Multifaceted profiling of virus-specific CD8 T cells reveals distinct immune signatures against cytomegalovirus infection states during pregnancy

Multifaceted profiling of virus-specific CD8 T cells reveals distinct immune signatures against cytomegalovirus infection states during pregnancy

Summary: Anti-cytomegalovirus (CMV) serological testing, including the IgG avidity index (AI), is used to assess CMV infection phases during pregnancy. However, little is known about anti-CMV cellular immunity during pregnancy, particularly its relation to serological diagnosis. Herein, using MHC-de...

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Bibliographic Details
Main Authors: Ayumi Taguchi, Fumi Misumi, Shunsuke Teraguchi, Takeshi Nagamatsu, Shuhei Sakakibara, Tomohiro Otani, Mari Ichinose, David Priest, Kazuki Nakajima, Junko Nakamura, Ryoko Sawada, Tatsuo Suzutani, Toshiyuki Ikeda, Yutaka Nagura, Takayuki Iriyama, Daisuke Okuzaki, Hitoshi Okazaki, James B. Wing, Yasushi Hirota, Yutaka Osuga
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:iScience
Subjects:
biological sciences
immunology
pregnancy
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225006777
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