An ethical framework for human genomic enhancement in China
Human genomic enhancement, or HGE, which improves human traits by introducing genetic and epigenetic changes, has garnered a lot of attention in light of the astounding advancement in genome editing techniques, such as CRISPR-Cas9, in recent years. This study combines doctrinal and empirical analysi...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-05-01
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| Series: | Frontiers in Genetics |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fgene.2025.1600829/full |
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| _version_ | 1849321616097411072 |
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| author | Fanhong Chen Hongjiao Zhang |
| author_facet | Fanhong Chen Hongjiao Zhang |
| author_sort | Fanhong Chen |
| collection | DOAJ |
| description | Human genomic enhancement, or HGE, which improves human traits by introducing genetic and epigenetic changes, has garnered a lot of attention in light of the astounding advancement in genome editing techniques, such as CRISPR-Cas9, in recent years. This study combines doctrinal and empirical analysis methods to examine bioethical issues of HGE in China. The literature currently in publication on these issues indicates that the majority of Chinese academics and the general public are enthusiastic about the present and potential future applications of genome editing techniques within the parameters of appropriate ethical guidelines; regrettably, no workable ethical governance framework has been put forth so far. Considering this, this study offers a more comprehensive discussion of ethical policy on HGE and develops a robust ethical framework that addresses three related issues about HGE: (1) approaching the precautionary principle as an overarching benchmark; (2) producing a multi-stakeholder collaborative governance model to promote stakeholder engagement and dialogue; and (3) establishing regional ethics review centers to have an independent review process. This is done in an effort to address ethical concerns and further inform policymaking on HGE in China. |
| format | Article |
| id | doaj-art-45eb5fb57ce9479ba82d242d05d1e4c2 |
| institution | Kabale University |
| issn | 1664-8021 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Genetics |
| spelling | doaj-art-45eb5fb57ce9479ba82d242d05d1e4c22025-08-20T03:49:42ZengFrontiers Media S.A.Frontiers in Genetics1664-80212025-05-011610.3389/fgene.2025.16008291600829An ethical framework for human genomic enhancement in ChinaFanhong ChenHongjiao ZhangHuman genomic enhancement, or HGE, which improves human traits by introducing genetic and epigenetic changes, has garnered a lot of attention in light of the astounding advancement in genome editing techniques, such as CRISPR-Cas9, in recent years. This study combines doctrinal and empirical analysis methods to examine bioethical issues of HGE in China. The literature currently in publication on these issues indicates that the majority of Chinese academics and the general public are enthusiastic about the present and potential future applications of genome editing techniques within the parameters of appropriate ethical guidelines; regrettably, no workable ethical governance framework has been put forth so far. Considering this, this study offers a more comprehensive discussion of ethical policy on HGE and develops a robust ethical framework that addresses three related issues about HGE: (1) approaching the precautionary principle as an overarching benchmark; (2) producing a multi-stakeholder collaborative governance model to promote stakeholder engagement and dialogue; and (3) establishing regional ethics review centers to have an independent review process. This is done in an effort to address ethical concerns and further inform policymaking on HGE in China. https://www.frontiersin.org/articles/10.3389/fgene.2025.1600829/fullhuman genomic enhancementCRISPR-Cas9ethicsgene editing technologyChina |
| spellingShingle | Fanhong Chen Hongjiao Zhang An ethical framework for human genomic enhancement in China Frontiers in Genetics human genomic enhancement CRISPR-Cas9 ethics gene editing technology China |
| title | An ethical framework for human genomic enhancement in China |
| title_full | An ethical framework for human genomic enhancement in China |
| title_fullStr | An ethical framework for human genomic enhancement in China |
| title_full_unstemmed | An ethical framework for human genomic enhancement in China |
| title_short | An ethical framework for human genomic enhancement in China |
| title_sort | ethical framework for human genomic enhancement in china |
| topic | human genomic enhancement CRISPR-Cas9 ethics gene editing technology China |
| url | https://www.frontiersin.org/articles/10.3389/fgene.2025.1600829/full |
| work_keys_str_mv | AT fanhongchen anethicalframeworkforhumangenomicenhancementinchina AT hongjiaozhang anethicalframeworkforhumangenomicenhancementinchina AT fanhongchen ethicalframeworkforhumangenomicenhancementinchina AT hongjiaozhang ethicalframeworkforhumangenomicenhancementinchina |