From Waste to Wealth: Efficient α-Amylase Production Using Agro-Waste Materials: A Study on Brevibacillus Isolates

Soil microbiota serves as a rich source of different microbial enzymes including α-amylase. In this study we aimed to isolate, optimize amylase-producing bacterial strains, and evaluate the effectiveness of agro-waste in replacing conventional starch-based fermentation substrates. Soil samples were...

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Main Authors: Fabiha Shahid, Syeda Soran Alam, Aima Arooj, Hafsa Batool
Format: Article
Language:English
Published: ResearchersLinks, Ltd 2025-06-01
Series:Novel Research in Microbiology Journal
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Online Access:https://researcherslinks.com/current-issues/From-Waste-to-Wealth-Efficient-Amylase-Production/44/1/11293/html
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author Fabiha Shahid
Syeda Soran Alam
Aima Arooj
Hafsa Batool
author_facet Fabiha Shahid
Syeda Soran Alam
Aima Arooj
Hafsa Batool
author_sort Fabiha Shahid
collection DOAJ
description Soil microbiota serves as a rich source of different microbial enzymes including α-amylase. In this study we aimed to isolate, optimize amylase-producing bacterial strains, and evaluate the effectiveness of agro-waste in replacing conventional starch-based fermentation substrates. Soil samples were collected from different areas of Pakistan. Bacteria that produce α-amylase were isolated and characterized. Initial screening in vitro was performed by starch hydrolysis assay. This process resulted in the identification of two promising bacterial isolates, AU1 and AU2, which were further characterized through biochemical testing and 16S rRNA sequencing. They were identified as Brevibacillus reuszeri and Brevibacillus brevis, respectively. Optimization of the fermentation conditions revealed optimal pH 7, temperature of 38 °C, incubation period of 72 h, and yeast extract as an organic nitrogen source. Additionally, using different agro-waste, general waste, and several sources of starch including corn comb, wheat bran, rice bran, potato peel, rice starch, potato starch, and corn starch, Brevibacillus reuszeri, and Brevibacillus brevis were tested for the production of α-amylase. The maximum amylase production was observed by Brevibacillus reuszeri with wheat bran (381 μmol/ min.) and Brevibacillus brevis with potato peel (395 μmol/ min.). Our research provides significant insights into the optimization of the fermentation processes for α-amylase production, highlighting the economic and sustainable potential of utilizing agro-waste materials in enzyme production industries.
format Article
id doaj-art-45e8dff90d0a468e8bb17c4eb0ea39ac
institution Kabale University
issn 2537-0286
2537-0294
language English
publishDate 2025-06-01
publisher ResearchersLinks, Ltd
record_format Article
series Novel Research in Microbiology Journal
spelling doaj-art-45e8dff90d0a468e8bb17c4eb0ea39ac2025-08-20T03:45:02ZengResearchersLinks, LtdNovel Research in Microbiology Journal2537-02862537-02942025-06-0193166177https://dx.doi.org/10.17582/journal.NRMJ/2025/9.3.166.177From Waste to Wealth: Efficient α-Amylase Production Using Agro-Waste Materials: A Study on Brevibacillus IsolatesFabiha Shahid0Syeda Soran Alam1Aima Arooj 2Hafsa Batool3Institute of Industrial Biotechnology Department, Government College University Lahore, 54000, Pakistan.Institute of Industrial Biotechnology Department, Government College University Lahore, 54000, Pakistan.Institute of Industrial Biotechnology Department, Government College University Lahore, 54000, Pakistan.Institute of Industrial Biotechnology Department, Government College University Lahore, 54000, Pakistan.Soil microbiota serves as a rich source of different microbial enzymes including α-amylase. In this study we aimed to isolate, optimize amylase-producing bacterial strains, and evaluate the effectiveness of agro-waste in replacing conventional starch-based fermentation substrates. Soil samples were collected from different areas of Pakistan. Bacteria that produce α-amylase were isolated and characterized. Initial screening in vitro was performed by starch hydrolysis assay. This process resulted in the identification of two promising bacterial isolates, AU1 and AU2, which were further characterized through biochemical testing and 16S rRNA sequencing. They were identified as Brevibacillus reuszeri and Brevibacillus brevis, respectively. Optimization of the fermentation conditions revealed optimal pH 7, temperature of 38 °C, incubation period of 72 h, and yeast extract as an organic nitrogen source. Additionally, using different agro-waste, general waste, and several sources of starch including corn comb, wheat bran, rice bran, potato peel, rice starch, potato starch, and corn starch, Brevibacillus reuszeri, and Brevibacillus brevis were tested for the production of α-amylase. The maximum amylase production was observed by Brevibacillus reuszeri with wheat bran (381 μmol/ min.) and Brevibacillus brevis with potato peel (395 μmol/ min.). Our research provides significant insights into the optimization of the fermentation processes for α-amylase production, highlighting the economic and sustainable potential of utilizing agro-waste materials in enzyme production industries.https://researcherslinks.com/current-issues/From-Waste-to-Wealth-Efficient-Amylase-Production/44/1/11293/htmlagro-wasteamylasestarch hydrolysis assayeconomic substratesoptimizationyeast extract
spellingShingle Fabiha Shahid
Syeda Soran Alam
Aima Arooj
Hafsa Batool
From Waste to Wealth: Efficient α-Amylase Production Using Agro-Waste Materials: A Study on Brevibacillus Isolates
Novel Research in Microbiology Journal
agro-waste
amylase
starch hydrolysis assay
economic substrates
optimization
yeast extract
title From Waste to Wealth: Efficient α-Amylase Production Using Agro-Waste Materials: A Study on Brevibacillus Isolates
title_full From Waste to Wealth: Efficient α-Amylase Production Using Agro-Waste Materials: A Study on Brevibacillus Isolates
title_fullStr From Waste to Wealth: Efficient α-Amylase Production Using Agro-Waste Materials: A Study on Brevibacillus Isolates
title_full_unstemmed From Waste to Wealth: Efficient α-Amylase Production Using Agro-Waste Materials: A Study on Brevibacillus Isolates
title_short From Waste to Wealth: Efficient α-Amylase Production Using Agro-Waste Materials: A Study on Brevibacillus Isolates
title_sort from waste to wealth efficient α amylase production using agro waste materials a study on brevibacillus isolates
topic agro-waste
amylase
starch hydrolysis assay
economic substrates
optimization
yeast extract
url https://researcherslinks.com/current-issues/From-Waste-to-Wealth-Efficient-Amylase-Production/44/1/11293/html
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