The clinical observation of Shenxuening vs.iron saccbarate in treating stable renal anemia in the patients undergoing hemodialysis
Objective To investigate the difference between Shenxuening(SXN,po) and iron saccharateCIS,iv) in treating renal anemia in the patients undergoing hemodialysis.Methods Thirteen patients in the Zhaoqing First People’s Hospital with hemoglobin ranging from 100 to 130 g/L were enrolled and retrospectiv...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | zho |
| Published: |
Editorial Department of Journal of Clinical Nephrology
2016-01-01
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| Series: | Linchuang shenzangbing zazhi |
| Subjects: | |
| Online Access: | http://www.lcszb.com/thesisDetails?columnId=57918788&Fpath=home&index=0 |
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| Summary: | Objective To investigate the difference between Shenxuening(SXN,po) and iron saccharateCIS,iv) in treating renal anemia in the patients undergoing hemodialysis.Methods Thirteen patients in the Zhaoqing First People’s Hospital with hemoglobin ranging from 100 to 130 g/L were enrolled and retrospectively observed in this research.Seven patients were assigned into SXN group treated with SXN(0.5 g/day po,trice one day) for 3 months,meanwhile,6 patients in IS group received IS(100 mg every week) intravenously.The baseline data including age,gender and volume of ESA were recorded.The index of iron metabolism(ferritin,serum iron,total iron biding capacity,transferrin saturation),anemia(hemoglobin,RBC,HCT),Hs-CRP,and liver and kidney functions were collected in the beginning and end of the research.Results No differences were found between the two groups before the treatment After treatment,the volume of Hb was similar between the two groups[(116.57± 12.21) vs.(106.00 ± 15.36) g/L],but the serum iron[(14.70 ± 5.30) vs.(6.25 ±2.41) μmol/L]and transferrin saturation(0.45 ± 0.20 vs.0.36 + 0.18) were higher,and Hs-CRP(median 2.07 vs.7.95 ng/ml,P= 0.022) was lower in SXN group than in IS group.Furthermore,the level of Hs-CRP was higher in IS group than that after treatment Cmedian 4.17 vs.7.95,P =0.028).Conclusions SXN and IS were effective in the treatment of renal anemia in stable stage,and SXN might have less risk to result in micro-inflammation. |
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| ISSN: | 1671-2390 |