Trends in cerebrovascular diseases, pelvic and hip fractures-related mortality among older adults in the United States from 1999–2020

Background: We aim to evaluate trends in Cerebrovascular Diseases (CVD) and pelvic and hip fractures (PHF)-related deaths among adults (≥ 65 years) in the US from 1999 to 2020, highlighting the differences based on demographics. Methods: We analyzed death certificates from the CDC WONDER (Centers fo...

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Main Authors: Rija Shakil, MBBS, Ahmed Mustafa Rashid, MBBS, Muhammad Haleem Nasar, MBBS, Marium Omair Mirza, MBBS, Muttia Abdul Sattar, MBBS, Taha Abdul Ahad, MBBS, Sehar Ul Duaa, MBBS, Rana Usman Anwar, MD, Prinka Perswani, MD
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Archives of Gerontology and Geriatrics Plus
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Online Access:http://www.sciencedirect.com/science/article/pii/S2950307824000821
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author Rija Shakil, MBBS
Ahmed Mustafa Rashid, MBBS
Muhammad Haleem Nasar, MBBS
Marium Omair Mirza, MBBS
Muttia Abdul Sattar, MBBS
Taha Abdul Ahad, MBBS
Sehar Ul Duaa, MBBS
Rana Usman Anwar, MD
Prinka Perswani, MD
author_facet Rija Shakil, MBBS
Ahmed Mustafa Rashid, MBBS
Muhammad Haleem Nasar, MBBS
Marium Omair Mirza, MBBS
Muttia Abdul Sattar, MBBS
Taha Abdul Ahad, MBBS
Sehar Ul Duaa, MBBS
Rana Usman Anwar, MD
Prinka Perswani, MD
author_sort Rija Shakil, MBBS
collection DOAJ
description Background: We aim to evaluate trends in Cerebrovascular Diseases (CVD) and pelvic and hip fractures (PHF)-related deaths among adults (≥ 65 years) in the US from 1999 to 2020, highlighting the differences based on demographics. Methods: We analyzed death certificates from the CDC WONDER (Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research) database spanning 1999 to 2020, related to CVD and PHF in people aged ≥65 years. Age-Adjusted Mortality Rates (AAMRs) per 100,000 persons and annual percent change (APC) were computed using Joinpoint software. The analysis was organized by year, sex, race/ethnicity, and geographic distribution (states, census regions, metropolitan/non-metropolitan areas). Results: The AAMR for CVD and PHF decreased from 4.5 in 1999 to 2.2 in 2020. Similar pattern was observed for AAMR in females and males. Highest overall AAMR was noted in Non-Hispanic (NH) White adults (3.2) and lowest in African Americans (1.2). States of Wyoming, Alaska, North Dakota, Oregon, and Minnesota were in the top 90th percentile of AAMR while Florida, District of Columbia, Nevada, Arizona, and New York were in lower 10th percentile. Highest AAMRs were observed in Midwestern census region, followed by Western, Southern and Northeastern regions (3.8,2.8,2.7, and 1.9 respectively). Nonmetropolitan areas had a higher AAMR (4.4 vs 2.5) than metropolitan areas. Conclusion: The CVDs and PHF related mortality rate increased steadily after 2014. NH white females were found to be at increased risk. A research-based management plan needs to be devised for post stroke pelvic and hip fractures in elderly.
