is effective in 14/15 (93.3%) of our patients, and none of them had any bleeding episodes. |
| format | Article |
| id | doaj-art-460e53beb45f45dbb34ad5f208157c77 |
| institution | Kabale University |
| issn | 2090-6846 2090-6854 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pulmonology |
| spelling | doaj-art-460e53beb45f45dbb34ad5f208157c772025-08-20T03:36:12ZengWileyCase Reports in Pulmonology2090-68462090-68542021-01-01202110.1155/2021/22066922206692Intrapleural Tenecteplase for Complicated Parapneumonic Pleural EffusionHusain Kadhem0Kannan Sridharan1Naser Naser2Department of Internal Medicine, Salmaniya Medical Complex, Manama, BahrainDepartment of Pharmacology & Therapeutics, College of Medicine & Medical Sciences, Arabian Gulf University, Manama, BahrainDepartment of Internal Medicine, Salmaniya Medical Complex, Manama, BahrainIntrapleural thrombolytics have shown promising results in complicated parapneumonic pleural effusions reducing the need for surgical interventions. Until now, studies have evaluated primarily streptokinase, urokinase, and recently, alteplase. In this case series, we share our experience with tenecteplase—a tissue-specific plasminogen activator in 15 patients. We observed that tenecteplase is effective in 14/15 (93.3%) of our patients, and none of them had any bleeding episodes.http://dx.doi.org/10.1155/2021/2206692 |
| spellingShingle | Husain Kadhem Kannan Sridharan Naser Naser Intrapleural Tenecteplase for Complicated Parapneumonic Pleural Effusion Case Reports in Pulmonology |
| title | Intrapleural Tenecteplase for Complicated Parapneumonic Pleural Effusion |
| title_full | Intrapleural Tenecteplase for Complicated Parapneumonic Pleural Effusion |
| title_fullStr | Intrapleural Tenecteplase for Complicated Parapneumonic Pleural Effusion |
| title_full_unstemmed | Intrapleural Tenecteplase for Complicated Parapneumonic Pleural Effusion |
| title_short | Intrapleural Tenecteplase for Complicated Parapneumonic Pleural Effusion |
| title_sort | intrapleural tenecteplase for complicated parapneumonic pleural effusion |
| url | http://dx.doi.org/10.1155/2021/2206692 |
| work_keys_str_mv | AT husainkadhem intrapleuraltenecteplaseforcomplicatedparapneumonicpleuraleffusion AT kannansridharan intrapleuraltenecteplaseforcomplicatedparapneumonicpleuraleffusion AT nasernaser intrapleuraltenecteplaseforcomplicatedparapneumonicpleuraleffusion |