Impacts of Forest Bathing (Shinrin-Yoku) in Female Participants with Depression/Depressive Tendencies

Background: It has been reported that forest bathing significantly reduced negative emotions and increased the positive feelings in both healthy males and females, as well as increasing blood serotonin in healthy males, indicating the potential for a beneficial effect on depressive status. However,...

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Main Authors: Qing Li, Norimasa Takayama, Masao Katsumata, Hiroshi Takayama, Yukako Kimura, Shigeyoshi Kumeda, Takashi Miura, Tetsuya Ichimiya, Ruei Tan, Haruka Shimomura, Amane Tateno, Tsunemi Kitagawa, Yoichiro Aoyagi, Michiko Imai
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Diseases
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Online Access:https://www.mdpi.com/2079-9721/13/4/100
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author Qing Li
Norimasa Takayama
Masao Katsumata
Hiroshi Takayama
Yukako Kimura
Shigeyoshi Kumeda
Takashi Miura
Tetsuya Ichimiya
Ruei Tan
Haruka Shimomura
Amane Tateno
Tsunemi Kitagawa
Yoichiro Aoyagi
Michiko Imai
author_facet Qing Li
Norimasa Takayama
Masao Katsumata
Hiroshi Takayama
Yukako Kimura
Shigeyoshi Kumeda
Takashi Miura
Tetsuya Ichimiya
Ruei Tan
Haruka Shimomura
Amane Tateno
Tsunemi Kitagawa
Yoichiro Aoyagi
Michiko Imai
author_sort Qing Li
collection DOAJ
description Background: It has been reported that forest bathing significantly reduced negative emotions and increased the positive feelings in both healthy males and females, as well as increasing blood serotonin in healthy males, indicating the potential for a beneficial effect on depressive status. However, an improvement effect of forest bathing on participants with depression has not been reported so far. Therefore, in order to fill this gap, this study examined the effect of forest bathing on depression in female participants with depression/depressive tendencies. Methods: Thirty-one females aged 40.1 ± 2.4 years with depression/depressive tendencies were recruited after obtaining informed consent. The study employed a randomized crossover design to compare forest bathing with city walking. They participated in day trips to a Japanese cypress forest park and to a city area of Nagano Prefecture as a control in June 2023. On both trips, they walked 2.5 km (for 90 min) in the morning and afternoon, respectively, for a total of 5.0 km per day. Blood samples were taken at 4 pm for the measurements before forest bathing on the first day and after the walking in forest and unban sites on the second and third days, at the same hospital. Concentrations of oxytocin, IGF-1, serotonin and lactic acid in blood were measured. SDS scores were calculated and the POMS test and questionnaires for subjective fatigue symptoms and sleep quality were administered before and after each trip. Temperature, humidity and illuminance were also measured in the forest and urban environments. The Nippon Medical School Central Ethics Committee approved this study. Results: Forest bathing significantly decreased SDS scores compared to city walk and the baseline, and the effect lasted for one week after forest bathing. Forest bathing also significantly increased the concentrations of blood serotonin in participants who were not taking antidepressants, significantly increased the levels of oxytocin and IGF-1 in blood, significantly increased the scores for positive feelings, and reduced the scores for negative emotions compared with city walking in the POMS test. In addition, forest bathing reduced subjective fatigue symptoms and improved sleep quality. Conclusions: These findings provided scientific evidence to contribute to understanding forest bathing as a potential intervention for preventing depression, and future research on males should further explore these effects.