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spelling doaj-art-45f52eb50b6a41cfbe0b64b2c9ecd7c42025-08-20T02:38:39ZengElsevierArchives of Gerontology and Geriatrics Plus2950-30782024-12-011410008510.1016/j.aggp.2024.100085Trends in cerebrovascular diseases, pelvic and hip fractures-related mortality among older adults in the United States from 1999–2020Rija Shakil, MBBS0Ahmed Mustafa Rashid, MBBS1Muhammad Haleem Nasar, MBBS2Marium Omair Mirza, MBBS3Muttia Abdul Sattar, MBBS4Taha Abdul Ahad, MBBS5Sehar Ul Duaa, MBBS6Rana Usman Anwar, MD7Prinka Perswani, MD8Department of Medicine, Dow University of Health Sciences, Mission Rd, New Labor Colony Nanakwara, Karachi, Karachi City, Sindh 74200, Pakistan; Corresponding author at: 109 Bellamy Mill Drive, Holly Springs, NC 27540, United States.Department of Medicine, Jinnah Sindh Medical University, Rafiqui H.J, Iqbal Shaheed Rd, Karachi Cantonment Karachi, Sindh 75510, PakistanDepartment of Medicine, Northwest School of Medicine, Plot #8, Sector A-2, Phase 5 Hayatabad, Peshawar, PakistanDepartment of Medicine, Ziauddin Medical University, 4/B, Shahrah-e-Ghalib, Block 6, Clifton Karachi, 75600 Sindh, PakistanDepartment of Medicine, Karachi Medical and Dental College, North Nazimabad, Block M, Karachi 74600 Sindh, PakistanDepartment of Medicine, Jinnah Sindh Medical University, Rafiqui H.J, Iqbal Shaheed Rd, Karachi Cantonment Karachi, Sindh 75510, PakistanDepartment of Medicine, Services Institute of Medical Sciences, Lahore 54000, PakistanDepartment of Family Medicine, Memorial Medical Center, 2669N Scenic Dr, Alamogordo, New Mexico, NM 88310, United StatesDepartment of Internal Medicine, University of California Riverside School of Medicine, 92521 Botanic Gardens Dr, Riverside, CA 92507, United StatesBackground: We aim to evaluate trends in Cerebrovascular Diseases (CVD) and pelvic and hip fractures (PHF)-related deaths among adults (≥ 65 years) in the US from 1999 to 2020, highlighting the differences based on demographics. Methods: We analyzed death certificates from the CDC WONDER (Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research) database spanning 1999 to 2020, related to CVD and PHF in people aged ≥65 years. Age-Adjusted Mortality Rates (AAMRs) per 100,000 persons and annual percent change (APC) were computed using Joinpoint software. The analysis was organized by year, sex, race/ethnicity, and geographic distribution (states, census regions, metropolitan/non-metropolitan areas). Results: The AAMR for CVD and PHF decreased from 4.5 in 1999 to 2.2 in 2020. Similar pattern was observed for AAMR in females and males. Highest overall AAMR was noted in Non-Hispanic (NH) White adults (3.2) and lowest in African Americans (1.2). States of Wyoming, Alaska, North Dakota, Oregon, and Minnesota were in the top 90th percentile of AAMR while Florida, District of Columbia, Nevada, Arizona, and New York were in lower 10th percentile. Highest AAMRs were observed in Midwestern census region, followed by Western, Southern and Northeastern regions (3.8,2.8,2.7, and 1.9 respectively). Nonmetropolitan areas had a higher AAMR (4.4 vs 2.5) than metropolitan areas. Conclusion: The CVDs and PHF related mortality rate increased steadily after 2014. NH white females were found to be at increased risk. A research-based management plan needs to be devised for post stroke pelvic and hip fractures in elderly.http://www.sciencedirect.com/science/article/pii/S2950307824000821Cerebrovascular disordersPelvic hip fracturesMortalityDisparities
spellingShingle Rija Shakil, MBBS
Ahmed Mustafa Rashid, MBBS
Muhammad Haleem Nasar, MBBS
Marium Omair Mirza, MBBS
Muttia Abdul Sattar, MBBS
Taha Abdul Ahad, MBBS
Sehar Ul Duaa, MBBS
Rana Usman Anwar, MD
Prinka Perswani, MD
Trends in cerebrovascular diseases, pelvic and hip fractures-related mortality among older adults in the United States from 1999–2020
Archives of Gerontology and Geriatrics Plus
Cerebrovascular disorders
Pelvic hip fractures
Mortality
Disparities
title Trends in cerebrovascular diseases, pelvic and hip fractures-related mortality among older adults in the United States from 1999–2020
title_full Trends in cerebrovascular diseases, pelvic and hip fractures-related mortality among older adults in the United States from 1999–2020
title_fullStr Trends in cerebrovascular diseases, pelvic and hip fractures-related mortality among older adults in the United States from 1999–2020
title_full_unstemmed Trends in cerebrovascular diseases, pelvic and hip fractures-related mortality among older adults in the United States from 1999–2020
title_short Trends in cerebrovascular diseases, pelvic and hip fractures-related mortality among older adults in the United States from 1999–2020
title_sort trends in cerebrovascular diseases pelvic and hip fractures related mortality among older adults in the united states from 1999 2020
topic Cerebrovascular disorders
Pelvic hip fractures
Mortality
Disparities
url http://www.sciencedirect.com/science/article/pii/S2950307824000821
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