Ocular Biometric Characteristics of Chinese with History of Acute Angle Closure

Purpose. To investigate the biometric characteristics of Chinese patients with a history of acute angle closure (AAC). Methods. In this clinic-based, retrospective, observational, cross-sectional study, biometric parameters of eyes were acquired from a general population of Chinese adults. The crowd...

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Main Authors: Wei-ran Niu, Chun-qiong Dong, Xi Zhang, Yi-fan Feng, Fei Yuan
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2018/5835791
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author Wei-ran Niu
Chun-qiong Dong
Xi Zhang
Yi-fan Feng
Fei Yuan
author_facet Wei-ran Niu
Chun-qiong Dong
Xi Zhang
Yi-fan Feng
Fei Yuan
author_sort Wei-ran Niu
collection DOAJ
description Purpose. To investigate the biometric characteristics of Chinese patients with a history of acute angle closure (AAC). Methods. In this clinic-based, retrospective, observational, cross-sectional study, biometric parameters of eyes were acquired from a general population of Chinese adults. The crowding value (defined as lens thickness (LT); central corneal thickness (CCT); anterior chamber depth (ACD)/axial length (AL)) was calculated for each patient. Logistic regression analysis was performed to identify risk factors for AAC. Receiver operating characteristic (ROC) curves were plotted, and biometric variables were compared to compile a risk assessment for AAC. Result. This study included 1500 healthy subjects (2624 eyes, mean age of 66.54 ± 15.82 years) and 107 subjects with AAC (202 eyes, mean age of 70.01 ± 11.05 years). Eyes with AAC had thicker lens (P≤0.001), shallower anterior chamber depth (P≤0.001), and shorter axial length (P≤0.001) than healthy eyes. Logistic regression analysis and ROC curve analysis indicated that a crowding value above 0.13 was a significant (P<0.05) risk factor for the development of AAC. Conclusions. Biometric parameters were significantly different between the eyes from the AAC group to the normal group. Ocular crowding value might be a new noncontact screening method to assess the risk of AAC in adults.
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series Journal of Ophthalmology
spelling doaj-art-45f2f249d99b4cdfb503a6f1361938512025-08-20T03:36:12ZengWileyJournal of Ophthalmology2090-004X2090-00582018-01-01201810.1155/2018/58357915835791Ocular Biometric Characteristics of Chinese with History of Acute Angle ClosureWei-ran Niu0Chun-qiong Dong1Xi Zhang2Yi-fan Feng3Fei Yuan4Department of Ophthalmology, Zhongshan Hospital of Fudan University, Shanghai 200032, ChinaDepartment of Ophthalmology, Zhongshan Hospital of Fudan University, Shanghai 200032, ChinaDepartment of Ophthalmology, Zhongshan Hospital of Fudan University, Shanghai 200032, ChinaDepartment of Ophthalmology, Zhongshan Hospital of Fudan University, Shanghai 200032, ChinaDepartment of Ophthalmology, Zhongshan Hospital of Fudan University, Shanghai 200032, ChinaPurpose. To investigate the biometric characteristics of Chinese patients with a history of acute angle closure (AAC). Methods. In this clinic-based, retrospective, observational, cross-sectional study, biometric parameters of eyes were acquired from a general population of Chinese adults. The crowding value (defined as lens thickness (LT); central corneal thickness (CCT); anterior chamber depth (ACD)/axial length (AL)) was calculated for each patient. Logistic regression analysis was performed to identify risk factors for AAC. Receiver operating characteristic (ROC) curves were plotted, and biometric variables were compared to compile a risk assessment for AAC. Result. This study included 1500 healthy subjects (2624 eyes, mean age of 66.54 ± 15.82 years) and 107 subjects with AAC (202 eyes, mean age of 70.01 ± 11.05 years). Eyes with AAC had thicker lens (P≤0.001), shallower anterior chamber depth (P≤0.001), and shorter axial length (P≤0.001) than healthy eyes. Logistic regression analysis and ROC curve analysis indicated that a crowding value above 0.13 was a significant (P<0.05) risk factor for the development of AAC. Conclusions. Biometric parameters were significantly different between the eyes from the AAC group to the normal group. Ocular crowding value might be a new noncontact screening method to assess the risk of AAC in adults.http://dx.doi.org/10.1155/2018/5835791
spellingShingle Wei-ran Niu
Chun-qiong Dong
Xi Zhang
Yi-fan Feng
Fei Yuan
Ocular Biometric Characteristics of Chinese with History of Acute Angle Closure
Journal of Ophthalmology
title Ocular Biometric Characteristics of Chinese with History of Acute Angle Closure
title_full Ocular Biometric Characteristics of Chinese with History of Acute Angle Closure
title_fullStr Ocular Biometric Characteristics of Chinese with History of Acute Angle Closure
title_full_unstemmed Ocular Biometric Characteristics of Chinese with History of Acute Angle Closure
title_short Ocular Biometric Characteristics of Chinese with History of Acute Angle Closure
title_sort ocular biometric characteristics of chinese with history of acute angle closure
url http://dx.doi.org/10.1155/2018/5835791
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AT yifanfeng ocularbiometriccharacteristicsofchinesewithhistoryofacuteangleclosure
AT feiyuan ocularbiometriccharacteristicsofchinesewithhistoryofacuteangleclosure