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spelling doaj-art-45f1e54ce21046f19983d747f21948402025-08-20T02:17:24ZengMDPI AGDiseases2079-97212025-03-0113410010.3390/diseases13040100Impacts of Forest Bathing (Shinrin-Yoku) in Female Participants with Depression/Depressive TendenciesQing Li0Norimasa Takayama1Masao Katsumata2Hiroshi Takayama3Yukako Kimura4Shigeyoshi Kumeda5Takashi Miura6Tetsuya Ichimiya7Ruei Tan8Haruka Shimomura9Amane Tateno10Tsunemi Kitagawa11Yoichiro Aoyagi12Michiko Imai13Department of Rehabilitation Medicine, Graduate School of Medicine, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, JapanForestry and Forest Products Research Institute, Forest Research and Management Organization, Tsukuba 300-1244, JapanNursing School, Nippon Medical School, Chiba 270-1613, JapanTakayama Orthopedic Clinic, Tokyo 617-0814, Japanitswellness org, Tokyo 305-8687, JapanNagano Prefectural Kiso Hospital, Nagano 397-0001, JapanAgematsu Town Office, Nagano 399-5601, JapanIchimiya Mental Clinic, Tokyo 110-0005, JapanTan Clinic, Tokyo 214-0001, JapanHojo Clinic Mizonokuchi, Kawasaki 213-0011, JapanDepartment of Neuropsychiatry, Graduate School of Medicine, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, JapanDepartment of Rehabilitation Medicine, Graduate School of Medicine, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, JapanDepartment of Rehabilitation Medicine, Graduate School of Medicine, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, JapanINFOM (International Society of Nature and Forest Medicine), Tokyo, JapanBackground: It has been reported that forest bathing significantly reduced negative emotions and increased the positive feelings in both healthy males and females, as well as increasing blood serotonin in healthy males, indicating the potential for a beneficial effect on depressive status. However, an improvement effect of forest bathing on participants with depression has not been reported so far. Therefore, in order to fill this gap, this study examined the effect of forest bathing on depression in female participants with depression/depressive tendencies. Methods: Thirty-one females aged 40.1 ± 2.4 years with depression/depressive tendencies were recruited after obtaining informed consent. The study employed a randomized crossover design to compare forest bathing with city walking. They participated in day trips to a Japanese cypress forest park and to a city area of Nagano Prefecture as a control in June 2023. On both trips, they walked 2.5 km (for 90 min) in the morning and afternoon, respectively, for a total of 5.0 km per day. Blood samples were taken at 4 pm for the measurements before forest bathing on the first day and after the walking in forest and unban sites on the second and third days, at the same hospital. Concentrations of oxytocin, IGF-1, serotonin and lactic acid in blood were measured. SDS scores were calculated and the POMS test and questionnaires for subjective fatigue symptoms and sleep quality were administered before and after each trip. Temperature, humidity and illuminance were also measured in the forest and urban environments. The Nippon Medical School Central Ethics Committee approved this study. Results: Forest bathing significantly decreased SDS scores compared to city walk and the baseline, and the effect lasted for one week after forest bathing. Forest bathing also significantly increased the concentrations of blood serotonin in participants who were not taking antidepressants, significantly increased the levels of oxytocin and IGF-1 in blood, significantly increased the scores for positive feelings, and reduced the scores for negative emotions compared with city walking in the POMS test. In addition, forest bathing reduced subjective fatigue symptoms and improved sleep quality. Conclusions: These findings provided scientific evidence to contribute to understanding forest bathing as a potential intervention for preventing depression, and future research on males should further explore these effects.https://www.mdpi.com/2079-9721/13/4/100depressionfemale participantsforest bathinginsulin-like growth factor I (IGF-1)sleepoxytocin
spellingShingle Qing Li
Norimasa Takayama
Masao Katsumata
Hiroshi Takayama
Yukako Kimura
Shigeyoshi Kumeda
Takashi Miura
Tetsuya Ichimiya
Ruei Tan
Haruka Shimomura
Amane Tateno
Tsunemi Kitagawa
Yoichiro Aoyagi
Michiko Imai
Impacts of Forest Bathing (Shinrin-Yoku) in Female Participants with Depression/Depressive Tendencies
Diseases
depression
female participants
forest bathing
insulin-like growth factor I (IGF-1)
sleep
oxytocin
title Impacts of Forest Bathing (Shinrin-Yoku) in Female Participants with Depression/Depressive Tendencies
title_full Impacts of Forest Bathing (Shinrin-Yoku) in Female Participants with Depression/Depressive Tendencies
title_fullStr Impacts of Forest Bathing (Shinrin-Yoku) in Female Participants with Depression/Depressive Tendencies
title_full_unstemmed Impacts of Forest Bathing (Shinrin-Yoku) in Female Participants with Depression/Depressive Tendencies
title_short Impacts of Forest Bathing (Shinrin-Yoku) in Female Participants with Depression/Depressive Tendencies
title_sort impacts of forest bathing shinrin yoku in female participants with depression depressive tendencies
topic depression
female participants
forest bathing
insulin-like growth factor I (IGF-1)
sleep
oxytocin
url https://www.mdpi.com/2079-9721/13/4/100
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