Mesenchymal stem cell-mediated adipogenic transformation: a key driver of oral squamous cell carcinoma progression

Mesenchymal stem cell-mediated adipogenic transformation: a key driver of oral squamous cell carcinoma progression

Abstract Background Interaction between mesenchymal stem cells (MSCs) and oral squamous cell carcinoma (OSCC) cells plays a major role in OSCC progression. However, little is known about adipogenic differentiation alteration in OSCC-derived MSCs (OSCC-MSCs) and how these alterations affect OSCC grow...

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Bibliographic Details
Main Authors:	Yiting Shao, Yu Du, Zheng Chen, Lei Xiang, Shaoqin Tu, Yi Feng, Yuluan Hou, Xiaoxing Kou, Hong Ai
Format:	Article
Language:	English
Published:	BMC 2025-01-01
Series:	Stem Cell Research & Therapy
Subjects:	Adipogenic differentiation Mesenchymal stem cells Tumor-derived MSCs Fatty acid synthase Oral squamous cell carcinoma
Online Access:	https://doi.org/10.1186/s13287-025-04132-9
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